- Ginseng Biological Effects and Applications
- Genomics and Phylogenetic Studies
- Pharmacological Effects of Natural Compounds
- Natural product bioactivities and synthesis
- Cancer Risks and Factors
- Microbial Community Ecology and Physiology
- Global Cancer Incidence and Screening
- Plant Pathogens and Fungal Diseases
- Health and Wellbeing Research
- Food Quality and Safety Studies
- Plant Disease Resistance and Genetics
- Nutrition, Health and Food Behavior
- Bacteriophages and microbial interactions
- Plant-Microbe Interactions and Immunity
- Colorectal Cancer Screening and Detection
- Probiotics and Fermented Foods
- Plant Pathogenic Bacteria Studies
- Helicobacter pylori-related gastroenterology studies
- Plant tissue culture and regeneration
- Fungal Biology and Applications
- Agriculture, Soil, Plant Science
- Cervical Cancer and HPV Research
- Glioma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Viral Infectious Diseases and Gene Expression in Insects
Kyung Hee University
2016-2025
Seoul National University Bundang Hospital
2009-2025
Hallym University
2025
National Institutes of Health
2024
Seoul Women's University
2024
Yonsei University
2008-2024
Wayne State University
2024
Seoul Veterans Hospital
2024
Maria Fertility Hospital
2024
Korea Disease Control and Prevention Agency
2010-2023
Circulating, cell-free microRNAs (miRNAs) are promising candidate biomarkers, but optimal conditions for processing blood specimens miRNA measurement remain to be established. Our previous work showed that the majority of plasma miRNAs likely cell-derived. In course profiling lung cancer cases versus healthy controls, we observed a broad increase in circulating levels compared controls and higher expression correlated with platelet particle counts. We therefore hypothesized quantity residual...
Background It has been proposed that time spent sitting increases all-cause mortality, but evidence to support this hypothesis, especially the relative effects of various activities alone or in combination, is very limited. Methods The association between sedentary behaviours (time spent: watching television (TV); other leisure activities; a car/bus; at work; and meals) mortality (all-cause cause-specific) was examined Multiethnic Cohort Study, which included 61 395 men 73 201 women aged...
Abstract Obesity has been associated with an increased risk of postmenopausal breast cancer. Adipokines and systemic inflammation have hypothesized to underlie this association. In a case–control study nested within the Multiethnic Cohort, conditional logistic regression was used calculate ORs 95% confidence intervals (CI) for cancer prediagnostic levels serum leptin, adiponectin, leptin:adiponectin ratio, C-reactive protein (CRP). The 706 cases controls were matched on ethnicity, location...
Dendropanax morbifera Léveille is an oriental medicinal plant that traditionally used in folk medicine and grows a specific region of South Korea. We aimed to enhance the utilization D. plants for synthesis silver nanoparticles (AgNPs) gold (AuNPs). leaf extract acted as both reducing stabilizing agent rapidly synthesized AgNPs (D-AgNPs) AuNPs (D-AuNPs). The D-AgNPs D-AuNPs were characterized by ultraviolet-visible spectroscopy, energy dispersive X-ray analysis, elemental mapping, field...
Abstract: There has been a growing interest in the design of environmentally affable and biocompatible nanoparticles among scientists to find novel safe biomaterials. Panax ginseng Meyer berries have unique phytochemical profile exhibit beneficial pharmacological activities such as antihyperglycemic, antiobesity, antiaging, antioxidant properties. A comprehensive study biologically active compounds berry extract (GBE) ability (GB) material for biosynthesis gold (GBAuNPs) silver (GBAgNPs) was...
"Healthy Twin" is a twin family study extension of the existing Korean Twin-Family Register. Healthy Twin recruits adult like-sex twins over age 30 and their members. protocols are primarily tailored to quantitative trait loci complex traits as well role environment in etiology diseases. A full-length survey underway, including questionnaires, health examinations collection biological specimens. So far, 820 individuals (169 pairs families) have participated 1068 individual (608 pairs)...
Although the incidence of breast cancer in Asia remains lower than North America, Western Europe, and Oceania, rates have been increasing rapidly during past few decades, Asian countries now account for 40% cases diagnosed worldwide. Breast mortality has also increased among women, contrast to decreased Northern Oceania. These are associated with higher prevalence risk factors (e.g., reduced parity, delayed childbirth, obesity) that accompanied economic development throughout region....
Abstract Background: The role of soybean products in gastric cancer risk is not clear epidemiologic studies due to measurement error from dietary intake questionnaires and different degrees bias according study design. To examine the association between risk, we measured phytoestrogen biological markers a nested case-control study. Methods: population was composed 131 cases 393 matched controls within Korean Multicenter Cancer Cohort. concentrations four biomarkers plasma samples were using...
Bioactive compounds in plant extracts are able to reduce metal ions nanoparticles through the process of green synthesis. Panax ginseng is an oriental medicinal herb and adaptogen which has been historically used cure various diseases. In addition, P. leaves-mediated gold value-added novel materials. Its potential as a cosmetic ingredient still unexplored. The aim this study was evaluate antioxidant, moisture retention whitening properties (PgAuNPs) applications.Cell-free experiments were...
Panax ginseng (C.A. Mayer) is a well-known medicinal plant used in traditional medicine Korea that experiences serious salinity stress related to weather changes or incorrect fertilizer application. In ginseng, the use of Paenibacillus yonginensis DCY84T improve salt tolerance has not been thoroughly explored. Therefore, we studied role P. under short-term and long-term conditions controlled environment. vitro testing revealed high indole acetic acid (IAA) production, siderophore formation,...
Background. Previous studies have implicated the relationship between environmental phthalate exposure and attention deficit hyperactivity disorder (ADHD) symptoms of childhood, but no been conducted in children who a confirmed diagnosis ADHD obtained through meticulous diagnostic testing. We aimed to determine whether metabolites urine would be higher with than those without correlate symptom severity cortical thickness children. Method. A cross-sectional examination metabolite...
Background and Purpose— Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in elderly. We undertook an international survey to characterize frequency AF-associated stroke, methods AF detection, patient features. Methods— Consecutive patients hospitalized for 2013 2014 were surveyed from 19 research centers different countries. Data analyzed by global regions World Bank income levels. Results— Of 2144 with 590 (28%; 95%...
Abstract Colorectal cancer (CRC) has a 5-year survival rate of <10%, as it can metastasize to the lungs and liver. Anticancer drugs targeted therapies used treat metastatic colorectal have insufficient therapeutic efficacy are associated with complications. Therefore, research develop new therapeutics is necessary. Here, we present novel discovery that intracellular adhesion molecule-1 (ICAM-1) potential target enhance effectiveness for CRC. ICAM-1 an important regulator cell–cell...