Fruquintinib, a standard third-line treatment option for metastatic colorectal cancer (mCRC), has been shown to significantly prolong both overall survival (OS) and progression-free (PFS) in patients. However, we have observed that the dosing of fruquintinib is frequently associated with higher incidence adverse effects within Chinese population, leading some patients-particularly elderly individuals-to be unable tolerate it. This study presents retrospective analysis evaluate therapeutic...

With the construction of a large number hydropower stations, transmission lines crossing river and urban utility tunnels, gas insulated line (GIL) has been applied widely due to its capacity, low environmental impact high reliability. Accurate modelling physical quantities their characteristics GIL provides theoretical basis for design operation, which is great significance ensure safety reliability operation. The mathematical model relationship multi-physical fields are analyzed at first,...

Detecting insulation flaws in HVDC apparatus, where partial discharge (PD) may occur can help preventing failures, even if the degradation rate under PD is much slower than AC conditions. In order to improve reliability of systems and, particular transmission lines, it would be important distinguish defects different harmfulness. However, DC voltage concept phase-resolved pattern loses meaning and conventional techniques for source identification are no longer applicable. Techniques based on...

The concentration of trace and rare earth elements in 22 crude oil five oilfield water samples, collected from Triassic Yanchang Formation Jurassic Yanan reservoirs the Jiyuan Area Ordos Basin, N China, was determined using inductively coupled plasma mass spectrometry (ICP‐MS) for first time. samples were analysed to classify oils into family determine origin depositional environment organic matter that yield elements. REE chondrite‐normalized distribution patterns show light element (LREE)...

Partial discharges (PD) in HVDC equipment are not the predominant degradation factor. However, they can be a failure precursor (particularly when electrical trees formed), so that monitoring PD could tool to infer imminent failures. In order monitor on site, one major problem at DC voltage is absence of tools able distinguish noise from signals. this paper, corona, surface and internal measured under extracted interference resorting new strategy rejection voltage.

Suppressing narrow-band interference is one of the key techniques partial discharge (PD) on-line monitoring. Based on characteristics analysis FFT power spectrum PD signals with and without interference, peaks energy ratio defined. Thus, a method suppressing using pretreatment proposed, steps are also detailed. Besides, magnitude fuzzified adaptive fuzzy C-mean threshold algorithm proposed to extract ratio. The denoising results show that could pick from real signal.

This paper discusses noise rejection and PD source identification in HVDC systems. The approach resorts to separation of sources first. Separation aiming at grouping the data according their pulse shape is carried out exploiting features recorded pulses. Identification achieved through statistical analysis inter-times magnitudes. In particular, measurement statistics are compared using a fuzzy inference system with those reference database, obtained lab testing.

The cable ampacity is closely related with its laying way and heat dissipation performance of the surrounding medium. With multi ways, in ducts thermal bottleneck that constrains whole line's ampacity. conductor temperature could be reduced current-carrying capacity duct enhanced by filling medium low resistivity duct. By calculation software which tested experiment ampacity, different arrangement condition calculated this paper, relationships between analyzed. Meanwhile, experiments are...

The rotor position detection without sensor is very important for permanent magnet brushless DC motor (PM-BLDCM) to fulfil its electric commutation and speed control, a novel method, based on the spatial saliency tracking scheme was presented. method employed high-frequency voltage-signal injection make form current vector, of which negative component contained information. By observer, with heterodyning processing adopted, signal can be picked up then implemented any specialized mechanical...

Aiming at the shortcomings of traditional hard threshold method and soft method, this paper puts forward a wavelet de-noising based on entropy improved function. First, noisy partial discharge (PD) signals are processed by decomposition, then coefficients new function using adaptive selection entropy, finally denoised signal can be got reconstruction. The results typical simulative field reveal that present remove white noise effectively.

Partial discharge is an important cause of the deterioration cable insulation condition, and also manifestation deteriorated condition. detection for means to find defects assess state insulation. signals from different sources have great harm power equipment, so pattern identification purpose in this research. First, four kinds waveforms are processed by de-noising preprocessing, then decomposed wavelet packet, finally energy percentage frequency bands can be obtained. Studies show that...

It is difficult to directly measure the transient conductor temperature of operating cable, however, which plays a significant role in reflecting its operation state and controlling load. So it essential calculate monitor cable temperature. A model calculating based on support vector machine (SVM) proposed this dissertation. In model, particle swarm optimization (PSO) algorithm introduced improve calculation accuracy avoid blindly selecting training parameters, taking skin load current as...

Discharge Characteristic of external insulation is significantly influenced by Humidity. Most researches concern on low humidity condition. tests air gap are carried out in the artificial climatic chamber whose could be adjusted conveniently. The relation between (especially for high humidity) and discharge voltage studied this paper. It shown that increases with increase when relative less than 80%. Dewdrop electrode surface plays an important role. Above 80%RH, decreases slightly without...

If lightning strikes on an overhead line connected with a cable, over voltage will invade into this cable and induct in its metal sheath. The sheath-lightning-overvoltage (SLOV) under one-terminal-grounding connection (OTGC) cross-bonding (CBC) are simulated; impulsive test was undertaken real of Guangzhou power system. However it is hard to get the exact models parameters. In paper, based SLOV simulation, effects several factors, such as structure length, stricken wave shape, magnitude...

The infrared thermal image is an importance in condition monitoring of electrical equipment. However, the edge coarse, fuzzy, and with serious noise brings great inconvenience to processing. An adaptive optimal threshold extraction algorithm based on improved Sobel operator proposed this paper. In algorithm, by eight-direction operators extracted high temperature area noisy environment. At same time, wavelet coefficients sub-band are described general Gaussian distribution variance estimated...

The sheath and the shed in China are made of high temperature vulcanized (HTV) silicone rubber. ferric oxide powder is widely used as red colorant, it cannot disperse uniformly rubber for reason that inorganic. In paper, adding way amount changed specimen-making process. Through hot air aging test, changes specimen's electrical performances, mechanical properties microstructure considered, so influence colorant on property under environment has been discussed. results show color masterbatch...

The load varies periodically, but the peak current of power cable is controlled by its continuous ampacity in China, resulting highest conductor temperature much lower than 90℃, permitted long-term working XLPE.If cyclic ampacity, transmission capacity could be used sufficiently.To study 10 kV XLPE and factor, a three-core calculation software developed experiments direct buried are undertaken this paper.Experiments research shows that correct circuit numbers daily factor have an important...