Alessia De Simone

ORCID: 0000-0002-1903-1611
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Liver Disease and Transplantation
  • Organ Transplantation Techniques and Outcomes
  • Brain Metastases and Treatment
  • Gastrointestinal disorders and treatments
  • Estrogen and related hormone effects
  • Breast Lesions and Carcinomas
  • Intensive Care Unit Cognitive Disorders
  • Tuberculosis Research and Epidemiology
  • Diverticular Disease and Complications
  • Clinical Reasoning and Diagnostic Skills
  • Computational Drug Discovery Methods
  • Gastric Cancer Management and Outcomes
  • Clinical Nutrition and Gastroenterology
  • Melanoma and MAPK Pathways
  • Lymphatic Disorders and Treatments
  • Lymphatic System and Diseases
  • Liver Disease Diagnosis and Treatment
  • Renal Transplantation Outcomes and Treatments
  • Medical Case Reports and Studies
  • Prostate Cancer Treatment and Research
  • Colorectal and Anal Carcinomas
  • Inflammatory Bowel Disease
  • Growth Hormone and Insulin-like Growth Factors
  • Glioma Diagnosis and Treatment

Istituti di Ricovero e Cura a Carattere Scientifico
2001-2019

Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2019

Vita-Salute San Raffaele University
2019

Italian Society of Physiotherapy
2013

Fondazione Salvatore Maugeri
2012

Istituti Clinici Scientifici Maugeri
2006-2008

Ospedale Maggiore
2001

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2001

Gruppo Italiano per il Trapianto di Midollo Osseo
2000

Five-year data of the phase III trial TAM-01 showed that low-dose tamoxifen at 5 mg once daily administered for 3 years in women with intraepithelial neoplasia (IEN) reduced by 52% recurrence invasive breast cancer or ductal carcinoma situ (DCIS), without additional adverse events over placebo. Here, we present 10-year results.We randomly assigned 500 IEN (atypical hyperplasia, lobular [LCIS], hormone-sensitive unknown DCIS) to placebo after surgery irradiation. The primary end point was...

10.1200/jco.22.02900 article EN Journal of Clinical Oncology 2023-03-14

Lipofilling is becoming part of the breast reshaping after quadrantectomy or mastectomy in cancer patients, but there are open questions its safety.

10.1016/j.breast.2012.09.011 article EN cc-by-nc-nd The Breast 2012-10-22

Introduction . Pediatric malaria, even in countries considered as free Italy, is an important problem of public health because children have a high variability the clinical picture. The objective this brief note to determine incidence pediatric malaria Piedmont Region during period 1989-2015. Materials and methods All cases notified were thanks regional information flow over Cases congenital unconfirmed cases, aged 14 older excluded study. Results In 1989-2015, accounts for 8.8% total...

10.4415/ann_20_01_11 article EN Annali dell Istituto Superiore di Sanità 2020-03-25

S280 2nd ESTRO Forum 2013 Figure 1: a) Effective doses and b) LYL-ratios. Conclusions:The LYL attributable to cancer therapy were orders of magnitudes larger than the diagnostic scans used for radiotherapy planning.However, uncertainty in present estimates considerable, would benefit from more exact risk models.

10.1016/s0167-8140(15)33047-4 article EN cc-by-nc-nd Radiotherapy and Oncology 2013-03-01

Abstract We have previously shown in a phase 3 trial that tamoxifen 5 mg/day for years decreased by 52% the incidence of recurrence invasive breast cancer or DCIS after median follow-up 5.1 women with excised non disease, including atypical ductal hyperplasia, LCIS (DeCensi et al. JCO 2019; 37:1629). Toxicity was negligible only an extra hot flash per day arm compared placebo arm. These findings were incorporated into ASCO clinical practice guidelines risk reduction as alternative option to...

10.1158/1538-7445.sabcs22-gs4-08 article EN Cancer Research 2023-03-01

Caccamo, Lucio1; Simone, Alessia De1; Rossi, Giorgio1; Reggiani, Paolo1; Gatti, Stefano1; Maggi, Umberto1; Fassati, Luigi R.1 Author Information

10.1097/00007890-200004271-00250 article EN Transplantation 2000-04-01
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