A5026554358- Trypanosoma species research and implications
- Signaling Pathways in Disease
- Gyrotron and Vacuum Electronics Research
- Galectins and Cancer Biology
- Acoustic Wave Resonator Technologies
- HIV Research and Treatment
- Biochemical and Molecular Research
- Plant Virus Research Studies
- Microwave Engineering and Waveguides
- Research on Leishmaniasis Studies
Stellenbosch University
2013-2022
University of the Free State
2014
Trypanosomes diverged from the main eukaryotic lineage about 600 million years ago, and display some unusual genomic epigenetic properties that provide valuable insight into early processes employed by ancestors to regulate chromatin-mediated functions. We analysed Trypanosoma brucei core histones high mass accuracy middle-down spectrometry map histone post-translational modifications (PTMs) elucidate cis-histone combinatorial PTMs (cPTMs). T. are heavily modified intricate cPTMs patterns,...
The compaction of DNA in chromatin eukaryotes allowed the expansion genome size and coincided with significant evolutionary diversification. However, generally represses function, mechanisms coevolved to regulate structure its impact on DNA. This included selection specific nucleosome positions modulate accessibility molecule. Trypanosoma brucei, a member Excavates supergroup, falls an ancient branch provides valuable insight into organization early genomes. We have mapped T. brucei...
A low phase noise oscillator operating at 9.2 GHz is presented. cylindrical metal cavity with air as dielectric used the resonator. To minimize of oscillator, resonator must be designed to have a high quality factor (Q-factor). Q-factor obtained by designing operate in TE <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">011</sub> mode. tuning screw tune resonant frequency without significantly affecting Q-factor, while also separating frequencies...