Danica Palacio

ORCID: 0000-0002-2505-377X
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About
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Research Areas
  • Pneumonia and Respiratory Infections
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Antibiotic Use and Resistance
  • Transplantation: Methods and Outcomes
  • Antifungal resistance and susceptibility
  • Esophageal and GI Pathology
  • Genomics and Chromatin Dynamics
  • Nosocomial Infections in ICU
  • Animal Genetics and Reproduction
  • Hippo pathway signaling and YAP/TAZ
  • Bacterial Identification and Susceptibility Testing
  • Vaccine Coverage and Hesitancy
  • RNA Research and Splicing
  • Dysphagia Assessment and Management
  • Axon Guidance and Neuronal Signaling
  • Organ Transplantation Techniques and Outcomes
  • Machine Learning in Healthcare
  • RNA modifications and cancer
  • Polyomavirus and related diseases
  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • Zebrafish Biomedical Research Applications
  • Hernia repair and management
  • Full-Duplex Wireless Communications
  • Hepatitis B Virus Studies

University of Maryland, Baltimore
2021-2025

Trinity Health
2023

University of Maryland Medical Center
2021

Faculdade de Medicina de Jundiaí
2020

Lehigh University
2015

Gram-negative bacteremia (GN-BSI) can cause significant morbidity and mortality, but the benefit of infectious diseases consultation (IDC) is not well defined. A 24-site observational cohort study unique hospitalized patients with 4861 GN-BSI episodes demonstrated a 40% decreased risk 30-day mortality in IDC compared to those without IDC.

10.1093/cid/ciad383 article EN Clinical Infectious Diseases 2023-07-04

Abstract Background Respiratory infections are among the most common reasons antibiotics prescribed. However, 30-50% of patients started on for CAP do not have bacterial infections. Methods We implemented clinical decision support (CDS) in electronic health record two hospitals to diagnosis viral vs. CAP. The CDS (1) estimates probability using logic from a publicly available calculator and (2) provides probability-based options diagnostic testing. is triggered by an order respiratory virus...

10.1093/ofid/ofae631.1772 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Plexins (plxns) are transmembrane (TM) receptors involved in the guidance of vascular, lymphatic vessel, and neuron growth as well cancer metastasis. Plxn signaling results cytosolic GTPase-activating protein activity, previous research implicates dimerization important for activation plxn signaling. Purified, soluble extracellular domains exhibit only weak homomeric interactions, suggesting a role TM juxtamembrane regions homooligomerization. In this study, we consider heptad repeat Danio...

10.1371/journal.pone.0116368 article EN cc-by PLoS ONE 2015-01-07

Outcomes for critically ill people living with human immunodeficiency virus (PLHIV) have changed the use of antiretroviral therapy (ART). To identify these outcomes and correlates mortality in a contemporary cohort an urban academic medical center Baltimore, city high burden HIV, we conducted retrospective study individuals admitted to intensive care unit (MICU) at tertiary between 2009 2014. PLHIV who were least 18 years age index MICU admission ≥24 hours during 5-year period included this...

10.1097/md.0000000000029750 article EN cc-by-nc Medicine 2022-07-15

Abstract Misdiagnosis of bacterial pneumonia increases risk exposure to inappropriate antibiotics and adverse events. We developed a diagnosis calculator ( https://calculator.testingwisely.com ) inform clinical community-acquired using objective indicators, including incidence disease, factors, sensitivity specificity diagnostic tests, that were identified through literature review.

10.1017/ash.2023.408 article EN cc-by-nc-nd Antimicrobial Stewardship & Healthcare Epidemiology 2023-01-01

10.1007/s40506-021-00251-y article EN Current treatment options in infectious diseases/Current treatment options in infectious disease 2021-07-01
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