- Pharmaceutical and Antibiotic Environmental Impacts
- Pesticide and Herbicide Environmental Studies
- Semiconductor materials and devices
- Catalytic Processes in Materials Science
- Advancements in Transdermal Drug Delivery
- Genomics, phytochemicals, and oxidative stress
- Nematode management and characterization studies
- Analytical chemistry methods development
- Electron and X-Ray Spectroscopy Techniques
- Insect-Plant Interactions and Control
- Moringa oleifera research and applications
- Weed Control and Herbicide Applications
- Legume Nitrogen Fixing Symbiosis
- Ion-surface interactions and analysis
- Free Radicals and Antioxidants
- Potato Plant Research
- Phytochemicals and Antioxidant Activities
- Microbial Metabolites in Food Biotechnology
- Plant Parasitism and Resistance
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Lipid Membrane Structure and Behavior
- Bee Products Chemical Analysis
- Dermatology and Skin Diseases
- Microbial bioremediation and biosurfactants
Institute of Bioorganic Chemistry
2019-2025
University of Wisconsin–Madison
2022-2024
University of Idaho
2014-2022
National University of Food Technologies
2020
University of California, Davis
2013-2018
Oklahoma State University
2009-2017
Lomonosov Moscow State University
2004-2016
Plekhanov Russian University of Economics
2016
Moscow State University
2016
Thuyloi University
2013
Changes in the microbial community structure are observed individuals with intestinal inflammatory disorders. These changes often characterized by a depletion of obligate anaerobic bacteria, whereas relative abundance facultative Enterobacteriaceae increases. The mechanisms which host response shapes structure, however, remain unknown. We show that nitrate generated as by-product conferred growth advantage to commensal bacterium Escherichia coli large intestine mice. Mice deficient inducible...
Although mustards such as Sinapis alba and Brassica juncea contain glucosinolates (sinalbin sinigrin, respectively) that hydrolyze to form biopesticidal products, routine quality control methods measure active ingredients in seed meals are lacking. We present a simple fast ion chromatography method for the simultaneous quantification of sinalbin, anionic hydrolysis products mustard assess biological potency. Optimum conditions include isocratic elution with 100 mM NaOH at flow rate 0.9...
The aim of this project was to examine the effect microneedle rollers on percutaneous penetration tiagabine hydrochloride and carbamazepine across porcine skin in vitro. Liquid chromatography-mass spectrometric analysis carried out using an Agilent 1200 Series HPLC system coupled G1969A TOF-MS system. Transdermal flux values drugs were determined from steady-state portion cumulative amount versus time curves. Following twelve hours roller application, there a 6.74-fold increase (86.42 ±...
The use of veterinary pharmaceuticals in beef cattle has led to concerns associated with the development antibiotic resistance bacteria and endocrine disruption aquatic organisms. Despite potential negative consequences, data on transport mitigation grazed watersheds irrigated pasture are scarce. objective this study was assess common (oxytetracycline, chlortetracycline, ivermectin) via surface runoff leachate from manure amended grass-vegetated soil boxes under conditions. animal relatively...
Agricultural practices are increasingly incorporating recycled waste materials, such as biosolids, to provide plant nutrients and enhance soil functions. Although biosolids benefits soil, municipal wastewater treatment plants receive pharmaceuticals heavy metals that can accumulate in land application of transfer these contaminants the soil. Environmental exposure may adversely affect wildlife, disrupt microbial communities, detrimentally human health through long-term exposure, cause...
We show that the electrostatic charging of an aluminum oxide film by electron-bombardment produces a greatly enhanced rate Al(111) oxidation O2(g) at 90 K, compared to which has not been bombarded electrons. This novel memory effect for prior electron irradiation is caused negative potential created and stored on outer surface as result bombardment. The high field ( approximately 10(7) V/cm) produced across depth postulated cause enhancement ion migration through film, leading rapid growth,...
Plant defenses often mediate whether competing chewing and sucking herbivores indirectly benefit or harm one another. Dual-guild herbivory also can muddle plant signals used by specialist natural enemies to locate prey, further complicating the net impact of herbivore-herbivore interactions in naturally diverse settings. While dual-guild herbivore communities are common nature, consequences for top-down processes unclear, as chemically mediated tri-trophic rarely evaluated field...
glycoalkaloids are gaining increased scientific attention due to their bioactive potential in the defense of plants against pests and pathogens. The comprehensive glycoalkaloid profiling from leaves, stems, roots seven underexploited
Infection with phytoviruses influences plant responses to environmental stress, but the biochemical mechanisms underlying these interactions are unknown. of wheat (Triticum aestivum) a cereal virus (Barley yellow dwarf virus, BYDV) has context-dependent effects on productivity and survival conditional water we hypothesized this was due phythormone induction resulting from infection. We tested whether BYDV infection availability interact influence hormone profiles in across multiple time...
The effect of chain length on the low-energy vibrations alkanethiol striped phase self-assembled monolayers Au(111) was studied. We have examined vibrational structure well-ordered, low-density 1-decanethiol (C10), 1-octanethiol (C8), and 1-hexanethiol (C6) to further understand interaction between adsorbate substrate. Dispersionless Einstein mode phonons, polarized perpendicularly surface, were observed for phases C10, C8, C6 at 8.0, 7.3, 7.3 meV, respectively. An overtone 12.3 meV also...
The effect of stainless steel microneedle arrays and rollers on transcutaneous flux captopril metoprolol tartrate across full thickness porcine skin was studied. Captopril is an angiotensin converting enzyme (ACE) inhibitor used for the management hypertension. It has a partition coefficient (log P) 0.35 molecular weight 216.7 g/mol. Metoprolol β-adrenergic blocker also log P 1.6 267.3 properties these anti-hypertensive agents limit amount drugs that can cross skin. To overcome this...
Abstract The eradication program for the potato cyst nematode (PCN), Globodera pallida , in Northwest of United States revolves around use soil fumigation. Alternative, integrated strategies are needed to continue battle this invasive nematode. Laboratory, greenhouse, and field experiments were conducted with G. another found States, ellingtonae evaluate efficacy a new formulated Brassica juncea seed meal extract, as well traditional B. meal, alternate strategies. This is first report on...