Zaki F. Aref

ORCID: 0000-0002-1803-735X
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About
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Research Areas
  • Long-Term Effects of COVID-19
  • Obstructive Sleep Apnea Research
  • Olfactory and Sensory Function Studies
  • COVID-19 Clinical Research Studies
  • Vestibular and auditory disorders
  • Nasal Surgery and Airway Studies
  • Advanced Chemical Sensor Technologies
  • Ear Surgery and Otitis Media
  • Tracheal and airway disorders
  • Cleft Lip and Palate Research
  • melanin and skin pigmentation
  • SARS-CoV-2 and COVID-19 Research
  • Helicobacter pylori-related gastroenterology studies
  • Acne and Rosacea Treatments and Effects
  • Voice and Speech Disorders
  • Remote Sensing and LiDAR Applications
  • Teratomas and Epidermoid Cysts
  • Retinoids in leukemia and cellular processes
  • Noise Effects and Management
  • Salivary Gland Tumors Diagnosis and Treatment
  • Vitamin D Research Studies
  • Congenital Ear and Nasal Anomalies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Microscopic Colitis
  • Ophthalmology and Eye Disorders

South Valley University
2017-2023

Sohag University
2019-2020

Misr International University
2020

COVID-19 is a severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2). Deficiency of zinc has been supposed to contribute loss smell and taste in patients. Our study aimed assess the serum levels among patients with various severities, without olfaction dysfunction, evaluate effect therapy recovery dysfunction such This included 134 patients; real-time reverse transcription-polymerase chain reaction (rRT-PCR) proved SARS-CoV-2. Serum were measured for all infected One hundred...

10.1007/s12011-020-02546-5 article EN other-oa Biological Trace Element Research 2021-01-07

Background: Ivermectin is an FDA-approved broad-spectrum anti-parasitic agent that has been shown to inhibit SARS-CoV-2 replication in vitro . Objective: We aimed assess the therapeutic efficacy of ivermectin mucoadhesive nanosuspension intranasal spray treatment patients with mild COVID-19. Methods: This clinical trial included 114 diagnosed as Patients were divided randomly into two age and sex-matched groups; group A comprising 57 received nasal twice daily plus Egyptian protocol for...

10.2147/ijn.s313093 article EN cc-by-nc International Journal of Nanomedicine 2021-06-01

Abstract Evidence on the efficacy of adding macrolides (azithromycin or clarithromycin) to treatment regimen for COVID-19 is limited. We testify whether azithromycin clarithromycin a standard care was superior supportive alone in patients with mild COVID-19.This randomized trial included three groups COVID-19. The group included, 107 who received 500 mg/24 h 7 days, 99 /12 and control only. All only symptomatic fever cough .Clinical biochemical evaluations study participants including...

10.1038/s41598-021-95900-z article EN cc-by Scientific Reports 2021-08-11

Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo. Vitamin D deficiency may be one causes its development. To assess relation between recurrent attacks BPPV and deficiency. A case control study in which 40 patients were clinically diagnosed as posterior canal BPPV, Serum 25(OH) was measured at 1st visit. Patients divided into two groups; group (20 patients) received supplementation addition to repositioning maneuver B treated by only. Follow up all for 6 months,...

10.1038/s41598-021-96445-x article EN cc-by Scientific Reports 2021-08-19

10.1007/s12070-017-1189-z article EN Indian Journal of Otolaryngology and Head & Neck Surgery 2017-08-30

Purpose: Anosmia or hyposmia, with without taste changes, are common symptoms that occur in SARS-CoV-2 infection and frequently persist as post-COVID-19 manifestations. This is the first trial to assess potential value of using local ivermectin form a mucoadhesive nanosuspension nasal spray treat anosmia. Methods: It controlled, randomized trial. Participants were recruited from South Valley University Hospitals Qena, Upper Egypt, ENT Chest Diseases Departments outpatient clinics. Patients...

10.2147/idr.s381715 article EN cc-by-nc Infection and Drug Resistance 2022-09-01

Abstract Background: COVID-19 is a severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2). Deficiency of zinc has been supposed to contribute loss smell, and taste in patients. Our study aimed assess the serum levels among patients with various severities, without olfaction dysfunction. Also, evaluate effect therapy recovery smell dysfunction such Methods : This included 134 patients; real-time reverse transcription- polymerase chain reaction (rRT-PCR) proved SARS-CoV-2....

10.21203/rs.3.rs-107577/v1 preprint EN cc-by Research Square (Research Square) 2020-11-16

Helicobacter pylori is assumed to cause many gastric and extragastric diseases. We aimed assess the possible association role of H. in Otitis media with effusion (OME), nasal polyps adenotonsillitis.A total 186 patients various ear, nose throat diseases were included. The study comprised 78 children chronic adenotonsillitis, 43 65 OME. OME assigned two subgroups: those who have did not adenoid hyperplasia. Among bilateral polyps, 20 individuals had recurrent 23 de novo polyps. Patients...

10.2147/idr.s411867 article EN cc-by-nc Infection and Drug Resistance 2023-06-01

<p><strong>Background:</strong> This study is looking at the daily life consequences of hearing loss in older adults, and how aids (HA) can affect their lives.</p><p><strong>Method:</strong> Everyone who took part had checked using basic tests. The McCarty Alpiner scale a way to measure much personal affection someone has. Arabic international outcome inventory for was used benefits aids.</p><p><strong>Results:</strong> There...

10.18203/issn.2454-5929.ijohns20223291 article EN International Journal of Otorhinolaryngology and Head and Neck Surgery 2022-12-13

Abstract Evidence on the efficacy of adding macrolides (azithromycin or clarithromycin) to treatment regimen for COVID-19 is limited. We testify whether azithromycin clarithromycin a standard care was superior supportive alone in patients with mild COVID-19.The study included three groups COVID-19. The group included, 107 who received 500 mg/24 h 7 days, 99 /12 and control only. All only symptomatic fever cough .Clinical laboratory evaluations participants including assessment symptoms...

10.21203/rs.3.rs-181996/v1 preprint EN cc-by Research Square (Research Square) 2021-02-01

Introduction: Nasopharyngeal mass resembles a confounding problem in adults because of the increased fear malignancy with age advancement. Histopathological pattern nasopharyngeal lesions varies from common benign such as hyperplastic lymphoid tissue and cysts to malignant diseases lymphoma carcinoma. Methods: This prospective study included all patients underwent biopsy for 2 years period October 2014 September 2016. Blind was taken cases clinically suspicious having Patients...

10.4172/2161-119x.1000311 article EN cc-by otolaryngology 2017-01-01

10.62877/56-ijcbs-24-25-19-56 article EN International Journal of Chemical and Biochemical Sciences 2024-01-01

Introduction: Hypertrophy of the inferior turbinate is considered as one major causes chronic nasal obstruction, which sometimes doesn't respond to medical treatment and need surgery. Different surgical techniques have been described for hypertrophy Aim work: This study aimed compare effectiveness safety partial turbinectomy coblation in reduction hypertrophied turbinate. Materials methods: The was conducted Department ENT, Qena faculty medicine South Valley university. Sixty patients with...

10.21608/ejnso.2019.57905 article EN Egyptian Journal of Neck Surgery and Otorhinolaryngology 2019-06-01

Introduction: Several techniques have been used for repairing tympanic membrane perforations starting from chemical cauterization of the edges perforation to use autologous graft materials such as temporalis muscle fascia, perichondrium and cartilage.Aim: To present our approach combined cartilage (button graft) with trichloroacetic acid (TCA) repair small medium sized perforations.Materials Methods: In this study 80 patients TM included divided into two groups.In group button (BG) TCA was...

10.21608/ejnso.2019.57908 article EN Egyptian Journal of Neck Surgery and Otorhinolaryngology 2019-11-01

Objective:The object of this study is to evaluate the relation between 25-hydroxycholecalciferol (vitamin D 3 ) deficiency and allergic rhinitis by detecting level 25-hydroxy cholecalciferol Immunoglobulin E serum levels.Methods: This a case-control in which we compare two groups; group A included 69 patients diagnosed as (AR) B 60 healthy individuals.Serum levels immunoglobulin (IgE) were assessed all participants both groups study.Results: Serum (AR patients) was statistically...

10.21608/svuijm.2020.45265.1014 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2020-10-18

Back ground: the classic surgical technique performed with an adenoid curette or adenotome has recently developed by introduction of endoscopic sinus surgery Objectives: to compare safety and efficacy coblation adenoidectomy versus conventional curettage adenoidectomy.Patients methods: This study was conducted on 50 patients who came outpatient clinics in Otolaryngology department, age group between 4-14 years adenoids hypertrophy from February 2019 2020.Results: results revealed that mean...

10.21608/svuijm.2020.48334.1028 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2020-11-04

Background: Adenoidectomy by conventional method is an old procedure.Several new techniques discovered in this field as electronic molecular resonance, suction diathermy, microdebrider, endoscopy, and laser.Objectives: to assess advantages of endoscopic assessed microdebrider adenoidectomy over the intra post-operative.Patients methods: 218 patients were scheduled for divided into two groups) underwent curettage, group B (106 patients) microdebrider.Follow up 2 weeks ended...

10.21608/svuijm.2020.48686.1033 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2020-11-13

Background: H.pylori is a Gram-negative bacterium known to be associated with peptic ulcer disease, gastric cancer, lymphoma. Recently it was detected in mucosa of patients CRS, but relation bilateral nasal polyposis has not been demonstrated yet. Objectives: H. pyloriis pathogen that lives the gastrointestinal tract (GIT) and extragastric manifestations. Nasal polypi may one these This study aims detect between polypi.  Patients methods: includes 80 cases polypi, 40 them were de novo...

10.21608/svuijm.2021.69625.1151 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2021-06-28

Beta-Hemolytic streptococci are the most frequent bacteria causing tonsillitis. Lactoferrin may play a role in treatment of chronic tonsillitis due to its direct antimicrobial activity.

10.2147/idr.s376401 article EN cc-by-nc Infection and Drug Resistance 2022-09-01

Background: Hearing is the ability to perceive sounds. Usually, range known be between 20 Hz and 20,000 (Hertz). Loss in detect sound levels natural spectrum of hearing referred as disability. Tinnitus, originally defined experience a not connected an external source stimulus.,It complex, reflecting developments cochleovestibular system brain function. Vertigo has been described sense motion when no occurs. In spite wide prevalence audiovestibular complaints worldwide, it studied before...

10.21608/svuijm.2021.54321.1057 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2021-04-11

Background: Sudden sensory neural hearing loss (SSNHL) is an ENT emergency which defined as a of 30 dB or more, over at least 3 successive frequencies, that develops within days in most cases it unilateral and the age group to be affected are 40s 50s cause not known called idiopathic loss. pure tone audiometry done confirm loss, history, examination, MRI blood tests exclude  serious underlying causes .  Objective: compare between efficacy four versus two intra tympanic injection steroid for...

10.21608/svuijm.2021.68849.1140 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2021-04-11

IntroductionA basic description of cholesteatoma is skin in the wrong place with keratin retention; this condition often persists and obviously corrodes internal ear lobe components.(Bassiouni et al., 2017).On other hand, otitis media refers to edema fills middle cavity may complicate meningitis, sinus thrombosis, epidural abscess petrositis (Weissleder 2011).The diagnosis are based on clinical findings, otoscopy otomicroscopy playing a key role .A polyp or granulation tissue cover it,...

10.21608/svuijm.2021.98811.1225 article EN cc-by-nc-sa SVU-International Journal of Medical Sciences 2021-10-23
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