A5051013000- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Transcranial Magnetic Stimulation Studies
- Tryptophan and brain disorders
- Electroconvulsive Therapy Studies
- Schizophrenia research and treatment
- Mental Health Research Topics
- Mental Health Treatment and Access
- Pain Management and Treatment
- Palliative Care and End-of-Life Issues
- Suicide and Self-Harm Studies
- Child and Adolescent Psychosocial and Emotional Development
- Functional Brain Connectivity Studies
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Sleep and Wakefulness Research
- Neurotransmitter Receptor Influence on Behavior
- Health Systems, Economic Evaluations, Quality of Life
- Alcoholism and Thiamine Deficiency
- Pharmacogenetics and Drug Metabolism
- Vitamin D Research Studies
- Psychiatric care and mental health services
- Psychotherapy Techniques and Applications
- Diet and metabolism studies
- Cardiac electrophysiology and arrhythmias
WinnMed
2015-2025
Mayo Clinic
2015-2025
Mayo Clinic in Arizona
2015-2025
Mayo Clinic in Florida
2010-2025
Sheppard Pratt Health System
2024
Cornell University
2024
Weill Cornell Medicine
2024
Hope University
2023
University of Cincinnati
2023
University of Minnesota System
2023
Background: Single infusions of ketamine have been used successfully to achieve improvement in depressed patients. Side effects during the common. It is not known whether serial or lower infusion rates result greater efficacy. Methods: Ten patients were treated with twice weekly 0.5 mg/kg administered over 100 min until either remission was achieved four given. assessed Young Mania Rating Scale (YMRS) and Brief Psychiatric (BPRS). Patients followed naturalistically at intervals for weeks...
Objective: Ketamine has been redeveloped as a rapid-acting antidepressant for treatment-resistant depression (TRD). There is paucity of literature comparing subanesthetic intravenous (IV) ketamine and US Food Drug Administration (FDA)-approved intranasal (IN) esketamine TRD in real-world clinical settings. We compared the efficacy time to achieve remission/response with repeated esketamine.Methods: An observational study adults received up 6 IV (0.5 mg/kg over 40 minutes) or 8 IN (56- 84-mg)...
We investigated the psychometric validity and reliability of Suicide Status Form‐II (SSF‐II) developed by Jobes, Jacoby, Cimbolic, Hustead (1997) . Participants were 149 psychiatric inpatients (108 suicidal; 41 nonsuicidal) at Mayo Clinic. Each participant completed assessment measures within 24 hours admission 48–72 later. Factor analyses SSF core produced a robust two‐factor solution reflecting chronic acute response styles. The had good to excellent convergent criterion validity; pre‐post...
Abstract Objectives Caregiving can negatively impact well‐being. Cancer caregivers face unique challenges given the intense nature of cancer and treatment, which increases their risk for burden, poor quality life (QOL), burnout. Studies to reduce caregiver burden demonstrate QOL improvement distress reduction in short term. However, few studies exist address long‐term benefits. We assessed changes various domains after participation a intervention patients having newly diagnosed advanced...
Abstract The objective of this study was to determine whether proteomic profiling in serum samples can be utilized identifying and differentiating mood disorders. A consecutive sample patients with a confirmed diagnosis unipolar (UP n =52) or bipolar depression (BP-I =46, BP-II =49) controls ( =141) were recruited. 7.5-ml blood drawn for multiplex 320 proteins utilizing the Myriad RBM Discovery Multi-Analyte Profiling platform. After correcting multiple testing adjusting covariates, growth...
We aimed to establish a bipolar disorder biobank serve as resource for clinical and biomarker studies of disease risk treatment response. Here, we describe the aims, design, infrastructure, research uses biobank, along with demographics features first participants enrolled.Patients were recruited Mayo Clinic Bipolar Biobank beginning in July 2009. The Structured Clinical Interview DSM-IV was used confirm diagnosis. Questionnaire Participant designed collect detailed demographic data,...
Bipolar disorder (BD) is highly heterogeneous in symptomatology. Narrowing the clinical phenotype may increase power to identify risk genes that contribute particular BD subtypes. This study was designed test hypothesis genetic overlap between schizophrenia (SZ) and higher for with a history of manic psychosis. Analyses were conducted using Mayo Clinic Biobank cohort 957 bipolar cases (including 333 psychosis during mania, 64 only depression, 547 no psychosis, 13 unknown psychosis) 778...
ABSTRACT Few studies have investigated the influence of optimism–pessimism in breast cancer survivors. This study used a retrospective design with 268 adult women who completed Minnesota Multiphasic Personality Inventory (MMPI) as part their medical care approximately 10 years prior to diagnosis and Medical Outcome Study Short-Form General Health Survey (SF-36 or SF-12), on average, 8 after diagnosis. MMPI pessimism scores were divided into quartiles, t tests determine differences between...
A number of antidepressant medications, as well electroconvulsive therapy, have been shown to reduce chronic pain. Slow-frequency repetitive transcranial magnetic stimulation (rTMS) applied the right dorsolateral prefrontal cortex has also an effect. Given high degree suffering experienced by subjects with neuropathic pain and treatment resistance noted in this population, use slow-frequency rTMS adjuvant therapy may be significant clinical benefit.Fifteen sessions 1-Hz (1600...
The burden associated with caregiving has been well documented. Caregivers have multiple responsibilities, and technology may be accessible as a potential burden-alleviating resource.