A5025147406- Opioid Use Disorder Treatment
- Pharmaceutical Practices and Patient Outcomes
- Hepatitis C virus research
- Respiratory and Cough-Related Research
- HIV, Drug Use, Sexual Risk
- Pain Management and Opioid Use
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent and Pediatric Healthcare
- Asthma and respiratory diseases
- Musculoskeletal pain and rehabilitation
- Liver Disease Diagnosis and Treatment
- Prenatal Substance Exposure Effects
- Autoimmune and Inflammatory Disorders Research
- Pneumonia and Respiratory Infections
- Migraine and Headache Studies
- Medication Adherence and Compliance
- Pharmacy and Medical Practices
- Patient Safety and Medication Errors
- Cardiac Arrest and Resuscitation
- Substance Abuse Treatment and Outcomes
- Global Health Care Issues
- Sleep and Wakefulness Research
- Innovations in Medical Education
- Cardiac, Anesthesia and Surgical Outcomes
- Sleep and related disorders
University of Florida
2010-2025
Florida College
2014-2025
North Florida/South Georgia Veterans Health System
2006-2024
Geriatric Research Education and Clinical Center
2024
University of Arizona
2024
University of Pittsburgh
2024
University College London
2024
Park University
2023
Center for Drug Evaluation and Research
2021
University Hospital of North Tees
2013
Abstract Objective CDC guidelines highlight the increased suicide risk associated with abrupt discontinuations of long-term opioid therapy (LTOT). However, evidence on specific dose and duration “thresholds” LTOT for is limited. We aimed to identify trajectories before their association 6-month risk. Methods This retrospective cohort study analyzed 2016-2021 Florida Medicaid claims adult non-cancer beneficiaries discontinuation, defined as having a > 15-day gap in supply after ≥90...
State Medicaid programs have implemented initiatives to expand treatment coverage for opioid use disorder (OUD); however, some still require prior authorizations (PAs) filling buprenorphine prescriptions.To evaluate the changes in OUD among enrollees states that completely removed PA requirements.This retrospective cross-sectional study analyzed immediate and trend on during 2013 2020 associated with removal of requirements using a controlled interrupted time series analysis account...
Increasing gabapentinoid use has raised concerns of misuse and abuse in the United States (US). Little is known about characteristics general clinical practice over time. This cross-sectional study used data from National Ambulatory Medical Care Survey. We examined trends patient prescriber diagnoses associated with US ambulatory care visits involving gabapentinoids for adult 2003 to 2016. Using multivariable logistic regression, we estimated adjusted proportion gabapentinoid-involved among...
Little is known about economic and productivity loss by severity of asthma. We investigate health-care utilization, direct medical costs, indirect costs due to from asthma severity.We conducted a cross-sectional analysis the Medical Expenditure Panel Survey database (2010-2017) patients with aged ≥12 years categorized them into mild, moderate, severe groups based on symptom control medications. Study outcomes included asthma-related absenteeism. used zero-inflated Poisson regression models...
Little is known about opioid and gabapentinoid (OPI-GABA) use duration dose patterns' associations with adverse outcome risks. We examined between OPI-GABA trajectories subsequent drug overdose.
Rural clinical schools and regionally based medical have a major role in expanding the rural workforce. The aim of this cohort study was to compare location practice graduates from University Tasmania School Medicine's larger cities Hobart Launceston (UTAS SoM), with those who spent at least 1 year Clinical smaller regional city Burnie RCS) Australia. Specifically, quantify proportion worked an Australian or remote location, towns within Tasmania.The 2014 locations all UTAS SoM RCS between...
We examined trends in management of headache disorders United States (US) emergency department (ED) visits. conducted a cross-sectional study using 2007−2018 National Hospital Ambulatory Medical Care Survey data. included adult patient visits (≥18 years) with primary ED discharge diagnosis headache. classified medications by pharmacological group: opioids, butalbital, ergot alkaloids/triptans, acetaminophen/nonsteroidal anti-inflammatory drugs (NSAIDs), antiemetics, diphenhydramine,...
years), more likely to be male, and had lower rates of hypertension, congestive heart failure, pulmonary disease, chronic obstructive disease than white or black patients (P < .001for each pairwise comparison) (Table ).Discussion | More 40% Latinos in the Baltimore-Washington, DC metropolitan region who were tested for SARS-CoV-2 positive, a much higher proportion any other racial/ethnic group.While testing inclusion criteria standardized, differential access may have contributed positivity;...
Importance Monoclonal antibodies (mAbs) targeting calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP mAbs) offer effective migraine-specific preventive treatment. However, concerns exist about their potential cardiovascular risks due to CGRP blockade. Objective To compare the incidence of disease (CVD) between Medicare beneficiaries with migraine who initiated anti-CGRP-mAbs vs onabotulinumtoxinA in US. Design, Setting, and Participants This retrospective, sequential cohort...
Background Narcolepsy is linked to adverse cardiovascular disease (CVD) outcomes, but few studies have examined its associations with subclinical CVD, including in children. We assessed the relationship between narcolepsy and CVD hypertension, hyperlipidemia, diabetes, nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Methods Results conducted a retrospective cohort study using MarketScan Commercial Medicare Supplemental databases from January 1, 2005 December 31, 2021. Patients...
Abstract Background/Aims The CLUSTER Champions are a network of patients and parents with lived experience juvenile idiopathic arthritis (JIA). core aim the involvement in Consortium is to create more impactful research. Their insightful perspectives crucial: this has been so highly valued by research team who have listened considered all suggestions. This led improved translational paediatric rheumatology. Champions’ includes study design from initial stages concepts developments throughout...
<sec> <title>BACKGROUND</title> Healthcare providers must carefully monitor patients receiving long-term opioid therapy (LTOT) to minimize risks and maximize benefits. Yet, algorithms support timely intervention during patient encounters are lacking, with accurate LTOT identification in routine care being the essential first step. </sec> <title>OBJECTIVE</title> To develop validate an algorithm using electronic health record (EHR) data. <title>METHODS</title> In this cross-sectional study,...
Abstract Introduction Emerging evidence links narcolepsy to major adverse cardiovascular events (MACE). While typically manifests early in life, it remains unclear whether disease (CVD) also develops early. We hypothesized that elevates the risk of cardiometabolic conditions from childhood into later potentially explaining heightened MACE persons with (PWN). Methods conducted a retrospective cohort study using MarketScan® Commercial and Medicare Supplemental databases (2005-2021). PWN were...
Abstract Introduction Narcolepsy, a chronic neurological sleep disorder, has two subtypes: type 1 (NT1), characterized by cerebrospinal fluid (CSF) orexin deficiency, and 2 (NT2), normal CSF levels. Both subtypes share symptoms, such as excessive daytime sleepiness (EDS) fragmented nocturnal sleep, but cataplexy is specific to NT1. Given orexin’s role in autonomic regulation, NT1 linked cardiometabolic risks. However, data on outcomes limited for both subtypes. Therefore, we assessed the...
Abstract Introduction Emerging evidence suggests narcolepsy is associated with cardiovascular disease (CVD) and major adverse events (MACE). However, its association cardiometabolic disorders, which contribute to elevated CVD risks, remains poorly understood. In this study, we examined whether increased risk of disorders (including hypertension, hyperlipidemia, diabetes) as well MACE. Methods This retrospective cohort study used data from the 2005-2021 MarketScan® Commercial Medicare...