A5061933473- Metal complexes synthesis and properties
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Ferrocene Chemistry and Applications
- Chemical Synthesis and Analysis
- DNA and Nucleic Acid Chemistry
- Synthesis of heterocyclic compounds
- Protein Interaction Studies and Fluorescence Analysis
- Organometallic Complex Synthesis and Catalysis
- Magnetism in coordination complexes
- Click Chemistry and Applications
- Lanthanide and Transition Metal Complexes
- Chemical synthesis and pharmacological studies
- Mass Spectrometry Techniques and Applications
- Molecular Sensors and Ion Detection
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Organic Chemistry Synthesis Methods
- Catalytic Cross-Coupling Reactions
- Crystallography and molecular interactions
- Corrosion Behavior and Inhibition
- Synthetic Organic Chemistry Methods
- Trace Elements in Health
- Synthesis and Reactivity of Heterocycles
- Polysaccharides and Plant Cell Walls
University of Kragujevac
2015-2024
A series of 16 Pt(<sc>ii</sc>) complexes with 8-hydroxyquinolines and sulfoxide/phosphine ligands were synthetized, characterized evaluated for cytotoxic embryotoxic activity.
Polynuclear Pt(II) complexes are a novel class of promising anticancer agents with potential clinical significance. A series pyrazine (pz) bridged dinuclear general formulas {[Pt(L)Cl]2(μ-pz)}2+ (L, ethylenediamine, en; (±)-1,2-propylenediamine, 1,2-pn; isobutylenediamine, ibn; trans-(±)-1,2-diaminocyclohexane, dach; 1,3-propylenediamine, 1,3-pd; 2,2-dimethyl-1,3-propylenediamine, 2,2-diMe-1,3-pd) and one pyridazine (pydz) {[Pt(en)Cl]2(μ-pydz)}2+ complex were prepared. The these determined...
The synthesis, spectroscopic characterization, cytotoxic activity and DNA binding evaluation of seven new dinuclear platinum(ii) complexes Pt1-Pt7, with the general formula [{Pt(L)Cl}2(μ-1,5-nphe)](ClO4)2 (1,5-nphe is 1,5-naphthyridine; while L two ammines (Pt1) or one bidentate coordinated diamine: ethylenediamine (Pt2), (±)-1,2-propylenediamine (Pt3), trans-(±)-1,2-diaminocyclohexane (Pt4), 1,3-propylenediamine (Pt5), 2,2-dimethyl-1,3-propylenediamine (Pt6), 1,3-pentanediamine (Pt7)), were...
The dinuclear platinum(II) complexes, [{PtCl(NH 3 ) 2 } ( μ ‐1,6‐nphe)](ClO 4 Pt1 and [{Pt(en)Cl} Pt2 (en is a bidentate‐coordinated ethylenediamine 1,6‐nphe the bridging 1,6‐naphthyridine ligand) were synthesized characterized by different spectroscopic methods. DNA‐binding evaluation of complexes was done UV–Vis, fluorescence emission spectroscopy, their interaction with bovine serum albumin (BSA). cytotoxic activity these determined against mouse breast (4T1) colon (CT26) cancer cell...
Monocationic gold(III) complexes with histidine-containing peptides, glycyl-L-histidine (Gly-L-His) and L-alanyl-L-histidine (L-Ala-L-His) have been synthesized characterized by 1H NMR spectroscopy X-ray crystallography. The crystallized Au(III) complexes, [Au(Gly-L-His-N,N′,N′′)Cl]NO3·1.25H2O [Au(L-Ala-L-His-N,N′,N′′)Cl]NO3·2.5H2O, were obtained from water solution at pH < 1.0. chemical shifts in the spectra of [Au(L-Ala-L-His-N,N′,N′′)Cl]NO3·2.5H2O compared those for corresponding Pd(II)...
Binuclear [{Pd (dien)} 2 ( μ ‐pz)](ClO 4 ) Pd1 and ‐pydz)](ClO Pd2 complexes, where pz is 1,4‐diazine pydz 1,2‐diazine bridging ligands dien (diethylenetriamine) a tridentately coordinated triamine ligand, were synthesized characterized using elemental analysis, NMR 1 H 13 C) spectroscopy, UV–Vis spectrophotometry. Electronic absorption spectrophotometry fluorescence spectroscopy used to study the interactions of prepared complexes with deoxyribonucleic acid (CT‐DNA) bovine serum albumin...
Dinuclear platinum(II) complexes, [{Pt(en)Cl} 2 (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>μ</mml:mi></mml:math>-qx)]Cl ·2H O ( 1 ), id="M2"><mml:mi>μ</mml:mi></mml:math>-qz)](ClO 4 ) and id="M3"><mml:mi>μ</mml:mi></mml:math>-phtz)]Cl ·4H 3 were synthesized characterized by different spectroscopic techniques. The crystal structure of was determined single-crystal X-ray diffraction analysis, while the DFT M06-2X method applied in order to optimize structures 1–3...
A novel phosphine-free ferrocene-containing Pd complex is an excellent precatalyst for Suzuki–Miyaura coupling.