A5036463500- Systemic Lupus Erythematosus Research
- Liver Diseases and Immunity
- Parasitic Infections and Diagnostics
- Biochemical Analysis and Sensing Techniques
- Metabolism, Diabetes, and Cancer
- Pregnancy and preeclampsia studies
- Autophagy in Disease and Therapy
- Circular RNAs in diseases
- Dialysis and Renal Disease Management
- Diabetes Treatment and Management
- Renal Diseases and Glomerulopathies
- Pediatric health and respiratory diseases
- Biochemical effects in animals
- melanin and skin pigmentation
- Neurological Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Breastfeeding Practices and Influences
- Chronic Kidney Disease and Diabetes
- MicroRNA in disease regulation
- Skin Protection and Aging
- Autoimmune Bullous Skin Diseases
Ain Shams University
2016-2024
Management of diabetic nephropathy (DN) is far from satisfactory. There a rising role the involvement phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway in pathogenesis DN. This study aimed at investigating renoprotective effects PI3K/AKT via sitagliptin rat model Thirty-two male Wistar rats were divided into four groups (eight each): (I) control, (II) sitagliptin, (III) DN, and (IV) DN + sitagliptin. Fasting blood glucose (FBG), kidney index, function tests both urine...
Abstract Background The predicted increase in the senior population will have a substantial impact on mental health and dementia development, emphasizing need to study biochemical components related pathogenesis of dementia. Oxidative stress is caused by an imbalance between production reactive oxygen species antioxidant balance body. brain particularly vulnerable oxidative because relatively low levels antioxidants brain, high polyunsaturated fatty acids, increased needs. leads accumulation...
Abstract Background and objectives Lupus nephritis (LN) is a severe clinical manifestation seen in individuals with systemic lupus erythematous (SLE). It has poor long-term prognosis pediatric patients high morbidity mortality rates. MicroRNAs (miRNAs) are noncoding small RNAs that act as epigenetic modulators, regulating gene expression, modulating the understanding of mechanisms pathogenesis human diseases. Depending on bioinformatics analysis, we aimed to investigate urinary expression...
Abstract Background and Aim Lupus Nephritis (LN) is a serious manifestation of systemic lupus erythematous (SLE) with poor prognosis for pediatric patients resulting in high morbidity mortality rates. MicroRNAs (miRNAs) are short, non-coding RNAs that serve as epigenetic modulators, affecting gene expression influencing our understanding disease causes pathology. Thus, we sought to explore urinary miR-663a LN among SLE children. Patients Methods The levels were estimated cellular pellets...
Background: Vitiligo is melanocyte death that affected by oxidative stress which elevated levels of reactive oxygen species can elicit an immune response, and ultimately cause melanocytic death.Objective: The current study aimed to investigate the impact Narrowband Ultraviolet B (NBUVB) excimer laser phototherapy on C-X-C motif chemokine receptor 3B expression in vitiligo patients its improvement.Patients methods: CXCR3B mRNA was measured skin 25 suffering from non-segmental before after...