Marı́a Elena Hernández

ORCID: 0000-0002-1617-5636
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About
Contact & Profiles
Research Areas
  • Hormonal and reproductive studies
  • Autism Spectrum Disorder Research
  • Urinary Bladder and Prostate Research
  • Hypothalamic control of reproductive hormones
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Prostate Cancer Treatment and Research
  • Vestibular and auditory disorders
  • Sexual function and dysfunction studies
  • Stress Responses and Cortisol
  • Neuroendocrine regulation and behavior
  • Neuroscience and Neuropharmacology Research
  • Cholinesterase and Neurodegenerative Diseases
  • Diet and metabolism studies
  • Parkinson's Disease Mechanisms and Treatments
  • Sperm and Testicular Function
  • Adipose Tissue and Metabolism
  • Tryptophan and brain disorders
  • Sexual Differentiation and Disorders
  • Estrogen and related hormone effects
  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Protease and Inhibitor Mechanisms
  • Health and Lifestyle Studies
  • Diabetes and associated disorders

Universidad Veracruzana
2016-2025

Madrid Health Service
2024

Benito Juárez Autonomous University of Oaxaca
2023

Universidad de Tijuana
2022

Centro de Investigaciones Cardiovasculares
2019-2021

Autonomous University of Tlaxcala
1997-2020

Western University
2020

Universidad de Xalapa
2016

Center for Special Minimally Invasive and Robotic Surgery
2015

University of Minnesota
2015

We conducted an observational study of 15 patients from a Southeastern area Mexico with symptoms compatible SARS-Cov-2, which were treated the antiviral amantadine. In this study, data collected individuals clinical COVID-19 infection, on ambulatory basis 100 mg amantadine for period 14 days. This drug demonstrated its effectiveness, as recovered successfully treatment without necessity attending hospital to use mechanical ventilation. All developed IgG antibodies SARS-Cov-2. Amantadine can...

10.1007/s43440-020-00168-1 article EN other-oa Pharmacological Reports 2020-10-10

The prostate gland, a male accessory reproductive organ, is regulated by hormonal inputs and autonomic innervation from the major pelvic ganglion. This study examined effects of ganglion denervation on histology, immune cell infiltration, systemic levels prolactin, testosterone, cytokines in rats. Male Wistar rats (300–350 g) were divided into groups receiving bilateral axotomy hypogastric nerve, or both, alongside sham-operated control. After 15 days, animals sacrified, tissue was...

10.20944/preprints202504.1539.v1 preprint EN 2025-04-18

The etiology of autism spectrum disorder (ASD) has been linked to both genetic and epigenetic factors. Among the factors, exposure valproic acid (VPA), an antiepileptic mood-modulating drug, shown induce characteristic traits ASD when exposed during embryogenesis. Conversely, in animal models, enriched environment (EE) demonstrated positive behavioral neural effects, suggesting its potential as a complementary treatment pharmacological approaches central nervous system disorders. In this...

10.3390/neurosci5020009 article EN cc-by NeuroSci 2024-04-22

Background: Alzheimer’s disease (AD), the leading cause of dementia worldwide, poses an increasing global health burden, yet its pathogenesis remains poorly understood. Diabetes mellitus (DM), characterized by chronic hyperglycemia, has been identified as a significant risk factor for AD development, suggesting potential metabolic and molecular link between these diseases. Methods: This study examines impact sustained high glucose levels on astrocyte-like C6 glial cells, focusing key...

10.3390/biomed5010003 article EN cc-by BioMed 2025-01-09

El piso pélvico (PP) es una estructura anatómica compleja que participa en diversas funciones, tales como el soporte de los órganos pélvicos, control la continencia y función sexual. Las alteraciones esta región tienen un impacto significativo calidad vida individuos. Sin embargo, las investigaciones sobre su disfunción han sido menos exploradas sexo masculino comparación con femenino. En ámbito neurociencias fisiología, modelos animales proporcionado herramientas esenciales para estudiar...

10.25009/eb.v16i40.2641 article ES cc-by-nc eNeurobiología 2025-01-27

El ganglio pélvico mayor (GPM) forma parte del sistema nervioso periférico, inerva a diversos órganos área pélvica incluyendo la próstata y se ha mostrado que contiene receptores hormonas esteroides prolactina (PRL). En trabajos anteriores mostró ni ejecución de conducta sexual denervación preganglionar cambian expresión receptor PRL (RPRL) en GPM, aunque condiciones hiperprolactinemia altera su morfología e histología. La ejerce sus funciones mediante cual han reportado al menos tres...

10.25009/eb.v16i41.2642 article ES cc-by-nc eNeurobiología 2025-01-15

Los testículos son órganos esenciales del sistema reproductor masculino, cuya principal función es llevar a cabo la espermatogénesis y sintetizar hormonas sexuales, especialmente testosterona. Se sabe que estos están regulados por el eje hipotálamo-hipófisis-testículo (HHT), en cual participan como luteinizante (LH), foliculoestimulante (FSH) testosterona (T), así mismo se ha documentado nervioso autónomo (SNA) desempeña un papel su regulación través de nervios autonómicos. Uno componentes...

10.25009/eb.v16i41.2645 article ES cc-by-nc eNeurobiología 2025-05-05

The prostate is a key gland in the sexual physiology of male mammals. Its sensitivity to steroid hormones widely known, but its response prolactin still poorly known. Previous studies have shown correlation between behaviour, release and physiology. Thus, here we used behaviour rats as model for studying this correlation. Hence, developed experimental paradigms determine influence on organization rats. In addition recordings, ELISA procedure quantify serum level prolactin, hematoxilin-eosin...

10.1186/1477-7827-4-28 article EN cc-by Reproductive Biology and Endocrinology 2006-05-17

Abstract Valproic acid (VPA) is an anti‐epileptic drug with teratogenicity activity that has been related to autism. In rodents, exposure VPA in utero leads brain abnormalities similar than those reported the autistic brain. Particularly, reduces number of Purkinje neurons rat cerebellum parallel cerebellar found Thus, we injected pregnant females on embryonic day 12 either (600 mg/kg, i.p.) or 0.9% saline solution and obtained from their offspring at different postnatal time points....

10.1016/j.ijdevneu.2016.07.001 article EN International Journal of Developmental Neuroscience 2016-07-14

The prostate is a sexual gland that produces important substances for the potency of sperm to fertilize eggs within female reproductive tract, and under complex endocrine control. Taking advantage peculiar behavioral pattern copulating male rats, we developed experimental paradigms determine influence behavior on level serum testosterone, androgen receptors, mRNA receptors in rats displaying up four consecutive ejaculations. effect ejaculations was investigated by determining levels (i)...

10.1186/1477-7827-5-11 article EN cc-by Reproductive Biology and Endocrinology 2007-03-16
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