A5020470808- Food Allergy and Anaphylaxis Research
- Drug-Induced Adverse Reactions
- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Allergic Rhinitis and Sensitization
- Metabolism and Genetic Disorders
- Respiratory and Cough-Related Research
- Contact Dermatitis and Allergies
- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Autoimmune Bullous Skin Diseases
- Pharmaceutical studies and practices
- Immunodeficiency and Autoimmune Disorders
- Pediatric health and respiratory diseases
- Porphyrin Metabolism and Disorders
- Dermatology and Skin Diseases
- Biochemical and Molecular Research
- Neonatal Health and Biochemistry
- Blood disorders and treatments
- Genomic variations and chromosomal abnormalities
- Mitochondrial Function and Pathology
- Cutaneous lymphoproliferative disorders research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatological and Skeletal Disorders
- Cardiac Arrhythmias and Treatments
Memorial Ankara Hospital
2015-2025
Sağlık Bilimleri Üniversitesi
2017-2025
Bilkent University
2022-2025
University of Health Science
2020-2025
Ankara University
2020-2025
Ministry of Health
2014-2024
Ankara Bilkent City Hospital
2024
University of Health Sciences
2020-2024
Children's Hospital
2024
University of Health Sciences Antigua
2023
To address the problems about correct use of inhaler devices, adherence to corticosteroid treatment and effects these on control asthma.Children with asthma were evaluated for devices therapy using a questionnaire. Effect was defined.A hundred seventy-one patients and/or their families interviewed. The mean age 8.29 ± 4.65 years (1-19) 62.6% male. Metered dose (MDI) spacer used by 119 (69.5%) 52 (30.5%) dry powder inhalers (DPIs). correctly 68.1% MDI 34.6% DPI (p < 0.001). most common...
Skin testing has a limited role in the diagnosis of non-immediate beta-lactam hypersensitivity children. The aim this study was to report results oral provocation tests performed without skin children with mild cutaneous reactions systemic symptoms caused by antibiotics.Oral suspected antibiotics were patients antibiotics. not before tests. A total five doses administered half-an-hour intervals increasing doses. Provocation continued for 5 days.A 119 median age 4.3 (IQR: 2-7.5) years, whom...
Objective: Allergic diseases are characterized by a T-helper type 2 (Th2) dominant immune response, whereas juvenile idiopathic arthritis (JIA) is an autoimmune condition attributed to the Th1 pathway of CD4+ T cells. Reciprocal inhibition between and Th2 responses proposed result in mutual exclusion their polarized associated diseases. This study aimed ascertain frequency allergic among children with JIA. Methods: The International Study Asthma Allergies Childhood (ISAAC) questionnaire was...
Background: Antibiotic allergy in children is often misdiagnosed. The criterion standard for confirming drug the provocation test (DPT) based on patient's history and clinical findings. Objective: This study aimed to assess whether characteristics severity grades of index reaction can accurately predict DPT outcomes with suspected antibiotic allergy. Methods: A retrospective was conducted from 2014 2024, which included immediate-type reactions. Data age, type, duration, reactions,...
Background: Cephalosporins are beta-lactam antibiotics commonly used in children and the second most common cause of drug hypersensitivity reactions after penicillins. Antibiotic allergy is diagnosed by tests such as prick intradermal skin provocation test (DPT). Skin can be challenging for both patients clinicians. In appropriate cases, omitting these favour direct DPT may help to avoid diagnostic delays. Objective: Our study aimed evaluate results with a history mild cutaneous...
The dietary protein proctocolitis, also known as allergic proctocolitis (AP), is characterized by the presence of mucoid, frothy, and bloody stools in an otherwise healthy infant. aim this study was to describe a group children with AP, diagnosed according criterion-standard method, food challenge provide clinicians more information on typical presentation, overview nutritional management strategies prognosis.We collected data infants AP our allergy gastroenterology outpatient clinics. Any...
Chronic urticaria (CU) is a skin disorder defined as daily or almost exhibition of pruritic and transient wheals that last for 6 weeks. CU divided into two subtypes: chronic spontaneous (CSU) inducible (CIndU).To evaluate the clinical features, possible causes, associated findings, laboratory results different subtypes in children according to new classification.In this study, we evaluated investigations, provocation tests with classification.Two hundred twenty-two (59.9% girls) were...
<b><i>Background:</i></b> The incidence of rash after aminopenicillin treatment in children with Epstein-Barr Virus (EBV) infection was reported to be 80–100%. A few recent studies suggested that the may much lower during EBV infection. There are no clear data on true drug hypersensitivity among these patients. aim this study is determine and antibiotic allergy <b><i>Methods:</i></b> Drug investigated antibiotic-treated patients a positive IgM...
Nonsteroidal anti-inflammatory drugs (NSAID) are the second-most frequent that cause hypersensitivity reactions among children. Studies related to NSAIDs in children limited. In this study, we aimed evaluate admitted with suspicion of reaction.Between January 1, 2011, and November 30, 2014, included patients our clinic. For evaluation, skin tests oral provocation drug (suspected or alternative) were proposed. Reactions classified defined according latest European Academy Allergy Clinical...
The negative predictive value of the drug provocation test is important for both patient and physician. However, in children, this unresolved.The study included patients who had with a suspected was diagnosed as 'not allergic to drug'. Three months after allergy workup, were contacted asked reexposure tested drug. Patients have reported reactions during reevaluated skin tests provocation.During period, 217 provocations performed 203 patients. Of these, 163 (80.3%) 175 could be contacted....
Background and Objectives: Childhood asthma represents a significant global public health issue is the most common chronic disease among children. Hospitalization costs, especially for intensive care, are quite high. This study aimed to evaluate characteristics, prognosis, preventable risk factors of patients admitted Pediatric Intensive Care Unit (PICU) due severe exacerbations. Materials Methods: We assessed Ankara Bilkent City Hospital PICU from January 2013 December 2022 diagnosed with...
Background: The lung is one of the organs that can be damaged in patients with thalassemia major (TM). In this study, we aimed to evaluate pattern impairment using various pulmonary tests and effects transfusion on functions TM. Materials Methods: study was performed 9-21 years age prospectively. Spirometric tests, plethysmography, CO diffusion were before 2 h after erythrocyte transfusion. Patients also underwent a methacholine stimulation test Results: A total 37 TM included study. There...
Background: Sesame allergy has been seen with increasing frequency in recent years and is one of the important causes food anaphylaxis. Objective: The aim our study was to examine clinical laboratory features patients sesame evaluate characteristics sesame-related Methods: Patients diagnosed at Ankara Bilkent City Hospital between January 2017 June 2024 were included study. Demographic, data obtained from medical records. Results: allergies detected 70 during period. Of these patients, 44...
Steven Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but life-threatening severe cutaneous drug hypersensitivity reactions. The aim of our study was to evaluate the clinical features pediatric patients diagnosed with SJS, TEN or SJS/TEN overlap examine treatment modalities. Patients aged 0-18 years who were followed up at Ankara Bilkent City Hospital between August 2019 January 2024 retrospectively analyzed. Twelve met inclusion criteria included in study. Five had...
Cow's milk protein allergy (CMPA) is early life's most common food allergy. There limited data on the development of respiratory allergies in childhood for infants with CMPA. This study aimed to evaluate allergic diseases according mechanism CMPA patients first two years life. Patients who were diagnosed life and over five old during period included study. The sociodemographic, clinical, laboratory recorded, status disease was assessed using ISAAC questionnaire. A total 301 study; 182...