A human exhaled air analysis by means of infrared (IR) laser photoacoustic spectroscopy is presented. Eleven healthy nonsmoking volunteers (control group) and seven patients with chronic obstructive pulmonary disease (COPD, target were involved in the study. The principal component method was used to select most informative ranges absorption spectra patients' terms separation studied groups. It shown that data profiles spectrum allow identifying COPD comparison control group.

It is important to identify patients with chronic obstructive pulmonary disease (COPD) and lung cancer in the early stages of disease. The method laser opto-acoustic gas analysis, this case, can act as a promising tool for diagnostics. material study were emission samples collected from healthy volunteers – exhaled air, swabs teeth cheeks. A set was formed three groups: volunteers, COPD, patients. resulting analyzed by means analyzers: intracavity location detector (ILPA-1), extracavity...

Technique of exhaled breath sampling is discussed. The procedure wavelength auto-calibration proposed and tested. Comparison the experimental data with model absorption spectra 5% CO2 conducted. classification results three study groups obtained by using support vector machine principal component analysis methods are presented.

The aim of the study was to identify general patterns and features changes in content hypoxia-inducible factors-1 -2 association with an imbalance cytokines (IL-10, IL-13, galectin-2 -9, IFN-gamma) blood diseases associated hypoxia. Materials methods. We examined 25 patients coronary heart disease (CHD) failure II-III according NYHA, 16 chronic obstructive pulmonary (COPD) without exacerbation, infiltrative tuberculosis (TB) before anti-TB therapy, 18 relatively healthy donors. Plasma...

The results of measuring biomarkers in breath air patients with broncho-pulmonary diseases using wide-band frequency tuning IR laser photo-acoustic spectroscopy and the methods data mining are presented. We will discuss experimental equipment various intellectual analysis spectra context above task. work was carried out partial financial support FCPIR contract No 14.578.21.0082 (ID RFMEFI57814X0082).

The authors discuss results of investigations into the structure and functional status erythrocyte membranes in patients with metabolic syndrome. It is shown that pathological process involves not only well known changes serum lipid metabolism but also highly specialized cells, such as erythrocytes. Specifically, erythrocytes undergo marked disorganization membranous phase conjunction a relative increase cholesterol fraction decrease phospholipids levels. Analysis fractional composition...

The aim of the study was to reveal peculiarities vessels microvasculature within lamina propria bronchial mucosa in smokers with and without chronic obstructive pulmonary disease on basis light-optical ultrastructural analysis bronchobiopses. Material Methods. A morphological smoking patients it, an emphasis morphometric performed. one-stage 115 aged 40 60 years (58.3±3.24 years) made (men predominated — 90.9%). Results. In group disease, contrast comparison group, signs vascular remodeling...

The aim of the work is to establish general regularities and features differentiation blood monocytes into 4 subpopulations in diseases associated with circulatory respiratory hypoxia. Materials methods. 18 patients ischemic heart disease (IHD), 12 cardiomyopathy (ICMP), 14 chronic obstructive pulmonary (COPD), 15 newly diagnosed infiltrative tuberculosis (PTB) healthy donors were examined. In whole blood, we determined relative number different by flow cytometry. results analyzed...

The aim of this study was to investigate a role the exhaled air analysis as simple and non-invasive diagnostic method for chronic obstructive pulmonary disease (COPD). Methods. EBC samples were analyzed in 26 patients with acute exacerbation COPD 19 healthy volunteers using photoacoustic gas analyzer ILPA-1 based on CO 2 laser spectral analysis. data obtained used integral estimation (IE) within two ranges. Results. IEs subjects differed significantly not related gender. IE values both...

The results of the joint use laser photoacoustic spectroscopy and chemometrics methods in gas analysis exhaled air patients with respiratory diseases (chronic obstructive pulmonary disease, pneumonia lung cancer) are presented. absorption spectra breath all volunteers were measured, classification scans applied, sensitivity/specificity determined. It obtained a result nosological pairs for investigated volunteers, indices sensitivity specificity.

Pulmonary diseases diagnostics always occupies one of the key positions in medicine practices. A large variety high technology methods are used today, but none them cannot be for early screening pulmonary diseases. We discuss abilities IR and terahertz laser spectroscopy noninvasive express on a base analysis absorption spectra patient's gas emission, particular, exhaled air. Experience field approaches to experimental data hard-ware realization analyzers medical applications is also discussed.

To investigate the impact of smoking on air exhaled by patients with chronic obstructive pulmonary disease (COPD) and asthmatics, applying photoacoustic spectroscopy.The absorption spectra (EAAS) were analyzed in healthy volunteers COPD an ILPA-1 CO2 laser gas analyzer. The procedure based calculation integrated estimate (IE) state object was used to assess findings.Comparison IE EAAS non-smoking individuals showed that compounds, formation which associated smoking, recorded range...

Modern scientific and practical information on urgency, prevalence, etiopathogenesis, clinical implications, laboratory diagnostics, treatment of metabolic syndrome is presented. The paper presents up-to-date for general practice doctors specialized services in order to improve efficiency the discussed category patients.

The results of application the joint use laser photoacoustic spectroscopy and chemometrics methods in gas analysis exhaled air patients with chronic respiratory diseases (chronic obstructive pulmonary disease lung cancer) are presented. absorption spectra breath representatives target groups healthy volunteers were measured; selection by most informative coefficients scan terms separation investigated nosology was implemented.

Bronchopulmonary system diseases are on the first place among causes of people's death. Most methods for lung diagnosis invasive or not suitable children and patients with severe disease. One promising clinical disease activity monitoring bronchopulmonary is analyzing human breath. Directly exhaled breath condensate using breaths analyzing. Analysis can apply diagnostic, long evaluation efficacy treatment diseases. Differential diagnostic between chronic obstructive (COPD) bronchial asthma...

Background. Nowadays little data related to the hemostatic system and fibrinolysis in patients with chronic obstructive pulmonary disease (COPD) are available. This is due lack of standardized methods for studying hemostasis system, as well a single functional test that allows evaluation complete fibrinogenesis cycle whole blood. Aim. The aim our study was develop capable analyzing blood gas composition “point-of-care test” method potential COPD, based on stimulus, which tissue hypoxia....

One of the main non-respiratory functions lungs is participating in regulation hemostasis. Development and progression COPD affects on coagulation anticoagulation systems, leads to thrombosis. The aim our research evaluation hemostatic potential patients with comparison healthy volunteers. involved 10 smoking non-smoking Evaluation hemostasis system was carried out using low-frequency piezoelectric thromboelastography (LPTEG), before one cigarette after. This method allows us perform...

Smoking plays an important role in etiopathogenesis of chronic obstructive pulmonary disease (COPD). Concentration inhaled tobacco highly depends on temperature nicotine warming, so three types consumption can be defined: burning (usual cigarette), solution (electronic warming nicottin (IQOS). The purpose this study was to assess the effect and its decay products state hemostasis system. included 24 volunteers: 8 people smoked usual sigarette, electronic cigarette healthy volunteers IQOS...