A5016816079- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Agriculture and Biological Studies
- MicroRNA in disease regulation
- Evolution and Paleontology Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA Research and Splicing
- Identification and Quantification in Food
- Wildlife Ecology and Conservation
- Pleistocene-Era Hominins and Archaeology
- Sperm and Testicular Function
- Ecology and biodiversity studies
- Geology and Paleoclimatology Research
- Gene expression and cancer classification
- Circular RNAs in diseases
- Genomics and Phylogenetic Studies
- Sexual Differentiation and Disorders
Ludwig-Maximilians-Universität München
2023-2024
University of Ljubljana
2015-2023
After the domestication of goats around 10,000 years before present (BP), humans transported far beyond range their wild ancestor, bezoar goat. This brought domestic into contact with many goat species such as ibex and markhor, enabling introgression between goats. To investigate this, while shedding light on taxonomic status goats, we analysed genome-wide SNP data 613 specimens from 14 units, including Capra hircus, C. pyrenaica, (from Switzerland, Austria, Germany Slovenia), aegagrus...
Abstract Background Local breeds retained unique genetic variability important for adaptive potential especially in light of challenges related to climate change. Our first objective was perform, the time, a genome-wide diversity characterization using Illumina GoatSNP50 BeadChip autochthonous Drežnica goat breed from Slovenia, and five one local neighboring Austria Italy, respectively. For optimal conservation breeding programs endangered breeds, it is detect past admixture events strive...
Abstract Background Male infertility is a disorder of the reproductive system with highly complex genetic landscape. In most cases, reason for male remains unknown; however, importance abnormalities in diagnosis subfertility/infertility becoming increasingly recognized. Several syndromes include impaired fertility clinical picture, although comprehensive analysis causes syndromology perspective reproduction not yet available. Objectives (1) To develop catalog and corresponding genes...
Background Breeding of the genetically polled animals is desirable approach in modern cattle husbandry. At least four different genetic variants associated with polledness have been identified, suggesting heterogeneity. These dominant identified on chromosome 1 between regions approx. 2.42 to 2.73 Mb (reference: ARS-UCD1.2), also called POLLED locus. Among these variants, Friesian (PF, 80 kbp duplication) and Celtic (PC, 212 bp complex InDel) are most observed majority breeds production...
Population genomic analyses such as inference of population structure and identifying signatures selection usually involve the application a plethora tools. The installation tools their dependencies, data transformation, or series preprocessing in particular order sometimes makes challenging. While usage container-based technologies has significantly resolved problems associated with requiring multistep pipelines complex transformation can greatly be facilitated by workflow management...
Abstract Background Local breeds retained unique genetic variability important for adaptive potential especially in light of challenges related to climate change. One objective was perform, the first time, a genome-wide diversity characterization using Illumina GoatSNP50 BeadChip autochthonous Drežnica goat breed from Slovenia, five and one local neighboring Austria Italy, respectively. For optimal conservation breeding programs endangered breeds, it is detect past admixture events strive...
MicroRNAs (miRNAs) are small non-coding RNAs that play key roles in regulating gene expression. Polymorphisms miRNA precursors, target genes or within components of silencing machinery contribute significantly to the phenotypic diversity animals. Due this role miRNAs became subject increased research interest association with production traits livestock. In article we presented examples associations between and phenotypes four livestock species: cattle, pig, sheep, chicken. Most studies...
In Europe, the Alpine ibex (Capra ibex) was on brink of extinction in 19th century. Therefore, different conservation measures were implemented, and several reintroductions made arc, starting from only surviving population Gran Paradiso, Italy. An extreme historical bottleneck additional have strongly shaped genetic make-up recent populations, resulting significant drift profound inbreeding across species range. To support science-based actions, molecular methods been increasingly used....
Abstract Understanding miRNA regulatory networks is essential for revealing functions and enables faster biomarker discovery. Protocols building integrated resources of regulomes have been developed in human cattle, but not other species. We screened available genomic an integrative map elements chicken. For the analysis we chose gga-mir-1658, previously reported as having polymorphic mature seed regions, responsible target binding, potential designing strategies control avian influenza...
Genomic analyses in livestock animals, beside the obvious contribution to applications agriculture, provide important insights into biodiversity research and species conservation. The Drežnica goat (Capra hircus) is only Slovenian local breed with critically endangered status. Its robustness adaptability hard Alpine environment are traits worth preserving especially light of climate changes even harsher conditions. aim study was analyse genetic structure its independent origin within other...