A5086635293- Endometriosis Research and Treatment
- Pregnancy and Medication Impact
- Reproductive Biology and Fertility
- Renal and related cancers
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
University of Liverpool
2023
Universitas Gadjah Mada
2020
Peritoneal endometriosis causes pelvic pain and infertility, but the underlying mechanisms related to these symptoms are not fully understood. Endometriosis diagnosis is typically delayed; thus, patient samples unsuitable study early formation in situ. This aimed generate a 3D co-culture model of peritoneal using patient-derived primary cells, providing unique opportunities examine endometriotic lesion initiation progression. wash fluid, fallopian tube mesentery endometrial biopsies were...
Background and Aims: Previous studies have explored the role of neurotrophins their receptors, especially in forming deep endometriosis, endometriosis tissue invasion, its effects on proliferation. However, these do not include research pathogenesis endometriomas. We tried to model invasion endometrioma find out more about by using chorioallantoic membrane (CAM) as host. Immunohistochemistry (IHC) detect neurotrophin BDNF namely TrkB P75, are employed linked between expression process...
Link of Video Abstact: https://youtu.be/noF1KQ1W7Sk Background: The tropomyosin kinase receptor B (TrkB) and p75 receptors may play a role in the formation deep endometriosis are related to more intense pain nodular endometriosis. Neurotrophins brain-derived neurotrophic factor (BDNF) regulate survival, growth, programmed cell death neurons. This study aimed explore expression BDNF its endometrioma tissue invasion implanted chorioallantoic membrane (CAM) chicken eggs. Methods: Peritoneal...
Abstract Background Ovarian tissue vitrification is an alternative fertility preservation procedure for young female patients prior to gonadotoxic treatment. Primordial follicle loss might be a potential issue and transplantation procedures. This study aimed evaluate primordial density deoxyribonucleic acid (DNA) fragmentation in each stage of the goat ovarian tissue. Follicle DNA were examined microscopically after staining with hematoxylin eosin TUNEL assay, respectively. Both parameters...