A5065183502- Spectroscopy and Quantum Chemical Studies
- Photoreceptor and optogenetics research
- Molecular Sensors and Ion Detection
- Thin-Film Transistor Technologies
- Conducting polymers and applications
- Organic Electronics and Photovoltaics
- Thermodynamic properties of mixtures
- Advanced biosensing and bioanalysis techniques
- Molecular spectroscopy and chirality
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- Spectroscopy Techniques in Biomedical and Chemical Research
- Ferrocene Chemistry and Applications
- Protein Structure and Dynamics
- Crystallography and molecular interactions
- Phase Equilibria and Thermodynamics
- Ionic liquids properties and applications
- Biofield Effects and Biophysics
- Luminescence and Fluorescent Materials
- Origins and Evolution of Life
National Chemical Laboratory
2016-2022
Academy of Scientific and Innovative Research
2018-2022
University of New Mexico
2020-2021
Indian Institute of Technology Madras
2013
Noncovalent interactions, in particular the hydrogen bonds and nonspecific long-range electrostatic interactions are fundamental to biomolecular functions. A molecular understanding of local environment, consistently for both specific (hydrogen-bonding) (local polarity) is essential a detailed these processes. Vibrational Stark Effect (VSE) has proven be an extremely useful method measure electric field using infrared spectroscopy carbonyl nitrile based probes. The chemical group would ideal...
Deep eutectic solvents (DESs) have gained popularity in recent years as an environmentally benign, inexpensive alternative to organic for diverse applications chemistry and biology. Among them, alcohol-based DESs serve useful media various due their significantly low viscosity compared other DESs. Despite importance media, little is known how solvation dynamics change a function of the hydrocarbon chain length alcohol constituent. In order obtain insights into chain-length dependence...
A set of triazole-based chromogenic and fluorescent chemosensors with amino acid/carbohydrate–fluorophore conjugates have been designed synthesized. The metal cation-sensing properties glycine–anthracene, C24H24O4N4 (3), glycine–pyrene C26H24O4N4 (4), glucose–anthracene, C32H33O10N3 (5) glucose–pyrene, C34H33O10N3 (6) bio-conjugates studied systematically. significant changes in their absorption spectra are accompanied by a strong color change from light yellow to brown for 3 4 colorless...
Triazole-based unsymmetrically 1,1′-disubstituted ferrocene derivatives 4 and 5 have been synthesized using "click chemistry" with sequential functionalization at the cyclopentadienyl rings. The cation complexation properties of these studied electrochemical spectroscopic techniques. exceptional structural features present in ligands are presence one cholesterol moiety, connected to 1-position center through a 1,2,3-triazole ring, fluorescent linked 1′-position such core another...
Molecular structure and function depend on myriad noncovalent interactions. However, the weak transient nature of interactions in solution makes them challenging to study. Information is typically derived from theory indirect structural data. Solvent fluctuations, not revealed by analysis, further complicate study these Using 2D infrared spectroscopy, we show that strong hydrogen bond n → π* interaction coexist interconvert aqueous solution. We found kinetics interconverting becomes faster...
Electrostatic interactions in proteins play a crucial role determining the structure–function relation biomolecules. In recent years, fluorescent probes have been extensively employed to interrogate polarity biological cavities through dielectric constants or semiempirical scales. A choice of multiple spectroscopic methods, not limited by fluorophores, along with molecular level description electrostatics involving solute–solvent interactions, would allow more flexibility pick and choose...
Charge transport and collection in organic solar cells are heavily influenced by traps which ultimately limit the ability to harvest all photogenerated carriers. We investigate photocurrent responses of subjected varying degrees aging from time- frequency-domain perspectives. Intensity-modulated spectroscopy (IMPS) is primarily used here resolve effect trap-assisted nongeminate charge recombination over a broad frequency range (e.g., ∼1 mHz–1 MHz). use combination IMPS time-dependent...
We investigate the degradation phenomena of organic solar cells based on nonfullerene electron acceptors (NFA) using intensity-modulated photocurrent spectroscopy (IMPS). Devices composed NIR absorbing blends a polymer (PTB7) and NFA molecules (COi8DFIC) were operated in air for varying periods time that display unusual trends. Light aging (e.g., ∼3 days) results characteristic first quadrant (positive phase shifts) feature IMPS Nyquist (Bode) plots grow amplitude frequency with increasing...
Barbituric acid is believed to be a proto-RNA nucleobase that was used for biological information transfer on prebiotic earth before DNA and RNA in their present forms evolved. Nucleobases have various tautomeric the relative stability of these critical function. It has been shown barbituric tri-keto form gas phase an enol solid state. However, its dominant aqueous medium most relevant biology investigated only limited extent findings are inconclusive. We multiple approaches, namely,...
In a conventional infrared (IR) spectrum, the peak positions of stretching modes are used for molecular characterization while widths relate to dynamics. With advance ultrafast femtosecond lasers, non-linear IR spectroscopic methods have evolved probe Multiple radiation field-matter interactions allow two dimensional (2D-IR) spectroscopy study structural fluctuations and corformational interchanges in biomolecules. Most importantly, an extra dimension provides direct experimental signatures...