A5016830389- Inflammatory Bowel Disease
- IL-33, ST2, and ILC Pathways
- Inflammasome and immune disorders
- Whipple's Disease and Interleukins
- Stoma care and complications
- Oral Health Pathology and Treatment
- Liver Disease and Transplantation
- Colorectal Cancer Surgical Treatments
- Immunotherapy and Immune Responses
- Autoimmune and Inflammatory Disorders
- Microscopic Colitis
- Nutrition and Health in Aging
- Cell Adhesion Molecules Research
Irkutsk Scientific Center of Surgery and Traumatology
2019-2021
Chita State Academy of Medicine
2021
165 patients over 18 years in the period from January 2014 to March 2015 were studied. The aim was investigate prognostic significance of known scale assessment organ dysfunction respect ofpostoperative hepatic failure. development acute liver failure assessed on basis clinical and laboratory data, severity condition by scales MELD, Child-Turcotte-Pugh, Maddrey, Schindl, BILE score, SOFA. paper identified incidence offorms (hepatic encephalopathy, coagulopathy, hepatorenal syndrome, systemic...
This literature review deals with specifics of the natural course inflammatory bowel disease (IBD) in patients from various ethnic groups and -308G/A -238G/A promoter polymorphisms tumor necrosis factor-alpha (TNF-α) gene. The search PubMed, Medline, Еlibrary.ru databases has led to identify total 20 studies, including 2 meta-analyses, on role TNF-α-308G/A gene polymorphism etiology pathophysiology IBD. is associated increased secretion this proinflammatory cytokine, whereas TNF-α-238G/A...
BACKGROUND: The number of people with intestinal stomas in Russia reaches 140 thousand according to the registry stoma patients. For any outcomes on anterior abdominal wall has an extremely negative effect body image and quality life this patient. AIM : Validation cultural adaptation CIS questionnaire Russian Federation. MATERIALS AND METHODS: official translation was performed current WHO EORTC guidelines. study involved 209 patients from 9 centers (3 national 6 regional) different...
The objective of the study was too polymorphism TNFa(rs1800629), IL10(1800871, 1800896) ITGA4(rs1143674, rs1449263), ITGB7(rs11574532) genes in patients with severe ulcerative colitis (UC) Materials and methods. included 70 people UC who lived Irkutsk region, Republic Buryatia Zabaikalsky krai. Patients were divided into two groups: receiving genetically engineered biological therapy (GIBT; n = 22) basic (n=48). control consisted 115 healthy volunteers. genotypes studied by real-time PCR....
Background : Worldwide studies of genetic material, polymorphisms and prognostic gene models for immune-associated disorders have established differences in trans-ethnic population cohorts, which determine phenotypic other characteristics the course these diseases. Ulcerative colitis (UC) is a chronic immune inflammation colon mucosa. More than 100 associated with multiple integrated cross-talks been discovered. Aim To study ITGA4, ITGB7, TNFα, IL10 genes patients ulcerative belonging to...
<h3></h3> Язвенный колит (ЯК) — это хроническое иммуноопосредованное воспалительное заболевание толстой кишки, которое характеризуется высокой инвалидизацией населения трудоспособного возраста. Точных сведений об эпидемиологии ЯК в России нет. <h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Изучить эпидемиологию за последние 5 лет Забайкальском крае по данным регионального регистра пациентов с воспалительными заболеваниями кишечника (ВЗК). <h3>МАТЕРИАЛ И МЕТОДЫ</h3> С 2017 г. на базе поликлинического...
This literature review is devoted to the study of role polymorphic variants anti-inflammatory interleukin-10 gene (Interleukin-10, IL10) in etiology and pathogenesis ulcerative colitis patients various ethnic groups. Aim . To generalize results obtained from electronic databases on characteristics course different groups, taking into account carriage IL10 polymorphisms. Materials methods Twenty-five studies were selected, including four meta-analyzes associative relationships single...