A5087444351- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced Photocatalysis Techniques
- Click Chemistry and Applications
- Carbohydrate Chemistry and Synthesis
- Phytochemicals and Antioxidant Activities
- Pharmaceutical and Antibiotic Environmental Impacts
- Metal complexes synthesis and properties
- Crystallography and molecular interactions
- HIV/AIDS drug development and treatment
- TiO2 Photocatalysis and Solar Cells
- Cultural Heritage Materials Analysis
- Cholinesterase and Neurodegenerative Diseases
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced Nanomaterials in Catalysis
- Catalysis for Biomass Conversion
- Organometallic Complex Synthesis and Catalysis
- Biofuel production and bioconversion
- Computational Drug Discovery Methods
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Essential Oils and Antimicrobial Activity
- Microencapsulation and Drying Processes
- Synthesis and Biological Evaluation
- Analytical chemistry methods development
University of Lisbon
2016-2025
University of Trás-os-Montes and Alto Douro
2024
Institut des Sciences Moléculaires
2023
Instituto Superior Técnico
2012-2022
Instituto Politécnico de Lisboa
2015-2022
Rede de Química e Tecnologia
2008-2020
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento
1997-2020
Universidad Luterana Salvadoreña
2017
Universidade Federal do Ceará
2017
Petrobras (Brazil)
2013
Multicomponent oxide (i.e., SiO2-TiO2) microspheres with interconnected meso and macroporosity, called MICROSCAFS®, are attractive for various applications. Here, we present them as robust efficient catalyst supports, facilitating straightforward purification of wastewater through solar-driven photocatalysis, an easy recovery reuse. We report on the immobilization titanium dioxide (TiO2) gold nanoparticles (Au NPs) into MICROSCAFS® their characterization using analytical techniques. The...
The future widespread production of biomass-derived fuels, chemicals, and materials requires cost-effective processing sustainable feedstock. use imidazole as a solvent for biomass creates novel approach that helps to accomplish this idea in green fashion. This work proposes wheat straw pretreatment, which allowed the cellulose- hemicellulose-rich fractions added-value products from depolymerization lignin. Various temperatures (110, 140, 170 °C) times (1, 2, 4 h) pretreatment were...
The present work describes the facile synthesis, full characterization, and architectural diversity of three new bioactive silver-organic networks, namely 1D [Ag2(μ-PTA)2(μ-suc)]n·2nH2O (1), 2D [Ag2(μ-PTA)2(μ4-adip)]n·2nH2O (2), 3D [Ag2(μ4-PTA)(μ4-mal)]n (3) coordination polymers, generated via a mixed-ligand strategy using PTA (1,3,5-triaza-7-phosphaadamantane) as main building block flexible aliphatic dicarboxylic acids (succinic (H2suc), adipic (H2adip), or malonic (H2mal) acids) an...
Three novel bioactive silver–organic networks, namely, the 2D polymer [Ag(μ3-PTA)(chc)]n·n(Hchc)·2nH2O (1), 3D bioMOF [Ag2(μ3-PTA)2(μ2-chdc)]n·5nH2O (2), and [Ag2(μ2-PTA)2(μ4-H2chtc)]n·6nH2O (3), were constructed from 1,3,5-triaza-7-phosphaadamantane (PTA) various flexible cyclohexanecarboxylic acids as building blocks {cyclohexanecarboxylic (Hchc), 1,4-cyclohexanedicarboxylic (H2chdc), 1,2,4,5-cyclohexanetetracarboxylic (H4chtc) acid, respectively}. The obtained products 1–3 fully...
Several types of PCL, PLA, PDO, PET and PBT plastic waste were efficiently converted into value-added compounds fuels catalyzed by MoO<sub>2</sub>Cl<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>.
The laccase-catalysed oxidative coupling of substituted aromatic amines is described, extending the scope laccases towards production phenazine and phenoxazinone derivatives.
Environmental monitoring, particularly of water, is crucial to screen and preselect potential hazardous substances for policy guidance risk minimisation strategies. In Portugal, extensive data are missing. This work aimed perform a qualitative survey antibiotics in surface- groundwater, reflecting demographic, spatial, consumption drug profiles during an observational period three years. A passive sampling technique (POCIS) high-resolution chromatographic system were used monitor analyse the...
The development of sustainable biomaterials and surfaces to prevent the accumulation proliferation viruses bacteria is highly demanded in healthcare areas. This study describes assembly full characterization two new bioactive silver(I) coordination polymers (CPs) formulated as [Ag(aca)(μ-PTA)]n·5nH2O (1) [Ag2(μ-ada)(μ3-PTA)2]n·4nH2O (2). These products were generated by exploiting a heteroleptic approach based on use different adamantoid building blocks, namely...
Anthrax is an infectious disease caused by Bacillus anthracis, a bioterrorism agent that develops resistance to clinically used antibiotics. Therefore, alternative mechanisms of action remain challenge. Herein, we disclose deoxy glycosides responsible for specific carbohydrate-phospholipid interactions, causing phosphatidylethanolamine lamellar-to-inverted hexagonal phase transition and acting over B. anthracis cereus as potent selective bactericides. Biological studies the synthesized...
Abstract Many plants have medicinal properties due to substances known as phytochemicals. To utilize these in practice, numerous procedures, such extraction, isolation and characterization methods toxicology bioactivity studies, must be designed implemented. Integrated approach process Carpobrotus edulis , a weed plant widely spread Portugal, was developed into closed loop of two processes: microwave assisted extraction (MAE) activation (MAA), produce both phytochemicals biochar. The use MAE...
Pineapple peel still contains an important amount of phenolic compounds and vitamins with valuable antioxidant activity. In this way, the aim study was recovery bioactive from pineapple using environmentally friendly low-cost techniques, envisaging their application in food products. From solid-liquid extraction conditions tested, one delivering extract higher total content capacity a single step solvent-pineapple ratio 1:1 (w/w) for 25 min at ambient temperature, ethanol-water (80–20%) as...
Advanced oxidation processes, including photocatalysis, have been proven effective at organic dye degradation. Tailored porous materials with regulated pore size, shape, and morphology offer a sustainable solution to the water pollution problem by acting as support grafted photocatalytic nanoparticles (NPs). This research investigated influence of particle sizes MICROSCAFS® on degradation methyl orange (MO) in aqueous (10 mg/L). Photocatalytic are made binder-less supported P25 TiO2 NPs...
The new bis-iminopyrrolyl five-coordinate Co(II) complexes [Co(kappa (2) N, N'-NC 4H 3C(R)N-2,6- (i)Pr 2C 6H 3) 2(PMe 3)] (R = H 3a; Me 3b) were synthesized in high yields (ca. 80-90%), using THF and diethyl ether as solvents, respectively, by (a) treatment of CoCl 2 with the corresponding iminopyrrolyl Na salts ( Ie or If) (b) reaction anhydrous PMe 3 If. A third route was tested, involving addition excesses to 2] 1e; 1f), which only successful for synthesis 3a, lower 30%). 3b unfruitful...
Nevirapine (NVP) is a non-nucleoside reverse transcriptase inhibitor used against human immunodeficiency virus type-1 (HIV-1), mostly to prevent mother-to-child HIV-1 transmission in developing countries. Despite its clinical efficacy, NVP administration associated with variety of toxic responses that include hepatotoxicity and skin rash. Although the reasons for adverse effects are still unclear, increasing evidence supports involvement metabolic activation reactive electrophiles. In...
In this study, we successfully addressed the challenges posed by identification of dyes in medieval illuminations. Brazilwood pigment lakes and orcein purple colours were unequivocally identified illuminated manuscripts dated art historians to be from thirteenth fifteenth centuries Fernão Vaz Dourado Atlas (sixteenth century). All three works on a parchment support. This was possible combining Raman microscopy surface-enhanced spectroscopy with microspectrofluorimetry. To best our knowledge,...