A5010123347- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Algorithms and Data Compression
- Network Packet Processing and Optimization
- Environmental DNA in Biodiversity Studies
- Invertebrate Immune Response Mechanisms
- Insect-Plant Interactions and Control
- Forensic Anthropology and Bioarchaeology Studies
- Insect symbiosis and bacterial influences
- Archaeology and ancient environmental studies
- Yersinia bacterium, plague, ectoparasites research
- Web Data Mining and Analysis
- Historical and Archaeological Studies
University of Leicester
2018-2022
National Institute of Standards and Technology
2021-2022
Material Measurement Laboratory
2022
Centre National de la Recherche Scientifique
2008
University of Szeged
2008
Institut de Biologie Moléculaire et Cellulaire
2008
Short tandem repeats on the male-specific region of Y chromosome (Y-STRs) are permanently linked as haplotypes, and therefore Y-STR sequence diversity can be considered within robust framework a phylogeny haplogroups defined by single nucleotide polymorphisms (SNPs). Here we use massively parallel sequencing (MPS) to analyse 23 Y-STRs in Promega's prototype PowerSeq™ Auto/Mito/Y System kit (containing markers PowerPlex® Y23 [PPY23] System) set 100 diverse chromosomes whose phylogenetic...
This manuscript reports Y-chromosomal short tandem repeat (Y-STR) haplotypes for 1032 male U.S. population samples across 30 Y-STR loci characterized by three capillary electrophoresis (CE) length-based kits (PowerPlex Y23 System, Yfiler Plus PCR Amplification Kit, and Investigator Argus Y-28 QS Kit) one sequence-based kit (ForenSeq DNA Signature Prep Kit): DYF387S1, DYS19, DYS385 a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS449, DYS456, DYS458,...
Abstract The influence of Viking-Age migrants to the British Isles is obvious in archaeological and place-names evidence, but their demographic impact has been unclear. Autosomal genetic analyses support Norse Viking contributions parts Britain, show no signal corresponding Danelaw, region under Scandinavian administrative control from ninth eleventh centuries. Y-chromosome haplogroup R1a1 considered as a possible marker for migrations because its high frequency peninsular Scandinavia...
Sequence analysis of the mitochondrial DNA (mtDNA) control region can provide forensically useful information, particularly in challenging samples where autosomal profiling fails. Sub-division 1122-bp into shorter PCR fragments improves data recovery, and such be analysed together via massively parallel sequencing (MPS). Here, we generate mtDNA using prototype PowerSeq™ Auto/Mito/Y System (Promega) MPS assay, which a single reaction amplifies ten overlapping amplicons region, set 101 highly...
Short tandem repeat (STR) polymorphisms are traditionally assessed by measuring allele lengths via capillary electrophoresis (CE). Massively parallel sequencing (MPS) reveals differences among alleles of the same length, thus improving discrimination, but also identifying groups likely related descent. These may have relatively restricted geographical distributions and MPS could detect population structure more effectively than CE-based analysis. We addressed this question applying an...
String edit distances have been used for decades in applications ranging from spelling correction and web search suggestions to DNA analysis. Most string are variations of the Levenshtein distance consider only single-character edits. In forensic polymorphic genetic markers such as short tandem repeats (STRs) used. At these repetitive motifs copying errors consist more than just single base differences. More often phenomenon “stutter” is observed, where number repeated units differs (by...