- Ultrasound Imaging and Elastography
- Ultrasound and Hyperthermia Applications
- Ultrasonics and Acoustic Wave Propagation
- Bone health and osteoporosis research
- Ultrasound in Clinical Applications
- Photoacoustic and Ultrasonic Imaging
- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Bone and Joint Diseases
- Seismic Imaging and Inversion Techniques
- Elasticity and Material Modeling
- Microwave Imaging and Scattering Analysis
- Thermal Regulation in Medicine
- Diagnosis and Treatment of Venous Diseases
- Lung Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Preterm Birth and Chorioamnionitis
- Advanced X-ray and CT Imaging
- Phonocardiography and Auscultation Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Adrenal Hormones and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Underwater Acoustics Research
- Pressure Ulcer Prevention and Management
- Radiology practices and education
North Carolina State University
2016-2025
University of North Carolina at Chapel Hill
2017-2024
Centre Hospitalier Universitaire de Grenoble
2003-2024
Université de Lorraine
2020-2024
American Kennel Club Canine Health Foundation
2024
Topcon (Netherlands)
2024
Cornell University
2024
Weill Cornell Medicine
2024
Health Foundation
2024
Université Grenoble Alpes
2008-2024
Purpose: Measured values of ultrasound attenuation in bone represent a combination different loss mechanisms. As wave is transmitted from fluid into bone, reflections occur at the interface. In mode conversion occurs between longitudinal and shear modes mechanical scattered by its complex internal microstructure. Finally, part energy absorbed converted heat. Due to complexity propagation difficulty performing measurements that are capable separating various mechanisms, there currently no...
Abstract Aims Matrix metalloproteinases (MMPs) play a major role in wound healing: they can degrade all components of the extracellular matrix. In diabetic foot ulcers there is an excess MMPs and decrease tissue inhibitors (TIMPs). This imbalance probably one cause impaired healing. However, little known about changes during Methods Sixteen patients with neuropathic participated. Wound fluid was collected regularly 12‐week follow‐up period, for measurement MMP‐1, MMP‐2, MMP‐8, MMP‐9 TIMP‐1....
Several ultrasound-based techniques for the estimation of soft tissue elasticity are currently being investigated. Most them study medium response to dynamic excitations. Such responses usually modeled in a purely elastic using Green's function solution motion equation. However, by itself is not necessarily discriminant parameter malignancy diagnosis. Modeling viscous properties tissues could also be great interest tumor characterization. We report this paper an explicit derivation and...
Nonlinear resonant ultrasound spectroscopy (NRUS) is a resonance-based technique exploiting the significant nonlinear behavior of damaged materials. In NRUS, frequency(ies) an object studied as function excitation level. As level increases, elastic nonlinearity manifest by shift in resonance frequency. This study shows feasibility this for application to damage assessment bone. Two samples bovine cortical bone were subjected progressive induced mechanical cycling. Before cycling commenced,...
A previously healthy 13-year-old boy was hospitalised in April 2020 following 7 days of fever along with abdominal and thoracic pain, odynodysphagia a new skin eruption first seen on the day admission. Besides paracetamol, there were no other current treatments. Our patient's mother
Low-intensity transcranial focused ultrasound (tFUS) has gained considerable attention as a promising noninvasive neuromodulatory technique for human brains. However, the complex morphology of skull hinders scholars from precisely predicting acoustic energy transmitted and region brain impacted during sonication. This is due to fact that different frequencies variations greatly affect wave propagation through skull.Although properties have been studied tFUS applications, such tumor ablation...
Prematurity affects 11% of the births and is main cause infant mortality. On opposite case, failure induction parturition in case delayed spontaneous birth associated with fetal suffering. Both conditions are precocious and/or cervical ripening. Quantitative objective information about temporal evolution ripening may provide a complementary method to identify cases at risk preterm delivery assess likelihood successful labour. In this study, stiffness was measured vivo pregnant sheep by using...
Poly(N-isopropylacrylamide) (pNIPAm) microgels (microgels) are colloidal particles that have been used extensively for biomedical applications. Typically, these synthesized in the presence of an exogenous cross-linker, such as N,N′-methylenebis(acrylamide) (BIS); however, recent studies demonstrated pNIPAm can be absence resulting formation ultralow cross-linked (ULC) particles, which highly deformable. Microgel deformability has linked certain cases to enhanced bioactivity when ULC creation...
In this in silico, vitro, and vivo study, we propose metrics for the characterization of highly scattering media using backscattered acoustic waves MHz range, application to biological media. Multi-element array transducers are used record ultrasonic Inter element Response Matrix (IRM) phantoms lung tissue rodent models pulmonary fibrosis. The distribution singular values IRM frequency domain is then studied quantify multiple contribution. Numerical media, as well gelatin-glass bead...
This work proposes a power law model to describe the attenuation of ultrasonic waves in non-absorbing heterogeneous media with randomly distributed scatterers, mimicking simplified structure cortical bone. paper models propagation structures controlled porosity using two-dimensional finite-difference time domain numerical simulation order measure frequency dependent attenuation. The then fits phenomenological simulated by optimizing parameters under an ordinary least squares framework. Local...