A5042607763- Catalysis for Biomass Conversion
- Catalysis and Hydrodesulfurization Studies
- Catalytic Processes in Materials Science
- Nanoplatforms for cancer theranostics
- Catalysts for Methane Reforming
- Hepatitis C virus research
- Extracellular vesicles in disease
- Hepatitis B Virus Studies
- Nanomaterials for catalytic reactions
- Liver Disease Diagnosis and Treatment
- Gut microbiota and health
- Animal Nutrition and Physiology
- Microbial Metabolism and Applications
- Phagocytosis and Immune Regulation
- Immune cells in cancer
- Selenium in Biological Systems
- Trace Elements in Health
- Catalysis and Oxidation Reactions
- Biofuel production and bioconversion
- Asymmetric Hydrogenation and Catalysis
- Reliability and Maintenance Optimization
- Catalytic C–H Functionalization Methods
- Mesoporous Materials and Catalysis
- biodegradable polymer synthesis and properties
- Membrane-based Ion Separation Techniques
Second Affiliated Hospital of Xi'an Jiaotong University
2021-2025
Zhejiang University
2016-2025
Zunyi Medical University
2024-2025
Xi'an Jiaotong University
2020-2025
Henan Agricultural University
2025
Shenzhen Bay Laboratory
2021-2024
State Key Laboratory of Chemical Engineering
2024
Guangdong Academy of Medical Sciences
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
In many reactions restricted by water, selective removal of water from the reaction system is critical and usually requires a membrane reactor. We found that simple physical mixture hydrophobic poly(divinylbenzene) with cobalt-manganese carbide could modulate local environment catalysts for rapidly shipping product in syngas conversion. were able to shift water-sorption equilibrium on catalyst surface, leading greater proportion free surface turn raised rate conversion nearly factor 2. The...
Copper nanoparticle-based catalysts have been extensively applied in industry, but the nanoparticles tend to sinter into larger ones chemical atmospheres, which is detrimental catalyst performance. In this work, we used dealuminated Beta zeolite support copper (Cu/Beta-deAl) and showed that these particles become smaller methanol vapor at 200°C, decreasing from ~5.6 ~2.4 nanometers diameter, opposite general sintering phenomenon. A reverse ripening process was discovered, whereby migratable...
Immune checkpoint blockade (ICB) has brought tremendous clinical progress, but its therapeutic outcome can be limited due to insufficient activation of dendritic cells (DCs) and infiltration cytotoxic T lymphocytes (CTLs). Evoking immunogenic cell death (ICD) is one promising strategy promote DC maturation elicit T-cell immunity, whereas low levels ICD induction solid tumors restrict durable antitumor efficacy. Herein, we report a genetically edited membrane-coated cascade nanozyme...
The management of myocardial ischemia/reperfusion (I/R) damage in the context reperfusion treatment remains a significant hurdle field cardiovascular disorders. injured lesions exhibit distinctive features, including abnormal accumulation necrotic cells and subsequent inflammatory response, which further exacerbates impairment cardiac function. Here, we report genetically engineered hybrid nanovesicles (hNVs), contain cell-derived overexpressing high-affinity SIRPα variants (SαV-NVs),...
Abstract Dendritic cell (DC) vaccines have shown promising effects in cancer management, while low activity and migration rate to lymph nodes limit their clinical application. Here, this work reports a bioink DC vaccine, synthesized by 3D printing methacryloyl gelatin encapsulate DCs tumor cellular vesicles overexpressing programmed death protein 1 (PD1‐CVs), for immunotherapy. Compared with traditional hydrogel, the porous scaffold significantly improves viability of from ∼16% ∼70% after 7...
The effect of support in Ir-ReOx catalysts for glycerol hydrogenolysis to 1,3-propanediol was investigated. Rutile TiO2 showed high activity, even higher than previously reported SiO2 support. Anatase TiO2, C, ZrO2, CeO2, Al2O3, and MgO supports very low activity supported pairs. Higher Ir-based productivity Ir-ReOx/rutile catalyst obtained at the initial stage with lower Re/Ir ratio (typical Ir loading amount, 4 wt %, nominal 0.25; actual 0.24) without addition H2SO4 that Ir-ReOx/SiO2. over...
Abstract BACKGROUND This study evaluated the effects of dietary zinc oxide nanoparticles (nano‐ZnOs) on growth performance, status, intestinal morphology, microflora population, and immune response in weaned piglets. A total 150 piglets (9.37 ± 0.48 kg) were randomly allotted to five treatments fed with a basal diet (control), or supplemented nano‐ZnOs at 150, 300, 450 mg kg −1 , 3000 ZnO for 21 days. After feeding test, six pigs from control, groups slaughtered. RESULTS Compared supplements...
Herein, we report that genetically programmable fusion cellular vesicles (Fus-CVs) displaying high-affinity SIRPα variants and PD-1 can activate potent antitumor immunity through both innate adaptive immune effectors. Dual-blockade of CD47 PD-L1 with Fus-CVs significantly increases the phagocytosis cancer cells by macrophages, promotes antigen presentation, activates T-cell immunity. Moreover, bispecific targeting design ensures better on tumor cells, but less other which reduces systemic...
The hydrogenation of CO2 to methanol, which is restricted by water products, requires a selective removal from the reaction system. Here, we show that physically combining hydrophobic polydivinylbenzene with copper catalyst supported silica can increase methanol production and conversion. Mechanistic investigation reveals promoter could hinder oxidation surface water, maintaining small fraction metallic species on abundant Cuδ+, resulting in high activity for hydrogenation. Such mixed...
Safe and effective wound healing can be a major clinical challenge. Inflammation vascular impairment are two main causes of inadequate healing.
Food-derived α-glucosidase inhibitory peptides have gained significant interest in treating type 2 diabetes mellitus (T2DM) owing to their favorable safety profiles. Molecular docking combined with molecular dynamics simulation was performed screen from Ginkgo biloba seed cake (GBSC), and two novel (Met-Pro-Gly-Pro-Pro (MPGPP) Phe-Ala-Pro-Ser-Trp (FAPSW)) were acquired. The results of suggested that FAPSW MPGPP could generate stable complexes 3wy1, the electrostatic van der Waals forces...
In this article, a wideband diplexer is proposed based on spoof surface plasmon polaritons (SSPPs). The dispersion properties of the SSPP unit cell are analyzed, which shows that upper/lower cutoff frequency and bandwidth channel filter can be flexibly controlled. Based SSPP-based bandpass (BPF), WR-4 band further developed by space-mapping technique, used to achieve high computational efficiency design accuracy. For demonstration, two BPFs fabricated high-precision computer numerical...
Abstract Trifluoromethyl cationic carbyne (CF 3 C + :) possessing dual carbene‐carbocation behavior emulated as trifluoromethyl metal‐carbynoid =M) has not been explored yet, and its reaction characteristics are unknown. Herein, a novel α‐diazotrifluoroethyl sulfonium salt was prepared used in Rh‐catalyzed three‐component [2+1+2] cycloadditions for the first time with commercially available N ‐fused heteroarenes nitriles, yielding series of imidazo[1,5‐ ] ‐heterocycles that interest...
Cancer nanovaccines have attracted widespread attention by inducing potent cytotoxic T cell responses to improve immune checkpoint blockade (ICB) therapy, while the lack of co-stimulatory molecules limits their clinical applications. Here, a genetically engineered cancer cytomembrane nanovaccine is reported that simultaneously overexpresses molecule CD40L and inhibitor PD1 elicit robust antitumor immunity for immunotherapy. The tumor antigens inherited from cytomembranes effectively...
Abstract The PD1/PD‐L1 immune checkpoint blocking is a promising therapy, while immunosuppressive tumor microenvironment (TME) and poor penetration of therapeutic antibodies limit its efficacy. Repolarization tumor‐associated macrophages (TAMs) offers potential method to ameliorate immunosuppression TME further boost T cell antitumor immunity. Herein, hybrid membrane biomimetic nanovesicles (hNVs) are developed by fusing M1 macrophage‐derived (M1‐NVs) PD1‐overexpressed cell‐derived (PD1‐NVs)...
Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic closely associated with metabolic syndrome, but there are no validated pharmacological therapies. The aim of this study was to investigate effect chitosan oligosaccharide (COS) on NAFLD. Mice were fed either a control diet or high-fat (HFD) without COS (200 400 mg/kg body weight (BW)) by oral gavage for seven weeks. Administration significantly lowered serum lipid levels in HFD-fed mice. hepatic accumulation...