A5052169962- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiovascular Effects of Exercise
- Acute Myocardial Infarction Research
- Cardiac and Coronary Surgery Techniques
- ECG Monitoring and Analysis
- Pulmonary Hypertension Research and Treatments
- Vascular Anomalies and Treatments
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Cancer, Lipids, and Metabolism
- Cell Adhesion Molecules Research
- Ion channel regulation and function
- Vasculitis and related conditions
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Issues in Pregnancy
Ege University
2013-2023
Okan University
2019
Idiopathic ventricular arrhythmias in the form of monomorphic premature contractions (PVC) and/or tachycardia (VT) can cause tachycardia-induced cardiomyopathy (TICMP). The aim this study was to determine incidence, clinical and electrophysiologic characteristics, predictors TICMP patients with idiopathic arrhythmias.Study population consisted 249 consecutive (148 F/101 M, 45 ± 20 y/o) frequent PVCs VT. All underwent transthoracic echocardiography 24-hour Holter monitoring. defined as left...
Background: A subgroup of outflow tract (OT) ventricular tachycardias (VT) originate from the aortic sinuses or main stem pulmonary artery. The anatomic substrate for these is unknown. aim this study was to investigate presence myocardial extensions (VME) into artery (PA) and aorta (Ao) beyond ventriculo‐arterial junction (VAJ) determine anatomical histological characteristics muscle extensions. Methods: Ninety‐five consecutive human hearts obtained at autopsy were studied. Longitudinal...
To determine whether statin therapy initiated early in acute myocardial infarction together with thrombolytic patients results clinical benefit through plaque stabilization.The study population consisted of 77 who underwent coronary balloon angioplasty the infarct-related artery during first month infarction. These belonged to cohort Pravastatin Turkish Trial (PTT). Forty them were assigned randomly have immediate pravastatin (40 mg/day) adjunctive regardless serum lipid levels and received...
Abstract Balloon mitral valvuloplasty with Inoue technique was performed in two group of patients. In I (n = 40) under fluoroscopy without using echocardiography, whereas II 13) the guidance transesophageal echocardiography alone, fluoroscopy. Patients groups were comparable regard to clinical variables and hemodynamic parameters. Two female patients pregnant. Transmitral pressure gradient decrease did not differ significantly between (pressure gradient: 17 ± 5 4 1 15 3 mm Hg II). Mitral...
Frequent, monomorphic premature ventricular contractions (PVC) and/or tachycardia (VT) in patients with structurally normal heart usually arise from the right outflow tract (RVOT). The underlying arrhythmogenic substrate for genesis of RVOT tachycardias is largely unknown. aim this study was to investigate genome-wide transcriptional profiling septal wall and control subjects.Transcriptional Affymetrix 3' IVT microarray analysis (Affymetrix, Santa Clara, CA, USA) performed on endomyocardial...
Familiar hypercholesterolemia (FH) is a genetic disease characterized with extremely high levels of cholesterol leading to premature atherosclerosis. In homozygous individuals (HoFH) cardiovascular events could develop in childhood. this article, long-term clinical experience adult HoFH patients who are followed Department Cardiology, Ege University Faculty Medicine presented.Seventeen (11 females, 6 males) being between the years 2000-2013 were included. All data including characteristics,...
Exercise-based cardiac rehabilitation improves exercise capacity and reduces risk factors. The purpose of this pilot study was to examine the effects a home-based program (HBCEP) on tolerance, serum lipids, self-efficacy in coronary heart disease patients Turkey. Self-efficacy theory provided framework for study's intervention.The design pre-test post-test experimental, randomized assignment.The included 30 participants (HBCEP; mean age=54.7+/-7.8) control (C; age=52.7+/-6.5). Phase II three...
Although beta-blockers are highly effective in the treatment of heart failure (HF), many patients with HF receiving a beta-blocker continue to become decompensated and require hospitalization for worsening HF. Levosimendan dobutamine used manage HF, but their comparative effects on left ventricular (LV) function prescribed unknown.The aim this study was compare levosimendan LV systolic diastolic functions chronic treated chronically carvedilol. Forty who had NYHA class III IV symptoms,...
Atrial arrhythmias, particularly atrioventricular nodal reentrant tachycardia, can coexist with drug-induced type 1 Brugada electrocardiogram (ECG) pattern (DI-Type1-BrP). The present study was designed to determine the prevalence of DI-Type1-BrP in patients accessory pathways (AV-APs) and investigate clinical, electrocardiographic, electrophysiologic, genetic characteristics these patients.One-hundred twenty-four consecutive cases AV-APs 84 controls underwent an ajmaline challenge test...
Idiopathic ventricular arrhythmias commonly refer to tachycardia (VT) and/or frequent/monomorphic premature contractions (PVC) in patients with structurally normal heart. Activation of sympathetic tone has been shown play an important role the provocation and maintenance these arrhythmias. We investigated whether common single nucleotide polymorphisms beta(1) beta(2)-adrenergic receptors are associated idiopathic arrhythmias.A total 143 unrelated presenting were prospectively included a...
Spontaneous or inducible atrioventricular nodal reentrant tachycardia (AVNRT) may coexist with idiopathic ventricular arrhythmias (IVAs). The aim of this study was to determine the incidence and clinical electrophysiologic characteristics patients spontaneous AVNRT among IVAs.Nine hundred eighty-seven consecutive IVA (n = 398), 327), preexcitation syndrome 262) were prospectively included in study.Spontaneous present 36 (9.0%) 398 IVA. most common (97%) mode presentation palpitation due...
Background: Histopathologically, progressive cardiac conduction disease (PCCD) is characterized by fibrosis and sclerodegenerative changes in the proximal distal system of heart. Therefore, we sought to determine serum levels myocardial collagen turnover markers, extracellular matrix components, transforming growth factor β 1 (TGFβ ), bone morphogenic protein‐7 (BMP‐7) this population. Methods: Study population included 20 patients (6 M/14 F, mean age 76 ± 8 years) with acquired, permanent...
Antiarrhythmic drugs remain the first-line therapy for treatment of idiopathic ventricular arrhythmias.The aim this study was to assess therapeutic efficacy extended-release metoprolol succinate (MetS) and carvedilol idiopathic, frequent, monomorphic premature contractions (PVCs).Study population consisted 114 consecutive patients: 71 received MetS 43 carvedilol.All patients underwent 24-hour Holter monitoring at baseline during drug therapy. PVC-burden response categorized as "good" (≥80%...
Although factor V Leiden mutation, is the most common established genetic risk for venous thrombosis, its effect on development of myocardial infarction remains unclear. We describe a family case homozygous mutation in two siblings presenting with acute as rare cause young.
Exercise-based cardiac rehabilitation improves exercise capacity and reduces risk factors. The purpose of this pilot study was to examine the effects a home-based program (HBCEP) on tolerance, serum lipids, self-efficacy in coronary heart disease patients Turkey. Self-efficacy theory provided framework for study's intervention. design pre-test post-test experimental, randomized assignment. included 30 participants (HBCEP; mean age = 54.7 ± 7.8) control (C; 52.7 6.5). Phase II three 45-60-min...