A5022654088- Pregnancy and preeclampsia studies
- Renal Diseases and Glomerulopathies
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Reproductive System and Pregnancy
- Dental Health and Care Utilization
- Dental Erosion and Treatment
- Oral microbiology and periodontitis research
Sri Ramachandra Institute of Higher Education and Research
2021-2024
Nephrotic syndrome is a common cause of kidney diseases in children. Many studies have examined the association microRNAs playing potential roles many pathophysiological functions. We investigated expression pattern miR-17-5P, miR-155p, miR-424-5p children with steroid sensitive nephrotic (SSNS) and resistance (SRNS), along healthy subjects. Total RNA was isolated from urine samples three groups (SSNS n = 100, SRNS control group 100). Bioinformatics tools such as miRWalk miR-Tar link were...
Abstract Background Nephrotic syndrome is one of the common cause among kidney disease in children worldwide .It characterised by edema proteinuria, hypoalbuminemia and hypocholestromia. Recently many studies have emerged with association microRNAs playing an potential roles pathophysiological functions. MicroRNAs(miRNAs ) RNA binding proteins (RBPs) are found to be two most important needed transcriptional regulators gene expression as well for aberrant that tend contribute development...
Abstract Background Recently, urinary exosomal miRNAs are gaining increasing attention as their expression profiles often associated with specific diseases and they exhibit great potential noninvasive biomarkers for the diagnosis of various diseases. The present study was aimed to evaluate status selected (miR-1, miR-215-5p, miR-335-5p let-7a-5p) in urine samples from children NS [steroid sensitive (SSNS)] resistant (SRNS)] along healthy control group. Methods MicroRNA isolation carried out...