A5051998380- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Spinal Hematomas and Complications
- Spinal Dysraphism and Malformations
- Acute Ischemic Stroke Management
- Glioma Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Bone Tumor Diagnosis and Treatments
- Cerebral Venous Sinus Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury Research
- Advanced MRI Techniques and Applications
- Facial Trauma and Fracture Management
- Fetal and Pediatric Neurological Disorders
- Bone and Joint Diseases
- Sinusitis and nasal conditions
Stony Brook University Hospital
2017-2025
Neurological Surgery
1998-2025
Stony Brook University
2020-2025
Stony Brook School
2025
Stony Brook Medicine
2023-2024
Helsinki University Hospital
2006-2023
Shahid Beheshti University of Medical Sciences
2023
University of Illinois Chicago
2012-2020
University of Illinois Hospital & Health Sciences System
2012
Istanbul University
1997-2010
INTRODUCTION: Long-term follow-up studies in patients with brain arteriovenous malformations (AVMs) have yielded contradictory results regarding both risk factors for rupture and annual rate. We performed a long-term study an unselected, consecutive patient population AVMs admitted between 1942 2005 to the Department of Neurosurgery at Helsinki University Hospital. METHODS: Patients untreated were followed from admission until death, occurrence AVM rupture, initiation treatment, or end 2005....
Long-term follow-up studies in patients with brain arteriovenous malformations (AVM) have been scarce and without proper statistical estimates of mortality. We performed a retrospective survival study 623 consecutive AVMs admitted to the Department Neurosurgery Helsinki University Hospital between 1951 2005.Patients were followed from admission until death or end 2005. Patient was estimated using relative ratio, which provides measure excess mortality experienced by compared general Finnish...
Treatment of Spetzler-Martin Grade IV and V brain arteriovenous malformations (ie, high-grade AVMs) carries a high risk morbidity even mortality. However, little is known about the behavior these lesions if left untreated.To investigate natural history patients with AVMs.Patients untreated AVMs admitted to our center between 1952 2005 were followed from admission until death, AVM rupture, or initiation treatment. Rates rupture various factors analyzed using Kaplan-Meier life table analyses...
OBJECTIVE This study presents the combined experience of two Finnish neurosurgical centers in treatment 501 consecutive patients with distal anterior cerebral artery (DACA) aneurysms. Our aim was to compare outcomes these lesions intracranial aneurysms general and identify factors predicting outcome. METHODS We analyzed clinical radiological data all focused on 427 treated between 1980 2005, era microsurgery computed tomographic imaging. No were lost follow-up. compared outcome ruptured DACA...
To determine whether proton magnetic resonance spectroscopy (MRS), a newer radiographic technology, would be useful in the evaluation of thalamus patients vegetative states resulting from traumatic brain injury.14 victims severe injury who were state and whose images normal underwent bilateral thalamic (MRS) studies. The N-acetyl aspartate to creatine (NAA:Cr) choline (Cho:Cr) ratios obtained for each patient. MRS findings persistent (n = 8) had regained awareness after being 6) compared...
OBJECTIVE Distal anterior cerebral artery (DACA) aneurysms have special anatomic features such as small size, broad base with originating branches, association (ACA) anomalies, and multiple aneurysms. Our aim is to evaluate incidences of these findings from pretreatment angiograms help both microsurgical endovascular treatment planning. METHODS We performed detailed angiographic analysis 101 consecutive patients diagnosed DACA 1998 2007 in the Department Neurosurgery at Helsinki University...
Mitogen-activated protein kinases (MAPKs) are involved in vascular wall remodeling, but their role the pathogenesis of intracranial aneurysms (IAs) is poorly known. We investigated expression and phosphorylation 3 major mitogen-activated kinases, c-Jun N-terminal kinase (JNK), p38, extracellular signal-regulated kinase, unruptured ruptured human IAs.Tissue samples (n=24, 12 IAs) were obtained during microneurosurgical clipping. The localization proteins was studied by immunofluorescent...
Although ethanol intoxication is reported to be a complicating factor in traumatic brain injury, some recent studies are indicating its possible protective role especially at lower doses. Ethanol inhibition of NMDA-mediated excitotoxicity which predominates doses believed responsible for this protection. The aim study was demonstrate neuroprotective alcohol using immunoreactivity synaptophysin as an indirect marker severity injury. Acute moderate performed 2 h prior trauma. Severe injury...
Multiple cerebral cavernous malformations (MCCMs) typically occur in patients with a family history of these lesions. Literature on MCCMs is scarce, and little known about their natural history.Of 264 consecutive cavernomas treated at the Department Neurosurgery, Helsinki University Central Hospital, past 27 years, 33 had MCCMs. Lesions were categorized according to Zabramski classification scale. Follow-up questionnaires sent all patients. Outcome was assessed using Glasgow Scale,...
The current literature suggests hyperglycemia can predict poor outcomes in patients with primary intracerebral hemorrhage (ICH). Chronic is seen pre-existing diabetes (DM); however, acute non-diabetic defined as stress-induced (SIH). This study explored the influence of on ICH both presence and absence DM. Data regarding admission glucose, DM, inpatient mortality, modified Rankin Scale (mRS) scores at discharge were available for 636 admitted to Stony Brook Hospital from January 2011...
INTRODUCTION: Stress-induced hyperglycemia (SIH) independently predicts poor outcomes in patients with primary intracerebral hemorrhage (ICH). However, no studies have directly compared between ICH SIH to those pre-existing diabetes mellitus (DM). This makes it difficult discern whether adverse are related sympathetic dysregulation that occurs as a sequela of or secondary chronic endothelial dysfunction DM. METHODS: We collected data for 814 diagnosis who presented Stony Brook Hospital from...