- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Insect symbiosis and bacterial influences
- Mosquito-borne diseases and control
- Aquaculture Nutrition and Growth
- Viral Infections and Vectors
- Studies on Chitinases and Chitosanases
- Heavy metals in environment
- Arsenic contamination and mitigation
- Physiological and biochemical adaptations
- Vector-borne infectious diseases
- Immune Response and Inflammation
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Plant Disease Resistance and Genetics
- Aluminum toxicity and tolerance in plants and animals
- Bacteriophages and microbial interactions
- Heavy Metal Exposure and Toxicity
- Rice Cultivation and Yield Improvement
- Kruppel-like factors research
- Mechanisms of cancer metastasis
- Advanced Frequency and Time Standards
- Turtle Biology and Conservation
- Cell Adhesion Molecules Research
- Chromium effects and bioremediation
Hohai University
2024-2025
Ministry of Agriculture and Rural Affairs
2025
Guangdong Academy of Agricultural Sciences
2025
South China Agricultural University
2020-2024
Wannan Medical College
2023
South China Botanical Garden
2022
Chinese Academy of Fishery Sciences
2008-2021
Qingdao National Laboratory for Marine Science and Technology
2016-2021
Shanghai Astronomical Observatory
2021
Shanghai Ocean University
2021
Vitellogenin (Vg), a major reproductive protein, has been associated with infection-resistant response in fish. However, the underlying mechanisms by which Vg is involved anti-infectious are not understood.By both protein-microbe interaction analysis and enzyme-linked immunosorbent assay as well phagocytosis test, we demonstrate for first time that fish acts pattern recognition molecule multiple specificities can recognize bacteria fungus rather than self components from fish, functions an...
Although anaplasmosis cases have been nationally identified in China, no human isolates of A. phagocytophilum obtained, which limits the analysis any molecular and genetic contributions to patients' severe clinical manifestations study bacteria's pathogeneses China. Given this situation, a joint project was conducted 2009–2010. A total 421 febrile unknown etiology were collected blood samples for laboratory diagnoses including serologic diagnosis based on four-fold rise anti- IgG titer by...
ABSTRACT Depression represents a condition characterized by cognitive deficits and neural dysfunction has recently been correlated with microRNAs (miRs) their respective target genes. The present study was conducted the goal of investigating expression miR‐192‐5p its gene fibulin (Fbln)‐2 in an attempt to evaluate roles occurrence progression impairment function mice chronic unpredictable mild stress (CUMS)–induced depression through regulation TGF‐β1 signal transduction pathway....
We explored the mechanism of definitive-stage ɛ-globin transcriptional inactivity within a human β-globin YAC expressed in transgenic mice. focused on globin CAC and CAAT promoter motifs, as previous laboratory clinical studies indicated pivotal role for these elements gene activation. A high-affinity CAC-binding site erythroid krüppel-like factor (EKLF) was placed at position corresponding to that adult promoter, thereby simultaneously ablating direct repeat (DR) element. This mutation led...
When the orphan nuclear receptors TR2 and TR4, DNA-binding subunits of DRED repressor complex, are forcibly expressed in erythroid cells transgenic mice, embryos exhibit a transient mid-gestational anemia as consequence reduction number primitive cells. GATA-1 mRNA is specifically diminished these TR2/TR4 it human CD34 + progenitor transfected with TR2/TR4. In contrast, loss-of-function studies analyzing either Tr2 - or Tr4 -germline-null mutant mice force-expressed TR4 short hairpin RNAs...
Abstract Background Spotted fever caused spotted group rickettsiae (SFGR) is prevalent throughout China. In this study, we describe a rapid, simple, and sensitive loop-mediated isothermal amplification (LAMP) assay targeting the ompB gene of ideal for application in The LAMP has potential to detect early infection could therefore serve as an alternative existing methods. Methods A set universal primers which are specific 7 common species China were designed using PrimerExplorer V4 software...
In order to study the influence of construction interfaces on safety middle-low and 100-m cemented sand gravel (CSG) dams, direct shear tests with laying mortar roughening under four different normal pressures are firstly conducted; stress–shear displacement curves interface parameters for models obtained. Then, finite element established using a modified Duncan–Chang constitutive model zero-thickness model. Displacements, stresses, anti-sliding stability coefficients obtained, load-bearing...
The first Agriculture-Vision Challenge aims to encourage research in developing novel and effective algorithms for agricultural pattern recognition from aerial images, especially the semantic segmentation task associated with our challenge dataset. Around 57 participating teams various countries compete achieve state-of-the-art agriculture segmentation. Agriculture- Vision Dataset was employed, which comprises of 21,061 multi-spectral farmland images. This paper provides a summary notable...
To inactivate chronically the β 2 -integrin CD11b (Mac-1), we made a transgenic model in mice which expressed antagonist polypeptide neutrophil inhibitory factor (NIF). Using these mice, determined vivo effects of inactivation on polymorphonuclear leukocyte (PMN) function and acute lung injury (ALI) induced by Escherichia coli septicemia. In wild-type PMNs, expression was within 1 h after E. challenge, whereas this response significantly reduced NIF +/+ PMNs. Coimmunoprecipitation studies...
ABSTRACT Anaplasma phagocytophilum is the causative agent of human granulocytic anaplasmosis, which prevalent throughout China. In this study, we describe a rapid, simple, and sensitive loop-mediated isothermal amplification (LAMP) assay targeting msp2 gene A. that ideal for application in rural areas This has potential to detect early infection as an alternative existing methods. A total 42 suspected cases with , 15 serologically confirmed 27 probable cases, were analyzed by LAMP assay. To...
Abstract Rice straighthead disease substantially reduces crop yield, posing a significant threat to global food security. Dimethylarsinic acid (DMA) is the causal agent of and highly toxic reproductive tissue rice. However, precise physiological mechanism underlying DMA toxicity remains unknown. In this study, six rice varieties with varying susceptibility were utilized investigate growth performance element distribution in panicles under stress through pot experiments, as well explore...