Xiaoyan Guo

ORCID: 0000-0002-1445-4295
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About
Contact & Profiles
Research Areas
  • Pregnancy and Medication Impact
  • Reproductive System and Pregnancy
  • Prenatal Screening and Diagnostics
  • Endometriosis Research and Treatment
  • Reproductive Biology and Fertility
  • Assisted Reproductive Technology and Twin Pregnancy
  • Ectopic Pregnancy Diagnosis and Management
  • Chronic Lymphocytic Leukemia Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Adrenal Hormones and Disorders
  • Renal and related cancers
  • Uterine Myomas and Treatments
  • Sperm and Testicular Function
  • Gynecological conditions and treatments
  • Gestational Trophoblastic Disease Studies
  • Sexual Differentiation and Disorders
  • HER2/EGFR in Cancer Research
  • Ovarian function and disorders
  • Metabolism and Genetic Disorders
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

First Affiliated Hospital Zhejiang University
2024-2025

Hangzhou Medical College
2022-2024

Zhejiang Provincial People's Hospital
2022-2024

Reduced endometrium thickness and receptivity are two important reasons for recurrent implantation failure (RIF). In order to elucidate differences between these types of endometrial defects in terms molecular signatures, cellular interactions, structural changes, we systematically investigated the single-cell transcriptomic atlas across three distinct groups: RIF patients with thin (≤ 6 mm, TE-RIF), normal (≥ 8 NE-RIF), fertile individuals (Control).

10.1186/s12958-024-01263-1 article EN cc-by-nc-nd Reproductive Biology and Endocrinology 2024-07-31

How LH levels influenced the outcomes of monofollicular IVF cycles using different stimulation protocols was controversial. In this single-center, retrospective study, we analyzed 815 between 2016−2022 natural cycle (NC), medroxyprogesterone acetate (MPA) or clomiphene citrate (CC) in addition to human menopausal gonadotropin (hMG), with without GnRH antagonist. A viable embryo obtained 35.7% all cycles. Growth stagnation and premature surge are two markedly negative factors for obtaining...

10.3390/jcm11237140 article EN Journal of Clinical Medicine 2022-12-01

Multiple morphological abnormalities of sperm flagella (MMAF) indicate severe teratozoospermia. The fibrous sheath interacting protein 2 (FSIP2) plays an important role in the normal construction flagella. In this study, a novel compound heterozygous mutation site FSIP2, involving c.272_275delinsAGGTTTTTATA (p.L92Vfster74) and c.16788_16791del (p.E5596fs), was identified using whole-exome sequencing 32-year-old male. Electron microscope images revealed thick neck, scattered mitochondria,...

10.1155/2023/9222954 article EN Andrologia 2023-02-07

To analyze the pregnant outcomes in patients with positive anti-centromere antibody (ACA) receiving

10.3724/zdxbyxb-2023-0559 article EN PubMed 2024-05-27
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