A5011263532- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
- Anesthesia and Neurotoxicity Research
- Thermal Regulation in Medicine
- Anesthesia and Pain Management
- Cancer, Stress, Anesthesia, and Immune Response
- Trauma Management and Diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Asthma and respiratory diseases
- Anesthesia and Sedative Agents
- Spine and Intervertebral Disc Pathology
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Cardiac Ischemia and Reperfusion
- Cardiovascular Health and Disease Prevention
- Inhalation and Respiratory Drug Delivery
- Medical Practices and Rehabilitation
- Congenital Diaphragmatic Hernia Studies
- Pharmacological Receptor Mechanisms and Effects
- Cardiac Arrhythmias and Treatments
- Biomedical and Chemical Research
- Hemodynamic Monitoring and Therapy
Otto-von-Guericke University Magdeburg
2007-2021
Uppsala University
2009-2021
Yahoo (United Kingdom)
2021
Committee on Publication Ethics
2021
University of Amsterdam
2015-2018
Amsterdam UMC Location University of Amsterdam
2015-2018
Leipzig University
2018
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015
Chongqing Electromechanical Holdings (China)
2015
San Diego Cardiac Center
2011
Mechanical ventilation (MV) may induce an inflammatory alveolar response. One-lung (OLV) with tidal volumes (Vt) as used during two-lung is a suggested algorithm but impose mechanical stress of the dependent lung and potentially aggravate mediator release. We studied whether different Vt modifies pulmonary immune function, hemodynamics, gas exchange. Thirty-two patients undergoing open thoracic surgery were randomized to receive either MV = 10 mL/kg (n 16) or 5 adjusted normal Pa(CO2) after...
One-lung ventilation (OLV) results in alveolar proinflammatory effects, whereas their extent may depend on administration of anesthetic drugs. The current study evaluates the effects different volatile anesthetics compared with an intravenous and relationship between pulmonary systemic inflammation patients undergoing open thoracic surgery.Sixty-three scheduled for elective surgery were randomized to receive anesthesia 4 mg · kg⁻¹ h⁻¹ propofol (n = 21), 1 minimum concentration desflurane or...
The increased tidal volume (V(T)) applied to the ventilated lung during one-lung ventilation (OLV) enhances cyclic alveolar recruitment and mechanical stress. It is unknown whether maneuvers (ARMs) reduced V(T) may influence density. Therefore, effects of ARM OLV with different on pulmonary gas/tissue distribution are examined.Eight anesthetized piglets were mechanically (V(T) = 10 ml/kg). A defined was whole (40 cm H(2)O for s). Spiral computed tomographic scans acquired before after ARM....
This review presents a brief overview of the non-analgetic effects thoracic epidural anaesthesia. It covers cardiac, pulmonary and gastrointestinal The results newer studies are particular importance regarding mortality major morbidity after anaesthesia.The clinical anaesthesia mainly attributed to transient sympathetic block affecting different organs. Furthermore, local anaesthetic itself reabsorbed from space may contribute Experimental have suggested that attenuate perioperative stress...
Transfusion of blood products and mechanical ventilation with injurious settings are considered risk factors for postoperative lung injury in surgical Patients.A systematic review individual patient data meta-analysis was done to determine the independent effects peri-operative transfusion products, intra-operative tidal volume airway pressure adult patients undergoing general surgery, as well their interactions on occurrence acute respiratory distress syndrome (ARDS). Observational studies...
Abstract Background Increasing numbers of patients with obstructive lung diseases need anesthesia for surgery. These conditions are associated pulmonary ventilation/perfusion (VA/Q) mismatch affecting kinetics volatile anesthetics. Pure shunt might delay uptake less soluble anesthetic agents but other forms VA/Q scatter have not yet been examined. Volatile anesthetics higher blood solubility would be affected by mismatch. We therefore compared and elimination isoflurane desflurane in a...
This article contains data on experimental endpoints of a randomized controlled animal trial. Fourteen healthy piglets underwent mechanical ventilation including injurious one-lung (OLV), seven them experienced four cycles remote ischemic preconditioning (RIP) one hind limb immediately before OLV, did not receive RIP and served as controls, in manner. The two major were (1) pulmonary damage assessed with the diffuse alveolar (DAD) score (2) inflammatory response by cytokine concentrations...
In der anästhesiologischen Praxis haben Atemwegs- und Lungenerkrankungen einen hohen Stellenwert. Das pulmonale System wird sowohl durch die Allgemein- als auch Regionalanästhesie erheblich beeinflusst. Dies lässt sich deutlich häufiger auftretende perioperative Komplikationen bei pulmonalen Risikopatienten im Vergleich mit Lungengesunden nachweisen. Die Durchführung einer Anästhesie Patienten Asthma muss verschiedene klinische Aspekte berücksichtigen. Diese beruhen v. a. auf Erkrankung des...