- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Neurological disorders and treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
- Tissue Engineering and Regenerative Medicine
- Cardiomyopathy and Myosin Studies
- Neuroscience and Neural Engineering
- Ion channel regulation and function
- Sarcoidosis and Beryllium Toxicity Research
- Acute Ischemic Stroke Management
- Long-Term Effects of COVID-19
- Obstructive Sleep Apnea Research
- Antimicrobial Resistance in Staphylococcus
- Neuroscience of respiration and sleep
- Infective Endocarditis Diagnosis and Management
- ECG Monitoring and Analysis
The University of Texas Health Science Center at San Antonio
2023-2024
Colorado College
2024
University of Chicago
2014-2023
The University of Texas at San Antonio
2023
University of Chicago Medical Center
2012-2022
University of Illinois Chicago
2014-2022
Boston Scientific (United States)
2021
The Coordinating Center
2019
Geisinger Wyoming Valley Medical Center
2019
Alexian Brothers Medical Center
2008
Septal activation in patients with left bundle-branch block (LBBB) patterns has not been described previously. We performed detailed intracardiac mapping of septal conduction to assess for the presence and level complete (CCB) His-Purkinje system. Response His bundle pacing was assessed without CCB bundle.Left a linear multielectrode catheter consecutive LBBB pattern referred device implantation (n=38) or substrate (n=47). QRS width, duration, His-ventricular (HV) intervals, were analyzed....
Accurate and expedited identification of scar regions most prone to reentry is needed guide ventricular tachycardia (VT) ablation. We aimed prospectively assess outcomes VT ablation guided primarily by the targeting deceleration zones (DZ) identified propagational analysis activation during sinus rhythm.Patients with scar-related were enrolled in University Chicago Ablation Registry between 2016 2018. Isochronal late maps annotated latest local electrogram deflection created high-density...
Background— A proarrhythmic consequence of pulmonary vein (PV) isolation can be a recurrent organized left atrial (LA) tachycardia after ablation. This arrhythmia is frequently referred to as “left flutter,” but the mechanism and best ablation strategy have not been determined. Methods Results— Isolation arrhythmogenic PVs was initially performed by segmental ostial PV guided circular mapping catheter in 341 patients. Patients whose predominant persistent returned for Recurrent LA...
To gain insight into the pathogenesis of right ventricular (RV) cardiomyopathy and tachycardia (VT), we determined clinical electroanatomic characteristics outcome ablative therapy in consecutive patients with (1) RV dilatation, (2) multiple left bundle-branch block (LBBB)-type VTs, (3) an abnormal endocardial substrate defined by contiguous electrogram abnormalities.All 21 had detailed bipolar voltage mapping. Eighteen simultaneous (LV) mapping, including all 4 (RBBB) VT. VT was ablated 19...
Introducton: A 10% incidence of left atrial (LA) thrombus formation has been detected using intracardiac echocardiography (ICE) imaging monitoring during LA ablation for fibrillation (AF). The aim this study was to determine if the intensity anticoagulation reduces pulmonary vein isolation procedure in patients with AF and spontaneous echo contrast (SEC). Methods Results: We studied 511 (age 56 ± 10 years) undergoing ostial isolation/ablation radiofrequency energy. SEC 179 ICE before dual...
The circuit boundaries for reentrant ventricular tachycardia (VT) have been historically conceptualized within a 2-dimensional (2D) construct, with their fixed or functional nature unresolved. This study aimed to examine the correlation between localized lines of conduction block (LOB) evident during baseline rhythm lateral isthmus that 3-dimensionally constrain VT as hyperboloid structure.A total 175 activation maps were correlated isochronal late in 106 patients who underwent catheter...
Active esophageal cooling reduces the incidence of endoscopically identified severe lesions during radiofrequency (RF) catheter ablation left atrium for treatment atrial fibrillation. A formal analysis atrioesophageal fistula (AEF) rate with active has not previously been performed.
<b>Purpose: </b> Proximal aortic atheromas have been suggested as a potential ischemic stroke determinant in the elderly, especially cases of unexplained (cryptogenic) stroke. Our aim was to assess role proximal an independent risk factor for by comparing their frequency patients with acute and stroke-free control subjects. The also compared among different ethnic groups. Patients Methods: A case-control study conducted 106 114 presence portion aorta assessed biplane transesophageal...
Cardiac resynchronization therapy (CRT) or biventricular pacing (BVP) is becoming an important treatment option in patients with severe congestive heart failure (CHF) and electrical dyssynchrony. When combined implantable cardioverter-defibrillator (ICD) therapy, cardiac a defibrillator (CRT-D) has been shown to improve quality of life, functional class, and, most recently, survival. However, left ventricular (LV) stimulation the form BVP at high risk developing tachyarrhythmias raised...
Background: Fast ventricular tachycardias (VTs) have historically been attributed to shorter path lengths with smaller reentrant circuit dimensions in animal models. The relationship between the of VT and tachycardia cycle length (TCL) has not examined humans. This study aimed analyze determinants rate human comparison conduction velocity (CV) across a wide range both stable unstable VTs delineated by high-resolution mapping. Methods: Fifty-four complete delineation (>90% TCL)...
Atrial Pacing in Heart Failure. Introduction: Cardiac resynchronization therapy (CRT) efficacy trials to date used atrial‐synchronous biventricular pacing wherein there is no or minimal atrial pacing. However, bradycardia and chronotropic incompetence are common this patient population. This trial was designed evaluate the effect of support among heart failure patients receiving a CRT defibrillator. Methods Results: PEGASUS multicenter, 3‐arm, randomized study. At 6 weeks, were DDD mode at...
Atypical left atrial flutter (AFL) may be macroreentrant or spatially localized. The relationship between the critical isthmus (CI) for localized reentry with sinus rhythm (SR) conduction slowing has not been systematically examined.