A5111858918- Iron Metabolism and Disorders
- Fish biology, ecology, and behavior
- Turtle Biology and Conservation
- Hemoglobinopathies and Related Disorders
- Ichthyology and Marine Biology
- Leprosy Research and Treatment
- Fish Biology and Ecology Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Amphibian and Reptile Biology
- Methemoglobinemia and Tumor Lysis Syndrome
- Kruppel-like factors research
- Business and Management Studies
- Leech Biology and Applications
- Tuberculosis Research and Epidemiology
- Blood disorders and treatments
- Venomous Animal Envenomation and Studies
- Academic Research in Diverse Fields
- Erythrocyte Function and Pathophysiology
- Advanced materials and composites
- Mycobacterium research and diagnosis
- Chronic Myeloid Leukemia Treatments
- Child Nutrition and Water Access
- Education Pedagogy and Practices
- Advanced ceramic materials synthesis
- Heavy Metal Exposure and Toxicity
Universidade de São Paulo
2008-2022
Universidade Federal do Paraná
2022
Sciences and Education Research Council
2022
Universidade Nove de Julho
2018
Universidade Federal de Uberlândia
2001-2015
SUPERA Park of Innovation and Technology of Ribeirão Preto
2003-2015
Universidade de Ribeirão Preto
2004-2014
Universidade Estadual de Ponta Grossa
2010-2013
Universidade Federal de Santa Maria
2011
Universidade Federal de Goiás
2010
Background: Periodontal disease has been associated with many chronic inflammatory systemic diseases, and a common inflammation pathway suggested for these conditions. However, few studies have evaluated whether periodontal disease, in the absence of other known conditions smoking, affects circulating markers inflammation. This study compared control individuals patients observed non‐surgical therapy affected after 3 months. Methods: Plasma serum 20 controls 25 were obtained prior to months...
Abstract The aim of this work was to study the simultaneous heat and mass transfer between air soybean seeds in concurrent moving bed dryers. stationary behaviour process described by energy equations applied both fluid particulate phases, assuming uniform velocity flat profile air. results fluid-dynamic confirmed that inlet profiles were essentially uniform. experimental data simulated values temperature moisture good agreement.
The aim of this work was to evaluate the hematological changes induced by Tityus serrulatus venom (TsV). Blood Wistar rats collected 0.5, 2, 6 and 24 h after i.p. injection TsV (0.5 mg/kg) or saline (controls). Two additional groups were injected with 0.67 mg/kg 0.25 blood 0.5 2 h, respectively. results showed an increase on hematocrit (Ht), red cells (RBC) count, hemoglobin concentration (Hb), albumin total protein, mainly 2-6 envenoming. Increase in serum activities amylase, creatine...
Background Chronic myeloproliferative disorders (MPDs) are clonal haematopoietic stem cell malignancies characterised by an accumulation of mature myeloid cells in bone marrow and peripheral blood. Deregulation the apoptotic machinery may be associated with MPD physiopathology. Aims To evaluate expression death receptors' family members, mononuclear apoptosis resistance, JAK2 allele burden. Subjects Methods Bone progenitor CD34 were separated using Ficoll-hypaque protocol followed Miltenyi...
The thalassemia syndromes (α- and β-thalassemia) are the most common frequent disorders associated with ineffective erythropoiesis. Imbalance of α- or β-globin chain production results in impaired red blood cell synthesis, anemia, more erythroid progenitors stream. While patients affected by these show definitive altered parameters related to erythropoiesis, relationship between degree dysfunctional iron metabolism has not been investigated both α-thalassemia carriers (ATC) β-thalassemia...
<b><i>Background/Aims:</i></b> We investigated the effects of tyrosine kinase inhibitors (TKIs) on expression apoptosis-related genes (BCL-2 and death receptor family members) in chronic myeloid leukemia (CML) patients. <b><i>Methods:</i></b> Peripheral blood mononuclear cells from 32 healthy subjects 26 CML patients were evaluated before after treatment with imatinib mesylate (IM) dasatinib (DAS) by quantitative PCR....
Apoptosis deregulation might have a role in the pathophysiology of polycythemia vera (PV). This study evaluated Bcl-2 molecule expression CD34+ cells and leukocytes 12 PV patients. Gene was investigated by real time PCR using SybrGreen Quantitect kit protein western-blotting. JAK2 V617F mutation detected according to Baxter et al (2005). from patients presented higher levels A1 Mcl-1 (median: 22.6 5.2, respectively) comparison with controls (0.9 0.5, p=0.004 p=0.020); while Bcl-xL decreased...
The feeding behavior and the food preference was studied in P. expansa (Schweigger, 1812) unifilis (Troschel, 1848) sextuberculata (Cornalia, 1849). method used for sampling of all occurrences. Students' t test applied on items, to compare differences during development each species. main conclusions are: food, except alive animals, is divided foraging, approach, olfactory recognition, capture, laceration ingestion; persecution observed prey activity; cleptoparasitism occurs three species...
This study presents data on the reproduction of Abudefduf saxatilis, a rocky shore inhabitant at northern coast São Paulo State. A total 73 individuals were collected using hooks and baits. They measured, weighed dissected, sex maturation stage analysed, first macroscopically, then part material was taken for microscopical confirmation. Visual censuses also done underwater observation egg's presence. Results showed equivalence males females in population, occurring between 101 115mm length,...
Very few studies have investigated, in the elderly, effect of rheumatic inflammatory states on phagocyte function and free radical production. The objective this article is to evaluate phagocytosis by neutrophils production nitric oxide (·NO) monocytes elderly women recruited among patients Brazilian Public Health System.Forty aged more than 60 years with diseases were studied. Phagocytosis was measured flow cytometry. ·NO total nitrite assay conventional inflammation markers determined....
The trace mineral trivalent chromium (Cr 3+ ) is an essential nutrient involved in the regulation of carbohydrate, lipid and protein metabolism via enhancement insulin action.The present work had as objective to characterize histopathologically histometrically hepatic alterations female Wistar rats, determined by III administration drinking water.Adult rats received ration water ad libitum containing 300 or 500 mg/l during 4 months.Control animals only ration.All were sacrificed lethal dose...
Avaliaram-se os efeitos do uso de diferentes níveis salinidade da água irrigação (S1 = 0,55 dS/m, S2 1,70 S3 2,85 dS/m e S1 4,00 dS/m) no crescimento vegetativo bananeiras Pacovan (AAB) Marmelo (ABB), utilizando-se um solo Argissolo Crômico, textura franco-argilo-arenosa adotando-se delineamento experimental em blocos completos casualizados, com parcelas subdivididas quatro repetições. As experimentais foram compostas uma fileira 10 plantas, sendo cinco cada cultivar, as três plantas...
Com os avanços terapêuticos que incluem o mesilato de imatinibe, transplante medula óssea e a infusão linfócito do doador, perspectiva vida dos portadores leucemia mielóide crônica (LMC) tem aumentado significativamente doença pode não ser fatal. No entanto, mecanismos biológicos privilegiam seleção das células hematopoéticas malignas sobre as normais na LMC, responsáveis pelo insucesso terapêutico em muitos casos, ainda estão totalmente esclarecidos. Alterações no processo apoptose celular...
Drug idiosyncrasy is an adverse event of unknown etiology that occurs in a small fraction people taking drug. The histamine-2 (H2)-receptor antagonist ranitidine causes idiosyncratic reactions patients. To investigate the hypothesis could induce hematological toxic effects, drug was administered intraperitoneally (ip) to two six groups 200-220 g male Wistar rats (n=6). Group I received as single dose saline solution (NaCl, 200 µL) II µL NaCl, ip, at 0, 24, 48 and 72 h, III (controls vehicle)...
O plumbismo é um problema de saúde pública, afetando o desenvolvimento das crianças. sistema hematológico alvo importante da toxicidade do chumbo, comprometendo a síntese heme e consequentemente causando anemia. Os efeitos sobre ácido amino levulínico dehidratase (ALAD) são mais marcantes provocando acúmulo (ALA) aumento gama aminobutírico (GABA) no nervoso central. A intoxicação chumbo afeta também cadeias globulínicas α β , que contribui para anemia não uma manifestação precoce plumbismo,...
Sintering in two-steps has been applied with success for densification of nanometric and submicrometer ceramic powders without grain growth. In this work the applicability two-step sintering as a means suppressing growth alumina is verified. Experiments, which were characterized after conventional sintering, conducted. Conventional used choice steps sintering. first studied, one hypothesis that maximization final density minimum can be achieved by improving narrowing size distribution at...