James Gerard Hehir

ORCID: 0000-0002-1921-4071
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Chromosomal and Genetic Variations
  • Mycotoxins in Agriculture and Food
  • Plant-Microbe Interactions and Immunity
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Pathogens and Fungal Diseases
  • Genetics and Plant Breeding
  • CRISPR and Genetic Engineering
  • Fungal Plant Pathogen Control
  • Genomics and Phylogenetic Studies
  • Plant tissue culture and regeneration
  • Plant Genetic and Mutation Studies
  • Fungal and yeast genetics research

Teagasc - The Irish Agriculture and Food Development Authority
2017-2020

Receptor-like kinases form the largest family of receptors in plants and play an important role recognizing pathogen-associated molecular patterns modulating plant immune responses to invasive fungi, including cereal defences against fungal diseases. But hitherto, none have been shown modulate wheat response economically Fusarium head blight (FHB) disease small-grain cereals. Homologous genes were identified on barley chromosome 6H (HvLRRK-6H) 6DL (TaLRRK-6D), which encode characteristic...

10.3389/fpls.2018.00867 article EN cc-by Frontiers in Plant Science 2018-06-26

Zymoseptoria tritici is the causative fungal pathogen of septoria blotch (STB) disease wheat (Triticum aestivum L.) that continuously threatens crops in Ireland and throughout Europe. Under favorable conditions, STB can cause up to 50% yield losses if left untreated. commonly controlled with fungicides; however, a combination Z. populations developing fungicide resistance increased restrictions on use EU has led farmers relying fewer active substances. Consequently, this serves drive...

10.3390/genes11080887 article EN Genes 2020-08-04

Understanding the nuances of host/pathogen interactions are paramount if we wish to effectively control cereal diseases. In case wheat/Zymoseptoria tritici interaction that leads Septoria blotch (STB) disease, a 10,000-year-old conflict has led considerable armaments being developed on both sides which not reflected in conventional model systems. Taxonomically restricted genes (TRGs) have evolved wheat better allow it cope with stress caused by fungal pathogens, and Z. specialised effectors...

10.3389/fpls.2020.00433 article EN cc-by Frontiers in Plant Science 2020-05-07

Zymoseptoria tritici , the causal agent of septoria blotch ( STB ), remains a significant threat to European wheat production with continuous emergence fungicide resistance in Z. strains eroding economic sustainability systems. The life cycle is characterized by presymptomatic phase (latent period, LP ) after which pathogen switches an aggressive necrotrophic stage, when lesions bearing pycnidia quickly manifest on leaf. As minimal knowledge possible role supporting resistance/susceptibility...

10.1111/ppa.12780 article EN Plant Pathology 2017-08-23

The rapid advancement of large-scale genome sequencing projects has opened new avenues for the application conventional mutation techniques in not only forward but also reverse genetics strategies. Targeting induced local lesions genomes (TILLING), developed as an alternative to cumbersome insertional mutagenesis, takes advantage classical sequence availability and high throughput screening nucleotide polymorphisms a targeted sequence. Since it is readily applicable most plants, remains...

10.1201/9781315213743-15 article EN 2017-12-22
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