- Botanical Research and Applications
- Potato Plant Research
- Chemical synthesis and alkaloids
- Phytochemistry and biological activities of Ficus species
- Plant tissue culture and regeneration
- Plant Reproductive Biology
- Plant Pathogenic Bacteria Studies
- Plant Molecular Biology Research
- Cassava research and cyanide
- Banana Cultivation and Research
- Biocrusts and Microbial Ecology
- Plant Pathogens and Fungal Diseases
- Plant Pathogens and Resistance
- Light effects on plants
Weizmann Institute of Science
2015-2025
Summary Betalains are tyrosine‐derived red‐violet and yellow pigments, found in plants only of the Caryophyllales order. Although much progress has been made recent years understanding betalain biosynthetic process, many questions remain open with regards to several proposed steps pathway. Most conspicuous by its absence is characterization first committed step pathway, namely 3‐hydroxylation tyrosine form l ‐3,4‐dihydroxyphenylalanine ( ‐ DOPA ). We used transcriptome analysis...
Betalains are tyrosine-derived red-violet and yellow plant pigments known for their antioxidant activity, health-promoting properties, wide use as food colorants dietary supplements. By coexpressing three genes of the recently elucidated betalain biosynthetic pathway, we demonstrate heterologous production these in a variety plants, including major crops: tomato, potato, eggplant, economically important ornamental petunia. Combinatorial expression betalain-related also allowed engineering...
The genus Solanum comprises three food crops (potato, tomato, and eggplant), which are consumed on daily basis worldwide also producers of notorious anti-nutritional steroidal glycoalkaloids (SGAs). Hydroxylated SGAs (i.e. leptinines) serve as precursors for leptines that act defenses against Colorado Potato Beetle (Leptinotarsa decemlineata Say), an important pest potato worldwide. However, SGA hydroxylating enzymes remain unknown. Here, we discover 2-OXOGLUTARATE-DEPENDENT-DIOXYGENASE...
Significance Plants synthesize a vast repertoire of steroidal specialized metabolites. These include the well-known class antinutritional glycoalkaloids (SGAs), which act as defensive chemicals in Solanaceae, and pharmacologically important widespread saponins. Here, we uncover an elusive enzymatic step that acts on unsaturated We find GLYCOALKALOID METABOLISM25 (GAME25) at key branch point biosynthesis pathways The activity GAME25 not only affects enormous diversity SGAs saponins, are...
Betalains are tyrosine-derived red-violet and yellow pigments found in plants only of the Caryophyllales order, which hold both scientific economic values. Their pH in-dependence high stability make them a natural pigment choice for food industries. strong antioxidant activities have prompted research into their potential health-promoting properties led to commercialization variety betalain-based dietary supplements. While biosynthetic process many colorants is well understood, questions...