Abstract Purpose To compare lamina cribrosa ( LC ) and choroidal thicknesses using enhanced depth imaging optical coherence tomography EDI ‐ OCT in patients with Parkinson's disease PD healthy controls. Methods A total number of 44 eyes 22 50 25 subjects were utilized this institutional cross‐sectional study. After a complete ophthalmic examination, all imaged RTV ue‐100 version 5.1 Fourier‐domain tomography; Optovue Inc., Fremont, CA, USA); thickness assessed. Results The mean 209.4 ± 40.2...

Tofacitinib, a small molecule pan-JAK inhibitor, targets key inflammatory pathways that play pivotal role in the pathophysiology of uveitis. Its ability to inhibit multiple cytokine signaling makes it promising candidate for treatment ocular inflammation. This study aimed investigate effect oral tofacitinib on peptide-derived S-antigen (PDSAg)-induced chronic experimental autoimmune uveitis (EAU) rats. Nineteen albino Wistar rats were divided into five groups. Groups 1-3 (5 each) immunized...

To report the switch rate of conventional immunosuppressive (CIS) therapies to biological agents (BA) in patients with refractory Behcet's uveitis (BU).In this retrospective study, clinical records were reviewed 76 patients' 116 eyes presenting BU who had been treated drug therapy. Mann Whitney U test was used for intergroup comparisons parameters without normal distribution as well calculation descriptive statistical methods (mean, standard deviation, median, frequency and rate). Wilcoxon...

To identify the causative microorganism of fungal endogenous endophthalmitis in our tertiary referral uveitis center and review therapeutic role pars plana vitrectomy patients with endophthalmitis.Seven eyes six cases were identified as through positive cultures ocular fluids clinical presentations. The final anatomical functional results evaluated.Four women (66.7%) two men (33.3%) underwent vitrectomy. Control infection was achieved early on all cases. Candida (71.4%) Aspergillus (28.6%)...

Purpose: To assess the long-term efficacy and safety of pegylated interferon alpha-2b (peg-IFN-α-2b) for severe uveitis associated with Behçet's disease.Methods: Peg-IFN-α-2b was administrated at an initial dosage 0,5–1,5 µg/kg/week. If any complications were observed, tapered. Ocular examinations, systemic findings, treatment compliance patients evaluated.Results: Control ocular inflammation achieved in all (n = 4). The average increase visual acuity after drug administration 0,425 ± 0,125...

Background . To compare the efficacy and safety of topical anesthesia versus retrobulbar in 23-gauge vitreoretinal surgery. Materials Methods A total 63 patients scheduled for 23 G posterior vitrectomy without scleral buckling procedures were included study. The randomly assigned to receive either (Group 1,<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>31</mml:mn></mml:math>) or 2,<mml:math...

The aim of this study is to determine the incidence retinopathy prematurity (ROP), number preterm infants requiring treatment for ROP, and factors influencing development ROP in a Turkish population.Data on 1,252 who were screened an ophthalmology department retrospectively reviewed. Infants with gestational age (GA) no more than 28 weeks (n = 157) designated group 1, those between 29 32 572) assigned 2, 33 37 523) 3.In was detected 70.0% infants, 17.8% whom required therapy. In 41.4%, 4.0%...

The purpose of this work was to describe the choroidal structure in patients with oculocutaneous albinism (OCA).20 eyes 10 OCA and 14 7 healthy controls were recruited for study. Enhanced depth imaging optical coherence tomography (OCT) images subjects taken. thickness (CT) measured from outer boarder retinal pigment epithelium inner sclera at 500 µm intervals a horizontal section optic disc. Statistical analysis performed evaluate variations CT subfoveal peripapillary areas.In fundoscopic...

Purpose: In this experimental study, the effects of systemic memantine administration on retinal ultrastructure experimentally induced glaucomatous rats were investigated.Methods: Twenty-four Wistar albino included in study.Glaucoma was by injecting sodium hyaluronate into anterior chamber for a period three weeks.As control, 8 sham treated (Group C).Glaucoma animals divided two groups; Group M (n = 8) received single daily dose 10 mg/kg memantine, and G same volume saline 8), via...

A 23-year-old patient presented with complaints of redness, pain, photophobia, and blurred vision in the right eye 15 days after she received third dose BNT162b2 vaccination. Ocular examination revealed 2+ cellular reactions anterior chamber mutton fat keratic precipitate no vitritis or retinal alterations. Active uveitis findings regressed corticosteroid cycloplegic drops. We present a case unilateral granulomatous following vaccination, etiologic factor work-up previous history before This...

Cat scratch disease (CSD) is a syndrome characterized by lymphadenopathy, fever, and skin lesions following cat or bite. Bartonella henselae the primary bacterial agent responsible for CSD. In this report, we describe cases with atypical presentation of serologically proven B. neuroretinitis. study, 3 patients neuroretinitis were evaluated. Animal contact histories; results ocular examinations systemic investigations; clinical findings; treatment compliance assessed. All denied history cats...

Purpose. In here we described cytomegalovirus retinitis (CMVR) in 12-year-old male patient with acute lymphoblastic leukemia (ALL) who was on maintenance phase therapy. Methods. He referred to our clinic for seeing of spots the right eye 3 days. At presentation, his best corrected visual acuity 20/20 and left eye. Slit-lamp biomicroscopic examination anterior chamber within normal limits, whereas observed 3+ cellular reaction On retinal examination, found active lesions (cream-colored...

To investigate factors affecting relapse and remission in patients with Behçet uveitis (BU) the context of using interferon alpha2a (IFNα2a) therapy.Clinical records were reviewed 32 (totaling 54 eyes) presenting severe BU who had been treated IFNα2a therapy. Factors influencing relapsing-remitting course during therapy after cessation agent evaluated. Possible recurrence age, gender, duration disease, time elapsed before starting drug, number relapses IFNα2a, laterality, presence...

To report the fundus photographs and spectral domain optical coherence tomography (SD-OCT) findings of a patient with subacute sclerosing panencephalitis (SSPE) presenting merely ocular symptoms.A 20-year-old presented sudden loss vision in left eye (LE). Fundus photograph showed yellow lesion macula SD-OCT increased reflectivity inner retinal layers. Disorganization necrotizing layers LE gradually progressed to atrophic retina. Then, visual complaints began right (RE) accompanied by...

Purpose The aim of this study was to document diurnal changes in intraocular pressure (IOP) uveitic glaucoma (UG) and compare it with primary open angle (POAG) patients.Methods Eight patients UG seven POAG were included study. matched for age, gender, medications. None the experienced closure, uveitis attack, ocular surgery, not under steroid or immunomodulatory therapy within last three months. 24-hour IOP fluctuations recorded help a contact lens sensor (Sensimed Triggerfish ®,...

Purpose To report and evaluate the incidence risk factors of retinopathy prematurity (ROP) to assess sensitivity specificity Turkish national screening guideline (NSG) in heavier infants with a birth weight (BW) >1500 g.Methods The data 1784 preterm BW>1500 g, who were screened between 2009 2016 university hospital Turkey, analyzed retrospectively. rates any stage severe (treatment-requiring) ROP investigated. possible protective evaluated univariate analyses logistic regression...

To describe the clinical characteristics and late results of patients with retinopathy prematurity (ROP) treated "6h cryotherapy".Out 1252 infants screened for ROP, 52 were temporal 6h cryotherapy from 1997 to 2005 recalled our clinic. Among these 23 available 46 eyes included evaluate visual acuity, refractive error, ocular alignment, nystagmus, retinal examination (abnormal branching vessels, thinning, latis degenerations, tortuosity straightening narrowing angle vessel in juxtapapillary...

Abstract Purpose: To report the effects of anti-vascular endothelial growth factor (VEGF) treatment in vascular development for cases acute retinopathy prematurity (ROP) using fluorescent angiography (FA) and to present results our observational approach retinal sequelae. Methods: A total 31 eyes 19 patients with a history anti-VEGF agents classic type 1 ROP aggressive posterior who underwent FA between March 2014 February 2020 were reviewed. Angiograms developmental features aged 4 months 6...