- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Cancer Treatment and Pharmacology
- Metastasis and carcinoma case studies
- Microstructure and Mechanical Properties of Steels
- Gastrointestinal Tumor Research and Treatment
- Cancer Genomics and Diagnostics
- Corrosion Behavior and Inhibition
- Genetic factors in colorectal cancer
- Hydrogen embrittlement and corrosion behaviors in metals
- Cancer Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Chemotherapy-related skin toxicity
- Anorectal Disease Treatments and Outcomes
- Abdominal Surgery and Complications
- Plant-based Medicinal Research
- Metallurgical Processes and Thermodynamics
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- Ovarian cancer diagnosis and treatment
- Stoma care and complications
Fukuoka University
1978-2024
Fukuoka University Hospital
2021-2024
Tokyo Women's Medical University
2019
JFE Holdings (Japan)
2015
University of Fukui
2011
Osaka National Hospital
2006
The University of Tokyo
1997
Osaka International Cancer Institute
1990
We studied the behaviors of contrast in backscattered electron (BSE) images cross-sectional heat-treated steel under various accelerating voltages and take-off angles. Changes these conditions resulted dramatic changes contrast. Low voltage low angle improved surface information channeling contrast, whereas high enhanced bulk reduced resulting Z Such behavior can be understood by ratio low-loss electrons (LLEs), which are related to inelastic BSE components detected. The distribution varies...
Abstract Numbness and pain are currently evaluated using subjective methods such as the visual analogue scale (VAS). PainVision (PV) is an analytical instrument that was designed to quantitatively assess sense perception nociception in patients. Chemotherapy-induced peripheral neuropathy (CIPN) one of most important adverse events renders prolonged chemotherapy difficult. To features CIPN, we aimed compare PV with existing methods. A total 73 patients received oxaliplatin for metastatic...
In the process of hot dip galvanizing high tensile strength sheet steels containing Si and Mn, selective surface oxidation Mn causes coating defects. One promising method for overcoming this problem is an oxidation-reduction process. When steel exposed to oxidizing atmosphere, it will react primarily by forming Fe oxide, which can be reduced hydrogen in a reduction that follows. It has been explained good wettability obtained due formation pure iron. However, mechanism suppression not...
The influence of the Si/Mn ratio on galvannealing behavior 1.5 wt% Si −1.5~2.5 Mn-added steel in Fe oxidation-reduction process was investigated. affected formation Si-containing oxides during annealing process. amount SiO2 formed surface decreased with as decreased, while Mn2SiO4 increased. In addition, internal oxide a relatively narrow area near lower sample, which indicated that content solute sample. reaction accelerated by decreasing steel. species and morphology determined Si-added...
Background/Aim: Self-expandable metallic stent (SEMS) placement is becoming the standard bridge-to-surgery (BTS) strategy for potentially curable left-sided obstructive colorectal cancer (OCRC). The study objective was to evaluate effectiveness of SEMS as a BTS both right- and OCRC. Patients Methods: We retrospectively compared short- long-term outcomes patients with OCRC who underwent versus trans-nasal/anal decompression tube (DCT). cohort comprised 57 stage II/III right-sided (DCT, n=20;...
In the process of hot dip galvanizing Si and Mn added high tensile strength sheet steels, selective surface oxidation causes coating defects. One promising methods overcoming this problem is oxidation-reduction process. The steel exposed to an oxidizing atmosphere will react primarily by forming mainly iron oxide, which can be reduced hydrogen in following reduction It has been explained that due formation pure iron, good wettability obtained. However, mechanism suppression not clarified...
Abstract Capecitabine is selectively converted from 5′-DFUR to 5-fluorouracil (5-FU) in tumours by thymidine phosphorylase (TP). We investigated the addition of 5-nitrouracil (5-NU), a TP inhibitor, into blood samples for precise measurements plasma 5-FU concentrations. The concentration was measured after capecitabine administration. Two were obtained at 1 or 2 h administration and 5-NU added one each pair. Samples stored room temperature 4 °C concentrations immediately 1.5 3 later. mean...
Abstract The transanal and transperineal endoscopic approaches are useful advanced surgical options for removing rectal anorectal cancers. Intraoperative carbon dioxide (CO 2 ) embolisms, however, have been increasingly reported as potentially fatal complications associated with surgery employing these approaches. We report our experience a CO embolism that was detected because of sudden drop in end‐tidal decreasing saturation percutaneous arterial oxygen during total pelvic exenteration...
The detection of circulating cell-free DNA (cfDNA) by liquid biopsy is reported to provide prognostic information in colorectal cancer (CRC). Although the frequency BRAF V600E mutation CRC less than 10%, it associated with poor responses conventional chemotherapy. We conducted a prospective study investigate relationship between perioperative mutant allele (MAF) and tumor recurrence, evaluate possibility early recurrence. Among 362 patients who underwent radical resection, cfDNA was...
Abstract Background The detection of circulating tumor DNA (ctDNA) in colorectal cancer (CRC) by liquid biopsy may have prognostic information. In this perioperative study, we evaluate if there is a relationship between mutant allele frequency (MAF) Kirsten rat sarcoma viral oncogene homolog ( KRAS ) and recurrence how that could be useful the early recurrence. Methods Among 304 cases surgery, ctDNA was sampled from blood 84 patients with CRC mutation (exon 4 p.A146T, exon p.A146V, 2 p.G12A,...
The behaviors of contrasts in backscattered electron (BSE) images cross-sectional heat-treated steel are studied under various accelerating voltages and take-off angle conditions. Changes these conditions resulted dramatic changes contrasts. Low low angles improve surface information channeling contrasts, whereas high enhance bulk reduce resulting improved Z contrast. These can be understood by the ratio LLE (Low-Loss Electron), which related to inelastic BSE components detected....
Background Accurate lymph node evaluation is essential for staging colon cancer and guiding postoperative treatment decisions. In this study, we compared the efficacy of a simple enzymatic fat dissolution method with conventional sampling from specimens after surgery. Methods We enrolled 58 patients who underwent elective laparoscopic surgery adenocarcinoma between May 2018 2021 at Fukuoka University Hospital in Fukuoka, Japan. The these were treated using which manual palpation was used....
症例は69歳の女性で,肛門痛を主訴に当院を受診した.肛門周囲に全周性の発赤とびらんを認め,下部消化管内視鏡検査で肛門管内に隆起性病変を認めた.肛門皮膚のびらんからの生検にて印環細胞癌と診断され,Paget現象を伴う原発性肛門管癌と考えた.造影CTにて右鼠径部にリンパ節の腫大を認め,経会陰内視鏡アプローチ併用腹腔鏡下直腸切断術,右鼠径リンパ節郭清を施行した.病理組織学検査では肛門皮下に異型上皮細胞の充実胞巣と一部に中分化型腺癌を認め,表皮内に印環細胞様形態の癌細胞が進展していた.免疫組織学的染色では皮下の癌胞巣と表皮内の進展部位にCK7,CK20,CDX2,synaptophysinが陽性で,GCDFP-15,GATA3が陰性であったこと,また腺癌成分が20%程度であったことから,Paget現象を伴う肛門管原発神経内分泌癌と診断した.術後3か月で肝転移再発を認め,1年5か月で癌死した.
The present study reviewed cases of Toxic megacolon (TM) treated in our department, summarized the timing and technique surgery, considered key points for surgical management.
Abstract Background Neurofibromatosis type 1 (NF1) is known to be associated with the frequent occurrence of unique gastrointestinal stromal tumors (GISTs), preferably occurring in small intestine, no mutations c-kit proto-oncogene or platelet-derived growth factor receptor-alpha (PDGFRA), a high tendency for multifocal development, indolent nature, low proliferation activity and favorable prognosis. Case presentation A woman her forties visited local doctor complaining menstrual pain; large...