A5062249328- Protein Structure and Dynamics
- Bacteriophages and microbial interactions
- Nanocluster Synthesis and Applications
- Quantum Dots Synthesis And Properties
- Molecular Sensors and Ion Detection
- Advanced Cellulose Research Studies
- Photochromic and Fluorescence Chemistry
- Advanced Drug Delivery Systems
- biodegradable polymer synthesis and properties
- Algal biology and biofuel production
- Enzyme Catalysis and Immobilization
- Enzyme Structure and Function
- Luminescence and Fluorescent Materials
- Wound Healing and Treatments
- Photosynthetic Processes and Mechanisms
- Vagus Nerve Stimulation Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Bacterial Genetics and Biotechnology
- Heat Transfer and Optimization
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Drug Transport and Resistance Mechanisms
- Proteins in Food Systems
- Metalloenzymes and iron-sulfur proteins
- Biofuel production and bioconversion
Indian Institute of Science Education and Research Mohali
2018-2022
Institute of Nano Science and Technology
2017-2022
India Habitat Centre
2017-2020
Center for Nano Science and Technology
2020
Independent Sector
2019
Jamia Hamdard
2015
The aim of the present study was to improve bioavailability an important antiretroviral drug, Darunavir (DRV), which has low water solubility and poor intestinal absorption through solid dispersion (SD) approach incorporating polymer with P-glycoprotein inhibitory potential.A statistical where design experiment (DoE) used prepare SD DRV incorporation inhibitors. Using DoE, different methods preparation, like melt, solvent evaporation, spray drying method, utilizing carriers Kolliphor TPGS...
Bacterial microcompartments (MCPs) are polyhedral organelles containing an enzyme cluster wrapped inside a protein shell and carry out specific reactions in bacteria. These have been explored meticulously using genetic, structural, biochemical tools; however, their application material science has not much. In this study, we used the external surface of MCP as scaffold for fabrication gold nanoparticles displayed 3D. This resulted formation scaffolded nanoparticle enclosing active cluster....
Nanofluids play a very important role in thermal management and heat exchange processes for stable nanofluid, surfactant is salient material. There are many contrasting reports on the conductivity of nanofluids associated transport mechanism nanofluids. In this article, four different types nanoparticles synthesized using citric acid oleic as surfactants, followed by assessment their conductivities. For nanofluid 3 wt% nanoparticles, coated with water 67% reduction observed, other hand 4%...
Fabricating protein compartments from units is challenging and limited by the use of external stimuli crosslinkers. Here we explore fabrication all-protein using self-assembled proteins prokaryotic organelles. These have intrinsic interacting domains which are ionic in nature, spontaneously self-assemble into sheets when over-expressed. Using a one-step approach, maneuvered formation shells without any or crosslinker. The spontaneous self-assembly native not only preserves functional...
A proof-of-concept on temporal control in the tritylation reactions has been demonstrated using a designed tripodal triazole-linked azo(hetero)arene-based photoswitchable catalyst.
Age-related hearing loss (ARHL) is a common condition in humans marking the gradual decrease with age. Perturbations tip-link protein cadherin-23 that absorbs mechanical tension from sound and maintains integrity of associated ARHL. Here, search molecular origins for ARHL, we dissect conformational behavior along mutant S47P progresses drastically. Using an array experimental computational approaches, highlight lower thermodynamic stability, significant weakening hydrogen-bond network...
Design, synthesis and studies of light-induced shape-changing azomacrocycles for reversible modulation monomeric fluorescence emission pyrene.
A classic example of an all-protein natural nano-bioreactor, the bacterial microcompartment is a prokaryotic organelle that confines enzymes in small volume enveloped by outer protein shell. These compartments metabolize specific organic molecules, allowing bacteria to survive restricted nutrient environments. In this work, 1,2-propanediol utilization (PduMCP) was used as model study effect molecular confinement on stability and catalytic activity native microcompartment. combination enzyme...
Abstract A classic example of an all-protein natural nano-bioreactor, the bacterial microcompartments are a special kind prokaryotic organelles that confine enzymes within small volume enveloped by outer layer shell proteins. This arrangement provides conditional metabolic aid to bacteria. The allows selective diffusion molecules and sequesters toxic metabolites. In this work we use 1,2-propanediol utilization microcompartment as model study effect molecular confinement on stability...