Yusuke Ichikawa

ORCID: 0000-0002-2526-4681
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About
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Research Areas
  • Hydrogen's biological and therapeutic effects
  • Biochemical effects in animals
  • Anesthesia and Neurotoxicity Research
  • Medical and Biological Ozone Research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Inflammasome and immune disorders
  • Nitric Oxide and Endothelin Effects
  • Hemoglobin structure and function
  • Photosynthetic Processes and Mechanisms
  • Amino Acid Enzymes and Metabolism
  • Chemical Reactions and Isotopes
  • Systemic Lupus Erythematosus Research
  • Usability and User Interface Design
  • Aviation Industry Analysis and Trends
  • Systemic Sclerosis and Related Diseases
  • Respiratory viral infections research
  • Viral Infections and Immunology Research
  • Extracellular vesicles in disease
  • Dietary Effects on Health
  • Hydrogen Storage and Materials
  • Nanomaterials and Printing Technologies
  • Neuroscience of respiration and sleep
  • nanoparticles nucleation surface interactions
  • Restraint-Related Deaths
  • Plasma Applications and Diagnostics

Niigata University
2024-2025

Musashino University
2023

Keio University
1995-2023

Kobe University
2021

NTT (Japan)
2016

Kyoto University
2010-2012

Kyoto Katsura Hospital
2012

National Institute of Infectious Diseases
2011

Tokyo University of Science
2011

Tokyo University of Agriculture
2009

Cluster arrays composed of metal nanoparticles are promising for application in sensing devices because their interesting surface plasmon characteristics. Herein, we report the spontaneous formation cluster gold colloids on flat substrates by vertical-deposition convective self-assembly. In this technique, under controlled temperature, a hydrophilic substrate is vertically immersed colloid suspension. form when particle concentration extremely low (in order 10(-6)-10(-8) v/v). These arranged...

10.1021/la302811y article EN Langmuir 2012-08-23

Hydrogen (H2) is promising as an energy source for the next generation. Medical applications using H2 gas can be also considered a clean and economical technology. Since based on electrolysis of water production has potential to expand medical applications, technology been developed in order safely dilute it supply living body by inhalation, respectively. inert molecule which scavenge highly active oxidants including hydroxyl radical (·OH) peroxynitrite (ONOO−), convert them into water....

10.3390/cleantechnol2040033 article EN cc-by Clean Technologies 2020-12-16

Background: This study aimed to assess the antibody response SARS-CoV-2 vaccines among healthcare workers (HCWs) from multiple outpatient clinics in Japan, examining effects of baseline characteristics (e.g., sex, age, underlying condition, smoking history, occupation) and prior infections. Methods: A total 101 HCWs provided serum at four time points between October 2020 July 2023. received two six doses mRNA vaccine (BNT162b2 or mRNA-1273). Anti-nucleocapsid (N) anti-spike (S) IgG...

10.3390/vaccines13010090 article EN cc-by Vaccines 2025-01-18

Two kinds of basic dendritic (or starburst) all-para-phenylene-linked oligotriarylamines, which are generated from para-phenylenediamine and triphenylamine as core units, respectively, were prepared, the electrochemical, spectroelectrochemical, ESR spectroscopic measurements carried out with respect to their application hole transport materials in optoelectronic devices such organic light-emitting devices. The prepared oligoarylamines exhibits multiredox-active properirs, stably oxidizable...

10.1021/cm102163w article EN Chemistry of Materials 2010-12-21

ABSTRACT To evaluate Ni dynamics at the subcellular level, distribution and speciation of were determined in wild‐type (WT) Ni‐tolerant (NIT) tobacco BY‐2 cell lines. When exposed to low but toxic levels Ni, NIT cells found contain 2.5‐fold more (14% whole‐cell values) their walls than WT (6% values). In addition higher apoplast, a proportion (94%) symplastic was localized vacuoles (81%). The concentration cytosolic significantly lower (18 nmol g −1 FW) that (85 FW). silico simulation showed...

10.1111/j.1365-3040.2009.02068.x article EN Plant Cell & Environment 2009-11-11

Baloxavir marboxil (baloxavir), approved as an anti-influenza drug in Japan March 2018, can induce reduced therapeutic effectiveness due to PA protein substitutions. We assessed substitutions clinical samples from influenza-infected children and adults pre- post-baloxavir treatment, examining their impact on fever symptom duration. During the 2022-2023 influenza season, predominant circulating subtype detected by cycling-probe RT-PCR was A(H3N2) (n = 234), with a minor circulation of...

10.1016/j.antiviral.2024.105956 article EN cc-by Antiviral Research 2024-07-04

Despite the fact that we have reported on dangers of explosion hydrogen gas inhalers, inhalers with explosive hazards are, as a matter fact, still being sold today. In this study, investigated past reports inhaler accidents to clarify causes these incidents. As result investigation, found central cause was leakage inside inhaler. Although it is said concentration between 10% and 75%, does not explode above 75% due lack oxygen, confirmed through series ignition experiments explosions can...

10.4103/2045-9912.344972 article EN Medical Gas Research 2022-07-18

Peroxide-bound heme species have been considered difficult to detect under physiological conditions because of their intrinsically transient properties. Cytochrome c552 (cyt c552), from Thermus thermophirus HB8, bearing a mutation an alanine at Met69 (M69A) reacts with hydrogen peroxide (H(2)O(2)) generate detectable hydroperoxo-ferric ([Fe(3+)--OOH]) ambient temperature. EPR measurements during appropriate reaction periods reveal that the [Fe(3+)--OOH] is in preequilibrium state between...

10.1002/cbic.200600135 article EN ChemBioChem 2006-08-21

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained and malaise that persist for more than 6 months with neuropsychiatric symptoms, including slight fever, headache, weakness, impaired thinking, depression.[1,2] The onset severity of these symptoms vary reduce the quality life as well social, occupational, personal activities those affected, some becoming bedridden.[1,2] number ME/CFS patients in United States estimated to be between 836,000 2.5...

10.4103/2045-9912.385441 article EN Medical Gas Research 2023-09-08

Changes in heme coordination state and protein conformation of cytochrome P450cam (P450cam), a b-type protein, were investigated by employing pH jump experiments coupled with time-resolved optical absorption, fluorescence, circular dichroism, resonance Raman techniques. We found partially unfolded form (acid form) ferric at 2.5, which Cys–-heme bond the native was ruptured. When raised to 7.5, acid refolded through distinctive intermediate. Formations similar intermediate forms also observed...

10.1074/jbc.m310810200 article EN cc-by Journal of Biological Chemistry 2004-07-01
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