LoF (loss-of-function) mutations causing hereditary abnormalities and embryonic mortality are one of the reasons for a decline in fertility cows. Currently, more than fifteen known Holsteins. In our work, we studied frequency FANCI, APAF1, SMC2, GART, APOB genes that associated with haplotypes HH0, HH1, HH3, HH4, HCD Russian Holstein cattle population. We analyzed estimated breeding values (EBVs) daughters' milk production reproduction traits sires carrying compared to non-carrier using BLUE...

In modern molecular biology and genetics, the study of gene expression plays a key role in understanding mechanisms development functioning living organisms. pig farming, where breeding genetics are important tools for improving animal productivity resilience, analysis can provide valuable material programs. The article devoted to determining TNFAIP3, CDS1 MTAP genes population large white pigs is an in-depth field breeding. above-mentioned were selected connection with their supposed...

Analysis of ancient and historical DNA has great potential to trace the genetic diversity local cattle populations during their centuries-long development. Forty-nine specimens representing five breeds (Kholmogor, Yaroslavl, Great Russian, Novgorod, Holland), dated from end 19th century first half 20th century, were genotyped for nine polymorphic microsatellite loci. Using a multiple-tube approach, we determined consensus genotypes all samples/loci analysed. Amplification errors, including...

Distal occlusion (DO) is one of the most prevalent malocclusions in sagittal plane, accounting for approximately 13 to 31.3% all dentofacial anomalies. Currently, there are nearly 200 methods analyzing lateral cephalometric radiographs, along with numerous supplementary techniques. Conducting a comparative analysis radiographs using A.M. Schwarz and J. Jarabak allows more detailed diagnosis distal differentiation its various forms. This approach not only facilitates objective but also aids...

The comparative molecular genetic study of museum and modern representatives cattle breeds can help to elucidate the origin maintenance historical components in populations. We generated consensus genotypes for 11 microsatellite loci 24 samples Kalmyk, Kyrgyz, Kazakh cattle, dated from first quarter 20th century, compared them with those white-headed breeds. level diversity Kalmyk Kyrgyz (uHe = 0.771–0.778) was similar observed 0.772–0.776), while a visible decrease variability breed...

The myostatin gene (MSTN) in cattle has a number of polymorphisms associated with increased muscle mass. aim the current study was to determine haplotype frequencies F94L and nt821(del11) MSTN among bred for meat Russia, using DNA analysis. Using earlier created test systems based on AS-PCR PCR-RFLP methods, six populations Aberdeen Angus (n = 684), two Limousin 54), one population Simmental 55), Belgian Blue 137) belonging Russian farms were genotyped F94LMSTN polymorphisms. animal carriers...

Poaching is one of the major types wildlife crime in Russia. Remnants goats (presumably wild endemic species, Caucasian tur) were found an area mountains. The case study involves a suspected poacher whose vehicle was to have two duffel bags containing pieces carcass, which he claimed that goat from his flock. aim forensic genetic analysis for this (i) establish individual identity and (ii) perform species identification. DNA typing based on fourteen microsatellites revealed STR-genotypes...

Pig farming is one of the leading branches animal husbandry, in which progressive production technologies are constantly being introduced modern selection methods. With intensive pork technology, requirements for pigs reproductive, fattening and meat productivity increase. Breeding work pig farms mainly focused on improving these productive qualities pigs. The aim this was to develop a comprehensive system assessing breeding value traits Large White using index.

The Dagestan Mountain (DM) cattle breed was established to provide cheese and milk products mountain dwellers in the specific conditions of Republic Southern Russia. Only 650 head DM were registered 2020, their “breed purity” is questionable. We aimed assess genetic diversity population structure modern using short tandem repeat (STR) markers. sample included 150 animals collected from private owners during a scientific expedition (n = 32) provided by gene pool farm 118). An additional 166...

Для совершенствования продуктивных качеств холмогорской породы крупного рогатого скота, характеризующейся неприхотливостью и высокими адаптационными качествами, активно используется голштинизация. Данный процесс может привести к поглощению утрате оригинального генофонда без своевременной оценки генетического состояния по ДНКмаркерам. Целью нашей работы стала генетическая характеристика аллелофонда популяций с помощью STRмаркеров. Исследования проведены на 289 животных, включая генофондные...

Changes in the accuracy of genomic estimates obtained by ssGBLUP and wssGBLUP methods were evaluated using different reference groups. The weighting procedure’s reasonableness application Pwas considered to improve predictions for meat, fattening reproduction traits pigs. Six groups formed assess data quantity impact on predicted values (groups genotyped animals). datasets included 62,927 records meat productivity (fat thickness over 6–7 ribs (BF1, mm)), muscle depth (MD, mm) precocity up...

The domestic insurance market can be described as a complex system of interconnections between entities. Modern events give rise to new challenges and threats the functioning development Ukraine. Therefore, despite existence number publications in sphere market, study this issue should systematic, since balanced operation has significant impact on entire economic state whole. In research process, authors considered interpretation scientists practitioners determine essence concept «insurance...

Preserving biodiversity is a global problem that was reflected in the Convention on Biological Diversity which appeared 1992. The adoption of an answer to intensified significant reduction diversity genetic resources. Botanical gardens are main centres for preserving plants solve gene pool. One tasks botanical monitor plant populations their natural habitats situ. This paper describes monitoring current state peonies and sedges Semistozhki area Andropov district Stavropol region. research...

The object of the study was sires Black-and-White and Holstein breeds, which had STR profiles passed genotyping procedure for SNP markers. subject level genomic inbreeding homozygosity, as well population-genetic characteristics based on them. With an increase in Fx pedigree data, (FROH) calculated from markers also noted. results 9 record a wavelike homozygosity group I to IV with subsequent V VII inclusive. During average FROH values accordance years birth sires, significant difference...

Abstract The article highlighted the problem of genetic defect Aberdeen Angus cattle. Previous investigation showed presence in Russian population cattle animals carrying their genotypes mutant alleles associated with Arthrogriposis multiplex, Developmental Duplication and Osteopetrosis. In some populations, frequencies animals-genetic defects carriers were sufficiently high. aim study was to evaluate risk spread causing disorders by transfer from parents offspring under absence control over...

На примере популяции голштинизированного чернопестрого и голштинского скота, а именно быковпроизводителей, используемых на территории Московской области, было проведено ретроспективное исследование, направленное определение уровня гомозиготности по STRмаркерам, с последующей оценкой влияния основные хозяйственнополезные качества племенную ценность животных. Произведен расчет генетических дистанций индекса фиксации учетом страны происхождения, породной линейной принадлежности в исследуемой...

Abstract. The use of specialized meat breeds in cattle breeding programs is considered very promising for improving herds' productivity. However, animal genotype, along with genes that positively affect the productivity signs, there are whose mutations, known as genetic defects, negatively health animals. aim study was screening Russian populations Aberdeen Angus, Hereford and Belgian Blue on gene mutations associated defects arthrogryposis multiplex (AM), osteopetrosis (OS), developmental...

Relevance . Currently, the development of molecular and population genetics is a relevant task. The need to identify reliable candidate genes associated with increase in pig quality improvement both breeding meat products. In this regard, whole-genome analysis method solves issues genetic determination quantitative economically important traits. Methods study, GWAS was applied reproductive traits Landrace sows. Results 35 biological functionality were identified described, located near or...

The main goal of this study was to determine the genetic parameters reproductive traits in a population Large White pigs, particular, birth weight piglets, weaning number live-born and stillborn mummified litter. We identified 162 significant SNPs, which 6 were common for traits. Functional annotation by biological functions (GO) 12 candidate genes, among special attention should be paid ADCY5 gene, has previously demonstrated an influence on abilities other agricultural animal poultry species.

Currently, genome-wide association analysis is a modern and reliable method for analyzing genomic information about animals, as well determining the “genotype — phenotype” relationship. This study aims to use GWAS identify significant SNPs located within or linked genes meat traits in Large White pigs backfat thickness over 6–7th 10–12th vertebrae, loin muscle depth. The conducted GWA revealed 60 genes, of which 17 are associated with biological functionality, annotated using DAVID program....

Relevance. In pig husbandry, one of the main issue in selection and breeding work is efficiency increasing yield quality products. The development molecular genetic research methods using chips various densities subsequent genome-wide association studies made it possible to identify a large number new genes potentially associated with selectively significant traits. Some these potential are TNFα-induced protein 3 (TNFAIP3) CDP-diacylglycerol synthase 1 (CDS1) genes. results domestic foreign...

Purpose: to summarise the results of genetic diversity studies European bison (Bison bonasus) using microsatellite analysis method. Materials and methods . NCBIs PubMed Database (https://pubmed.ncbi.nlm.nih.gov/) scientific electronic library eLIBRARY.RU (https://elibrary.ru/). Results. Many have been devoted maintenance bison. To date, most in field based on evaluation pedigree data use nuclear mitochondrial markers. Assessment population structure, control inbreeding level captive-bred...