- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Healthcare Systems and Public Health
- Intramuscular injections and effects
- Diabetes and associated disorders
- Salivary Gland Disorders and Functions
- Protein Tyrosine Phosphatases
Krasnoyarsk Regional Clinical Hospital
2022-2024
Background. Currently, observations are accumulating indicating the negative effect of therapy with a number biologic disease-modifying anti-rheumatic drugs (bDMARDs) on course COVID-19. These facts determine relevance studying factors severe and unfavorable outcome in immuno-inflammatory rheumatic diseases (IIRD) patients treated bDMARDs order to develop tactics for managing this category pandemic. Aim. To evaluate influence clinical demographic risk development, severity outcomes new...
Sjogren's disease is an immunoinflammatory rheumatic that characterized by damage to the secreting epithelial glands with development of parenchymal sialadenitis xerostomia and keratoconjunctivitis sicca hypolacrymia. Due high heterogeneity clinical manifestations this disease, diagnosis difficult. This article presents a case patient detailed description manifestation, course, treatment rare combination extraglandular complications in form polymyositis secondary polyneuropathy.
A retrospective analysis of the database register patients with immuno-inflammatory rheumatic diseases receiving treatment biologic disease-modifying anti-rheumatic drugs in Novosibirsk region was carried out, which included 318 patients, 94 whom had indications pneumonia during period from 01.04.2020 to 31.12.2020. There a statistically significant increase risk developing over age 60 years and rituximab, while therapy TNF-α inhibitors significantly reduced pneumonia. Keywords: COVID-19,...