A5073469185- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Neurological Complications and Syndromes
- Dementia and Cognitive Impairment Research
- Aortic aneurysm repair treatments
- Nanoparticle-Based Drug Delivery
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Stress Responses and Cortisol
- Aortic Disease and Treatment Approaches
- Pharmacy and Medical Practices
- CNS Lymphoma Diagnosis and Treatment
- Spatial Neglect and Hemispheric Dysfunction
- Cognitive Functions and Memory
- Immunodeficiency and Autoimmune Disorders
- Atrial Fibrillation Management and Outcomes
- Childhood Cancer Survivors' Quality of Life
- Neuroinflammation and Neurodegeneration Mechanisms
- Infectious Encephalopathies and Encephalitis
Nagasaki Prefectural Shimabara High School
1990-2025
Nagasaki University
2023-2025
Nagasaki Medical Center
2019
Iwate Medical University
2014
Kanazawa University
2009
Nagoya City University
1995-2000
In Japan, many carbon monoxide (CO) poisoning cases are transported to emergency settings, making treatment and prognostic assessment an urgent task. However, there is currently no reliable means predict whether "delayed neuropsychiatric sequelae (DNS)" will develop after acute CO poisoning. This study intended find out risk factors for the development of DNS characterize clinical course following in cases.This a retrospective cohort 79 consecutive patients treated at single institution...
Persistent left superior vena cava (PLSVC) is rare, occurring in approximately 0.3%-0.5% of the population. In endovascular treatment (EVT), internal jugular vein (IJV) approached via innominate from cava; however, occasionally absent patients with PLSVC. Careful consideration required when performing EVT, particularly transvenous embolization (TVE). A 70-year-old female presented a cavernous sinus dural arteriovenous fistula. Left external carotid angiography findings showed that multiple...
Abstract Objective Alzheimer's disease (AD) is a neurodegenerative disorder that the most common cause of dementia in elderly and frequently accompanied by emotional disorder, including agitation. Although evidence neuroendocrine immune inflammatory functions during changes has been accumulated, pathogenic mechanisms development agitation AD remain to be elucidated. Methods To clarify involvement systems AD, we examined levels, circadian rhythms behavior, cortisol, interleukin‐1β (IL‐1β),...
We report a rare case of an unruptured aneurysm arising from the junction between internal carotid artery(ICA)and duplicate origin middle cerebral artery(MCA). A 49-year-old man who presented with vertigo was admitted to our hospital. Subsequent MR and CT angiograms revealed incidental proximal end left MCA. He underwent clipping via distal transsylvian approach. The projected posterior direction several perforators two M1 segments were attached neck aneurysm, which made dissection very...
Abstract INTRODUCTION Primary central nervous system lymphoma (PCNSL) is characterized by an extremely high proliferation rate, making early diagnosis and therapeutic intervention crucial. To facilitate rapid diagnosis, our hospital has implemented flow cytometry (FCM) in addition to conventional histopathological methods. We evaluated the effectiveness of FCM for PCNSL. METHODS From 2010 2023, we retrospectively analyzed 67 consecutive patients with suspected PCNSL based on preoperative...
Abstract Nucleic acid therapeutics hold promise for cancer treatment but have yet to be effectively applied malignant glioma due challenges in stability and delivery. We explored the intracerebral delivery of lipid nanoparticles (LNPs) encapsulating siRNA as a drug carrier. Our goal was develop an therapy selectively targeting cells by combining LNPs with Fc-domain-binding peptide lipids (FcBPs), modification system that allows antibody orientation control. Intracerebral Delivery...
We report an extremely rare case of a fenestration in the cavernous segment left internal carotid artery(ICA)associated with unruptured aneurysm at proximal end fenestrated portion. A 44-year-old woman dull headache was referred to our hospital for further evaluation suspected right ICA on MR angiography(MRA). CT angiography and 3D-rotational revealed no ICA;however, intracavernous incidental observed ICA. The small(5×3mm)with wide neck arising from origin ventral limb duplicated vessels,...
We report a rare case of reversible cerebral vasoconstriction syndrome(RCVS)with cortical subarachnoid hemorrhage(cSAH)associated with fresh infarction beneath the sulcus thick cSAH. A 34-year-old woman presented history thunderclap headache. She was transferred to our hospital for further examination cSAH in left frontal lobe. Results cerebrospinal fluid were unremarkable, but three-dimensional rotational angiography revealed multiple instances narrowing branches anterior and middle...
We report an extremely rare case of dural arteriovenous fistula(DAVF)involving the superior sagittal sinus(SSS)that presented as a primary intraventricular hemorrhage(PIVH). A 79-year-old man who with disturbance consciousness and vomiting was transferred to our hospital. The initial head CT revealed hemorrhage in lateral, third, fourth ventricles, predominantly involving right lateral ventricle associated obstructive hydrocephalus. angiography three-dimensional rotational...
We report an extremely rare case of a fenestration in the infracallosal(A2)segment right anterior cerebral artery(ACA)associated with unruptured aneurysm at proximal end fenestrated portion. A 70-year-old man was referred to our hospital for further examination and treatment aneurysms A1/A2 junction ACA distal vertebral artery that were incidentally detected on MR angiography. CT angiography 3D-rotational revealed A2 segment small(3.6×3.8mm)aneurysm arising from fenestration. The dome...
The incidence of spontaneous thrombosis intracranial aneurysm ranges from 1% to 2% ruptured aneurysms. Most them are giant or large aneurysms, and various factors have been discussed in previous literatures. Recanalization thrombosed aneurysms may be rare, but its mechanism is poorly understood. Reports on recanalization small after the natural history still unknown. We describe a rare case distal posterior inferior cerebellar artery. Spontaneous aneurysmal should not always considered as...
We report an extremely rare case of fenestration the posterior inferior cerebellar artery(PICA)with aneurysm at fenestrated portion. A 60-year-old man with a medical history hemophilia was referred to our hospital for further examination unruptured aneurysms left PICA and vertebral artery(VA)that were incidentally discovered by computed tomography angiography 5 years ago during spontaneous intracerebral hemorrhage. 3D-rotational revealed fenestration(4.7×1.4mm)in anterior medullary segment...
自記式「記憶の質問紙」 (患者用132問,家族用104問) を作成して,健忘患者とその家族に施行し,健忘症状に対する患者の自覚度の障害 (unawareness (UA)) を, (1) 疾患・病巣側性別, (2) 神経心理学的検査成績との相関に焦点をあて,家族の患者の健忘症状に対する評価得点から患者の健忘症状の自己評価得点を引いた値を UA 値として検討した。 対象は54例で,疾患別では,側頭葉てんかん20例,脳血管障害14例, Alzheimer型痴呆 (DAT) 16例,まだ DAT と診断できない変性脳萎縮疾患4例,病巣側性別では,左半球病巣11例,右半球病巣11例,両側半球・び漫性病巣・病巣不明 (BHL) 32例である。 値は,疾患・病巣側性別で有意差 ( と BHL で高値) があり,また右半球損傷を示唆する非言語性記憶検査成績低下などと有意な相関がみられた。したがって, unawarenessは右半球損傷と関連があり,さらに左半球病巣が加わるとより重度となると考えられた。
Objectives Hemodialysis patients have a higher incidence of stroke than healthy individuals. living on remote islands are subject to additional distance and transportation difficulties. Therefore, we aimed study the association between hemodialysis in islands. Materials methods We conducted retrospective cohort based medical records maintenance Shinkamigoto-Cho, Nagasaki, Japan, June 1, 2005, 31, 2022. The clinical characteristics, probability hemorrhagic stroke, acute ischemic stroke-free...
We report a rare case of the endovascular treatment ruptured aneurysm right vertebral artery with an aberrant subclavian artery(ARSA). A 60-year-old woman was urgently admitted because consciousness disturbance. Brain CT showed subarachnoid hemorrhage, and angiography aneurysm. Endovascular performed via transfemoral approach. During treatment, found to diverge from descending aorta on periphery left artery. An ARSA detected, artery(VA)originated ARSA. The guiding catheter passed through VA...
QT延長症候群の既往のある86歳男性，突然倒れこみ救急要請された．橈骨動脈は触知可能であったが，JCS III-200の意識障害と右共同偏視，左上下肢の麻痺を認め，脳卒中疑いで脳神経外科へ搬送．MRI撮影後 JCS II-20，左麻痺も改善．DWIで信号変化はなかったが，右MCA領域にFLAIR vascular hyperintensityを認め，MRAでは右MCAは描出不良であった．脱水があり，当初はこれにより血行力学性に右MCA領域の虚血を来した可能性が考えられた．入院後，心室期外収縮が頻発し，トルサード・ド・ポワント型心室頻拍（VT）が出現した．初回発症時の症状は，VTによる脳虚血症状であったと考えられた．VTによる脳虚血発作は，来院時消失していることがあり，来院時の検査結果で原因が判明しにくい．詳細な病歴聴取が重要であり，特にQT延長症候群の既往がある場合には，VTの可能性を念頭に置く必要がある．