A5025908720- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Maternal and fetal healthcare
- Cardiac electrophysiology and arrhythmias
- Blood donation and transfusion practices
- Cardiovascular Effects of Exercise
- Blood groups and transfusion
- Appendicitis Diagnosis and Management
- Neonatal Health and Biochemistry
- Cardiac, Anesthesia and Surgical Outcomes
- Trauma and Emergency Care Studies
- Radiology practices and education
- Cardiac Arrhythmias and Treatments
- Pregnancy and preeclampsia studies
- Apelin-related biomedical research
- Diet and metabolism studies
- Endometriosis Research and Treatment
- Trigeminal Neuralgia and Treatments
- Medical and Health Sciences Research
- South African History and Culture
- Hepatitis Viruses Studies and Epidemiology
- Vitamin D Research Studies
- Methemoglobinemia and Tumor Lysis Syndrome
- Global Maternal and Child Health
- Psychotherapy Techniques and Applications
Stellenbosch University
1975-2025
Université de Nîmes
2025
Lung Institute
2022
University of Cape Town
2022
South African Tuberculosis Vaccine Initiative
2022
SUNY Downstate Health Sciences University
2003
Tygerberg Hospital
1975
University of Groningen
1957-1962
Amyotrophic lateral sclerosis (ALS) is a life-threatening disease characterised by progressive loss of motor neurons with few therapeutic options. The MIROCALS study tested the hypothesis that low-dose interleukin-2 (IL-2LD) improves survival and function in ALS. In this randomised, double-blind, placebo-controlled trial, male female riluzole-naive participants, either possible, laboratory-supported probable, or definite ALS diagnosis (revised El Escorial criteria), aged 18-76 years, symptom...
Bloodstream infections (BSIs) significantly contribute to the morbidity and mortality in paediatric burn patients from low- middle-income countries; with common pathogens like Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa frequently being multidrug resistant (MDR). Due growing prevalence of MDR BSIs, antimicrobial stewardship needs be improved perhaps more targeted initial use. The study describes aetiology, timing burn-associated BSIs admitted two surgery units Tshwane...
The effect of propofol and thiopentone on cerebral (CBF), myocardial (MBF), muscular, arterial hepatic blood flow was assessed with radiolabelled microspheres in 12 chronically instrumented dogs, six given thiopentone. Tissue flows were measured the awake animal, after 30 min normoxic anaesthesia (room air), hypoxic using a mixture 10% O2 3% CO2 nitrogen. decrease CBF from to similar (propofol: 77 +/- 8 38 3 ml min-1 100 g-1, P < 0.01; thiopentone: 66 33 2 0.01). During hypoxia, rose...
Early HIV testing is needed for treatment success in young infants, but universal expensive. In this study, we examined the feasibility of early infant risk scores targeted polymerase chain reaction (PCR) and diagnosis.A cross-sectional cohort newborns exposed to was enrolled PCR tested within 72 hours. We quantified associations between infection clinical laboratory maternal-infant parameters by logistic regression models determined sensitivity specificity derived scores.From August 2014...
Background. An ectopic pregnancy can be a life-threatening condition. Early diagnosis with ultrasonography and quantitative beta-human chorionic gonadotrophin (β-hCG) measurement has improved early accurate treatment. Medical management methotrexate internationally success rate of up to 93%, but there is paucity data on this treatment option in developing countries. Objective. To determine the for pregnancies at referral hospital country. This non-surgical, outpatient seems good hospitals an...
A retrospective observational study of new patients who visited the gynaecology outpatient clinic at Tygerberg Hospital, South Africa, between February and June 2019 was conducted to determine association body mass index (BMI) gynaecological disorders. BMI calculated analysed concerning presenting complaint final diagnosis. From sample 651 patients, 18.4% had a normal 47.3% were classified as overweight or obese class 1. Older age associated with higher (p = .013). Hypertension most...
The Montreal Cognitive Assessment (MoCA) test is a widely used tool to screen for mild neurocognitive impairment. However, its structural validity has not been fully described in South Africa. study aimed replicate and extend earlier work with African samples, provide an expanded description of the psychometric properties MoCA. examined MoCA sample neurocognitively healthy working adults (N = 402) individuals diagnosed disorders 42); both groups reported good English proficiency. Analysis...
Objective To assess the perceived usefulness and ease of use a Brass V-drape versus Maternawell tray for collection postpartum blood loss. Design Prospective parallel randomised controlled trial Setting Site B Midwife Obstetric Unit, Khayelitsha, Cape Town, South Africa Sample Sixty-three participants were recruited, 30 in drape arm 33 arm. Methods This was prospective trail. Low risk term pregnant women presenting early labour approached voluntary participation. Informed consent obtained,...
Background . Postpartum haemorrhage is the leading cause of preventable maternal mortality worldwide. Early identification and prompt management postpartum improve outcomes. Objective assessment blood loss an important step in identifying haemorrhage. The Brass‐V drape MaternaWell tray have been designed for routine measurement loss. perceived utility acceptability these devices to parturients birth attendants still begged exploring. To assess usefulness ease use a versus collection Methods...
Morbid obesity and prolonged pregnancy are independently associated with adverse delivery perinatal outcomes. We conducted a retrospective observational study on otherwise uncomplicated women body mass index (BMI) ≥ 40 kg/m2 where, having reached term, induction of labour (IOL) was planned, to prevent pregnancy. The primary aim describe outcomes short-term maternal events. Of 117 cases included, 69 (59%) laboured spontaneously before the date, while 48 (41%) required an IOL. patients that...