A5018894998- Polyomavirus and related diseases
- Antenna Design and Analysis
- Full-Duplex Wireless Communications
- Plant Virus Research Studies
- Fungal Infections and Studies
- Streptococcal Infections and Treatments
- Toxin Mechanisms and Immunotoxins
- Antifungal resistance and susceptibility
- Tumors and Oncological Cases
- Diphtheria, Corynebacterium, and Tetanus
- Cancer-related Molecular Pathways
- Carcinogens and Genotoxicity Assessment
- DNA Repair Mechanisms
- Nanoplatforms for cancer theranostics
University of Washington
2007-2014
Emory University
2010-2014
Fred Hutch Cancer Center
2007-2011
QIMR Berghofer Medical Research Institute
2011
Medical University of Graz
2011
Seattle Cancer Care Alliance
2007
Cancer Research Center
2007
Purpose Merkel cell carcinoma (MCC) is a polyomavirus-associated skin cancer that frequently lethal and lacks established prognostic biomarkers. This study sought to identify biomarkers improve accuracy provide insight into MCC biology. Patients Methods Gene expression profiles of 35 tumors were clustered based on prognosis. The cluster genes overexpressed in good-prognosis was tested for biologic process enrichment. Relevant mRNA differences confirmed by quantitative polymerase chain...
BackgroundMerkel cell polyomavirus (MCPyV) has been detected in approximately 75% of patients with the rare skin cancer Merkel carcinoma. We investigated prevalence antibodies against MCPyV general population and association between these
Abstract BACKGROUND: Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy with a high risk of lymph node involvement. To the authors' knowledge, few data have been published to date regarding optimal regional therapy for node‐positive patients. This cohort study was performed analyze outcomes patients MCC treated irradiation as definitive compared completion lymphadenectomy (CLND). METHODS: Fifty involvement at presentation and adequate follow‐up were included in this analysis....
To determine whether there is an association between duration of voriconazole therapy and number nonmelanoma skin cancers (NMSC) after lung transplantation.A telephone-based survey chart review were performed for all living patients who received a transplant at Emory University from 1993 to 2009.Academic medical center.Lung recipients.Number NMSC transplantation.Sixty 91 (65.9%) subjects exposed least 3 months (11.2 ± 8.7 months, range 3-58 months) transplantation, whom 16 developed NMSC,...
Multiple human epidemiologic studies link caffeinated (but not decaffeinated) beverage intake with significant decreases in several types of cancer, including highly prevalent UV-associated skin carcinomas. The mechanism by which caffeine protects against cancer is unknown. Ataxia telangiectasia and Rad3-related (ATR) a replication checkpoint kinase activated DNA stresses one targets caffeine. Suppression ATR, or its downstream target 1 (Chk1), selectively sensitizes DNA-damaged malignant...
The College of American Pathologists offers these protocols to assist pathologists in providing clinically useful and relevant information when reporting results surgical specimen examinations. regards the elements ‘‘Surgical Pathology Cancer Case Summary (Checklist)’’ portion as essential pathology report. However, manner which are reported is at discretion each specific pathologist, taking into account clinician preferences, institutional policies, individual practice. developed an...
The College of American Pathologists offers these protocols to assist pathologists in providing clinically useful and relevant information when reporting results surgical specimen examinations. regards the elements "Surgical Pathology Cancer Case Summary (Checklist)" portion as essential pathology report. However, manner which are reported is at discretion each specific pathologist, taking into account clinician preferences, institutional policies, individual practice.The developed an...