For biomedical applications, such as targeted drug delivery and microsurgery, it is essential to develop a system of swimmers that can be propelled wirelessly in fluidic environments with good control. Here, we report the construction operation chiral colloidal propellers navigated water micrometer-level precision using homogeneous magnetic fields. The are made via nanostructured surfaces produced large numbers. nanopropellers carry chemicals, push loads, act local probes rheological measurements.

Richard Feynman's 1959 vision of controlling devices at small scales and swallowing the surgeon has inspired science-fiction Fantastic Voyage film played a crucial role in rapid development microrobotics field. Sixty years later, we are currently witnessing dramatic progress this field, with artificial micro- nanoscale robots moving within confined spaces, down to cellular level, performing wide range biomedical applications interior while addressing limitations common passive nanosystems....

Controlled motion of artificial nanomotors in biological environments, such as blood, can lead to fascinating biomedical applications, ranging from targeted drug delivery microsurgery and many more. In spite the various strategies used fabricating actuating nanomotors, practical issues related fuel requirement, corrosion, liquid viscosity have limited model systems water, serum, or biofluids diluted with toxic chemical fuels, hydrogen peroxide. As we demonstrate here, integrating conformal...

This paper presents the shear strength characteristics of a low lime class F fly ash modified with alone or in combination gypsum. Unconfined compression tests were conducted for both unsoaked and soaked specimens cured up to 90 days. Addition small percentage gypsum (0.5 1.0%) along (4–10%) enhanced within short curing periods (7 28 days). The gain unconfined compressive (qu) was 2,853 3,567% at days curing, respectively, addition 10% 1% ash. effect 24h soaking showed reduction qu varying...

Spatiotemporally controlled active manipulation of external micro-/nanoprobes inside living cells can lead to development innovative biomedical technologies and inspire fundamental studies various biophysical phenomena. Examples include gene silencing applications, real-time mechanical mapping the intracellular environment, studying cellular response local stress, many more. Here, for first time, internalization subsequent a system helical nanomotors driven by small rotating magnetic fields...

An important goal in nanotechnology is to control and manipulate submicrometer objects fluidic environments, for which optical traps based on strongly localized electromagnetic fields around plasmonic nanostructures can provide a promising solution. Conventional plasmonics trapping occurs at predefined spots the surface of nanopatterned substrate severely speed-limited by diffusion colloidal into volume. As we demonstrate, these limitations be overcome integrating with magnetically driven...

Micro- and nanomotors are nonliving micro- nanoparticles that rendered motile by supplying energy from external sources, for example, through asymmetric chemical reactions or the application of electric, magnetic, optical, acoustic fields. Their study is interesting two reasons. First, can impact future biomedical practices, where one envisions intelligent multifunctional nanomachines swarming toward a diseased site delivering therapeutics with high accuracy. The second motivation stems...

Manipulation of colloidal objects with light is important in diverse fields. While performance traditional optical tweezers restricted by the diffraction-limit, recent approaches based on plasmonic allow higher trapping efficiency at lower powers but suffer from disadvantage that nanostructures are fixed space, which limits speed and versatility process. As we show here, nanodisks fabricated over dielectric microrods provide a promising approach toward nanomanipulation: these hybrid...

Millions of root canal treatments fail worldwide due to remnant bacteria deep in the dentinal tubules located within dentine tissue human teeth. The complex and narrow geometry renders current techniques relying on passive diffusion antibacterial agents ineffective. Here, potential actively maneuvered nanobots is investigated disinfect tubules, which can be incorporated during a standard procedure. It demonstrated that magnetically driven reach depths not possible with clinical practices....

Herein, an alternating magnetic field-triggered shape memory polymer composite has been 3D printed as a tissue scaffold that can be remotely deployed at physiological temperatures and extended to soft robotics.

We consider the rotational motion of an elongated nanoscale object in a fluid under external torque. The experimentally observed dynamics could be understood from analytical solutions Stokes equation, with explicit formulae derived for dynamical states as function dimensions and parameters defining Under certain conditions, multiple to equations exist, which have been investigated through numerical analysis their stability against small perturbations sensitivity towards initial conditions....

We study the motion of a ferromagnetic helical nanostructure under action rotating magnetic field. A variety dynamical configurations were observed that depended strongly on direction magnetization and geometrical parameters, which also confirmed by theoretical model, based dynamics rigid body Stokes flow. Although at low Reynolds numbers is typically deterministic, certain experimental conditions nanostructures showed surprising bistable behavior, such switched randomly between two...

We report on a wafer scale fabrication method of three-dimensional plasmonic metamaterial with strong chiroptical response in the visible region electromagnetic spectrum. The system was comprised metallic nanoparticles arranged helical fashion, high degree flexibility over choice underlying material, as well their geometrical parameters. This resulted exquisite control properties, most importantly spectral signature circular dichroism. In spite large variability arrangement, size and shape...

Abstract A wide variety of applications are envisioned and demonstrated with artificial micro‐ nanomachines, ranging from targeted drug or gene delivery, microsurgery, environmental sensing, many more. Here, it is how helical nanomachines can be used to measure map the local mechanical properties a complex heterogeneous environment. The positions precisely controlled using externally applied magnetic fields, while their instantaneous orientations provide estimation viscosity surrounding...

There is considerable interest in powering and maneuvering nanostructures remotely fluidic media using noninvasive fuel-free methods, for which small homogeneous magnetic fields are ideally suited. Current strategies include helical propulsion of chiral nanostructures, cilia-like motion flexible filaments, surface assisted translation asymmetric colloidal doublets nanorods, all the individual structures moved a particular direction that completely tied to characteristics driving fields. As...

This paper presents the results of a laboratory investigation on tensile strength, bearing ratio, and slake durability characteristics class F fly ash stabilized with lime alone or in combination gypsum. The effects content (4, 6, 10%), gypsum (0.5 1.0%), curing period (up to 90days) are highlighted. Unconfined compressive strength test for mixes cured up 90days presented develop relationships between different strengths (Brazilian flexural) unconfined strength. Both soaked unsoaked ratio...

A light beam changes direction as it enters a liquid at an angle from another medium, such air. Should the contain molecules that lack mirror symmetry, then has been predicted by Fresnel will not only change direction, but actually split into two separate beams with small difference in respective angles of refraction. Here we report observation this phenomenon. We also demonstrate reflection does equal incidence chiral medium. Unlike conventional optical rotation, which depends on...

Recycling of waste material is one the effective solutions its disposal problem. Fly ash produced by coal-based thermal power plants and phosphogypsum (PG) fertilizer producing phosphoric acid as constituent fertilizers, take huge area creates environmental problems. Stabilization/solidification fly improves engineering properties reduces problem like leaching dusting. This paper presents laboratory test results a Class F pond alone stabilized with varying percentages lime (4, 6, 10%) PG...

This paper presents the study on compaction characteristics of pond ash. Three different types ash have been used in this study. The effects controlling parameters, viz. energy, moisture content, layer thickness, mold area, tank size, and specific gravity dry density are highlighted herein. maximum optimum content vary within range 8.40–12.25kN∕m3 29–46%, respectively. In present investigation, degree saturation at has found to 63–89%. An empirical model developed estimate ash, using...

Combining oblique angle deposition with standard graphene transfer protocols, two planar arrays of metal nanoparticles are fabricated that vertically separated by atomic dimensions, corresponding precisely to the thickness a single layer graphene, i.e., 0.34 nm. Upon illumination light at an appropriate wavelength, local electromagnetic field junction dimers can be increased dramatically, thereby resulting in most sensitive graphene–plasmonic hybrid photodetector reported date.

Helical propulsion is at the heart of locomotion strategies utilized by various natural and artificial swimmers. We used experimental observations a numerical model to study fluctuation mechanisms that determine performance an externally driven helical propeller as size helix reduced. From causality analysis, overwhelming effect orientational noise low length scales observed, which strongly affects average velocity direction motion propeller. For smaller than few micrometers in aqueous...

Magnetic nanomotors with integrated theranostic capabilities can revolutionize biomedicine of the future. Typically, these contain ferromagnetic materials, such that small magnetic fields be used to maneuver and localize them in fluidic or gel-like environments. Motors large permanent moments tend agglomerate, which limits scalability this otherwise promising technology. Here, we demonstrate application a microwave-synthesized ferrite layer reduce agglomeration helical by an order magnitude,...

The invasion of cancer is brought about by continuous interaction malignant cells with their surrounding tissue microenvironment. Investigating the remodeling local extracellular matrix (ECM) invading can thus provide fundamental insights into dynamics progression. In this paper, we use an active untethered nanomechanical tool, realized as magnetically driven nanomotors, to locally probe a 3D culture environment. We observed that nanomotors preferentially adhere cancer-proximal ECM and...