A5015648392- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Nanoparticles: synthesis and applications
- Characterization and Applications of Magnetic Nanoparticles
- Iron oxide chemistry and applications
- Antimicrobial agents and applications
- Advanced Photocatalysis Techniques
- Photoacoustic and Ultrasonic Imaging
- Graphene and Nanomaterials Applications
- Microfluidic and Bio-sensing Technologies
- Electrochemical sensors and biosensors
- Magneto-Optical Properties and Applications
- Magnetic Properties and Applications
- Magnetic Properties and Synthesis of Ferrites
- Lanthanide and Transition Metal Complexes
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Dendrimers and Hyperbranched Polymers
- Protein purification and stability
- Magnetism in coordination complexes
- Selenium in Biological Systems
- Hydrogen's biological and therapeutic effects
- Genetics, Aging, and Longevity in Model Organisms
- Nanocluster Synthesis and Applications
Jinan University
2017-2025
First Affiliated Hospital of Jinan University
2025
University of Electronic Science and Technology of China
2022-2023
Carrier (United States)
2019-2021
Anhui University
2012-2020
Hefei University
2020
Institut de Ciència de Materials de Barcelona
2014-2017
Consejo Superior de Investigaciones Científicas
2015-2017
Centre de Recerca Matemàtica
2015
Unidades Centrales Científico-Técnicas
2015
Abstract Nowadays, antibiotic abuse increases the emergence of multidrug‐resistant bacterial strains, which is major reason for failure conventional therapies. Therefore, developing novel antibacterial materials or therapies an urgent demand. In present study, photothermal and NO‐releasing properties are integrated into a single nanocomposite to realize more efficient bactericidal effects. To this end, polydopamine (PDA) coated iron oxide (Fe 3 O 4 @PDA) used as photoconversion agent core,...
Abstract For decades, hydrogen (H 2 ) gas has been recognized as an excellent antioxidant molecule that holds promise in treating many diseases like Alzheimer's, stroke, cancer, and so on. the first time, active is demonstrated to be highly efficient antibacterial, antibiofilm, wound‐healing applications, particular when used combination with photothermal effect. As a proof of concept, biocompatible hydrogen‐releasing PdH nanohydride, displaying on‐demand controlled release property under...
An experimental investigation has been made of the dependence coercive force on density some magnetite and gamma ferric oxide powders consisting different sized shaped particles. Various aspects data are discussed. In particular, an interpretation based a calculation critical single domain size iron particles with prolate spheroidal shape is consistent results.
Post-synthesis modification (PSM) is an efficient means to introduce functional chemical groups into metal–organic frameworks (MOFs) by modifying metal clusters or ligands after MOFs have been synthesized.
The variety of nanoparticles (NPs) used in biological applications is increasing and the study their interaction with media becoming more important. Proteins are commonly first biomolecules that NPs encounter when they interact systems either vitro or vivo. Among NPs, super-paramagnetic iron oxide (SPIONs) show great promise for medicine. In this work, we detail formation, composition, structure a monolayer bovine serum albumin (BSA) on SPIONs. We determine, both by molecular simulations...
A novel quartz-fiber torsion balance is employed to make magnetic measurements on individual microscopic ferrite particles. very direct experimental test provides strong evidence for the existence of single-domain Further, results confirm theoretical calculations critical size within a small factor.
Photodynamic therapy (PDT) has attracted extensive attention in the clinical treatment of malignant tumor. However, acidic and hypoxic conditions tumor microenvironment (TME) limit further application PDT clinic. Herein, we fabricate a new nanoplatform─HPDA@MnO2@Ce6/DOX@PEG-RGD (HPMRCD)─by means coating hollow polydopamine nanoparticles (HPDA) with manganese dioxide (MnO2), which is modified by cyclic RGD functionalized poly(ethylene glycol) (PEG) co-loaded photosensitizer, Chlorin e6 (Ce6),...
Currently, treatment of chronically infected wounds still remains a big challenge; thus, novel strategy with highly efficient therapeutic effect is urgent demand. In the present work, we demonstrated that combinational use nitric oxide (NO) and deferoxamine (DFO) promising way for treating hard-to-heal wounds. As proof concept, DFO was first loaded in mesoporous polydopamine (mPDA) then functionalized by chitosan-graft-third generation poly(amidoamine) polymer terminal S-nitrosothiol groups...
Nanomaterials give rise to unique biological reactivity that needs be thoroughly investigated. The quest for enhanced magnetic nanomaterials of different shapes, properties, or surface coatings continues applications in drug delivery, targeting therapies, biosensing, and separation. In this context, the use simple vivo models, such as Caenorhabditis elegans, biologically evaluate nanoparticles is currently increasing demand it offers low-cost information-rich experiments. work, we evaluated...
A multifunctional nanogenerator with NIR II-precise-control NO and alkyl radical release property is elaborately fabricated, which displays a synergistic anticancer effect by significantly inhibiting breast tumor.
Hierarchical, ultrathin, and porous NiMoO4@CoMoO4 on Co3O4 hollow bones were successfully designed synthesized by a hydrothermal route from the Co-precursor, followed KOH (potassium hydroxide) activation process. The hydrothermally nanowires act as scaffold for anchoring units but also show more compatibility with NiMoO4, leading to high conductivity in heterojunction. intriguing morphological features endow hierarchical Co3O4@NiMoO4@CoMoO4 better electrochemical performance where capacity...
Cigarette smoking is the main cause of chronic obstructive pulmonary disease and lung cancer. The present study was aimed to explore chemopreventive effect ursolic acid (UA) on these diseases. In CSE treated normal human bronchial epithelial cell model, UA alleviated cytotoxicity caused by CSE, recovered intracellular redox balance, relieved stimulation external deleterious factors as well. mitigated CSE-induced DNA damage through Nrf2 (nuclear factor erythroid 2-related 2) pathway....
We present a mechanistic study of the effect iron oxide nanoparticles (SPIONs) in Caenorhabditis elegans combining genome-wide analysis with investigation specific molecular markers frequently linked to nanotoxicity. The effects two different coatings were explored: citrate, an anionic stabilizer, and bovine serum albumin, as pre-formed protein corona. transcriptomic identified differentially expressed genes following exposure SPIONs. expression involved oxidative stress, metal...
Simple approaches to synthesize hybrid nanoparticles with magnetic and plasmonic functionalities, high control of their shape avoiding cytotoxic reactants, target biomedical applications remain a huge challenge. Here, we report facile, fast bio-friendly microwave-assisted polyol route for the synthesis complex multi-material consisting monodisperse gold nanotriangles around 280 nm in size uniformly decorated by superparamagnetic iron oxide 5 nm. These are readily dispersible water, display...
A novel dual <italic>T</italic><sub>1</sub>/<italic>T</italic><sub>2</sub><sup>1</sup>H-MRI contrast agent based on the encapsulation of super-paramagnetic iron oxide nanoparticles (SPIONs) with an coordination polymer is proposed.
Au nanoclusters (Au NCs) are materials that hold great promise in biomedical applications due to their improved photophysical properties. However, the current nonthiolate polymer-based self-assembly methods for preparing NCs face drawbacks of usage environmentally unfriendly reducing reagents or nonbiocompatible polymers, which largely hamper more extensive use. In this work, biocompatible chitosan-graft-poly(l-lysine) (CPL) dendrons designed and synthesized based on a simple azide–alkyne...
Hydrogen (H 2 ) has been demonstrated to be highly effective in combating drug-resistant Staphylococcus aureus by breaking the redox homeostasis of bacterial metabolism and down-regulating expression many genes like fmtA , gpsB etc.