A5027723310- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Osteoarthritis Treatment and Mechanisms
- Elbow and Forearm Trauma Treatment
- Adhesion, Friction, and Surface Interactions
- Advanced Sensor and Energy Harvesting Materials
- TGF-β signaling in diseases
- Dental Implant Techniques and Outcomes
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Cardiovascular Effects of Exercise
- Electrical Contact Performance and Analysis
- Cardiomyopathy and Myosin Studies
- Cell Adhesion Molecules Research
- Orthopaedic implants and arthroplasty
- Mechanics and Biomechanics Studies
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Dental materials and restorations
- Conducting polymers and applications
- Cardiac Structural Anomalies and Repair
- High-Velocity Impact and Material Behavior
Boston University
2018-2024
University of Pittsburgh
2020-2023
Binghamton University
2016-2018
BackgroundPulmonary hypertension (PH) results in increased right ventricular (RV) afterload and remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug, composed of the neprilysin inhibitor sacubitril angiotensin receptor blocker valsartan, that has shown promising outcomes reducing risk death hospitalization for chronic systolic left heart failure. In this study, we aimed to examine if receptor-neprilysin inhibition using sac/val attenuates RV remodeling PH.Methods ResultsRV...
Healthy aging has been associated with alterations in pulmonary vascular and right ventricular (RV) hemodynamics, potentially leading to RV remodeling. Despite the current evidence suggesting an association between function higher prevalence of hypertension elderly, limited data exist on age-related differences structure biomechanics. In this work, we report our preliminary findings effects healthy structure, function, biomechanical properties. Hemodynamic measurements, biaxial mechanical...
Much of our understanding the role elbow ligaments to overall joint biomechanics has been developed through in vitro cadaver studies using motion simulators. The principle superposition can be used indirectly compute force contributions during prescribed motions. Previous have analyzed contribution different soft tissue structures stability human joints, but limitations evaluating loads sustained by those tissues. This paper introduces a unique, hybrid experimental-computational technique...
The ability to maintain living articular cartilage tissue in long-term culture can serve as a valuable analytical research tool, allowing for direct examination of mechanical or chemical perturbations on behavior. A fundamental challenge this technique is the recreation salient environmental conditions synovial joint that are required native homeostasis. Interestingly, conventional media formulations used explanted investigations often consist levels metabolic mediators deviate greatly from...
Abstract Right ventricular (RV) remodeling and longitudinal fiber reorientation in the setting of pulmonary hypertension (PH) affects structure function, eventually leading to RV failure. Characterizing kinematics myocardial fibers helps better understanding underlying mechanisms realignment PH. In current work, high-frequency ultrasound imaging structurally-informed finite element (FE) models were employed for an exploratory evaluation stretch-induced fibers. Image-based experimental...
Energy harvesting using a triboelectric nanogenerator (TENG) has been major area of research in the recent years order to harvest mechanical energy different scales. High conversion efficiency, broad range application systems and relatively easy fabrication process are among factors demonstrating essential needs for TENG technology development. Performance could be affected by many such as frequency vibration surface charge density. As key factor improving power output TENGs, density...
The durability of an implant-bone structure depends mainly on the capability implants and bone-implant interface to support masticatory forces. mechanical behavior both bone implant varies from one configuration another thus, it is still attractive topic for many researchers in dental biomechanics. This paper investigated stress distribution four different applications/configurations commercial by employing three dimensional finite element analyses. Fatigue analysis was also conducted...
Abstract Healthy aging has been associated with alterations in pulmonary vasculature and right ventricular (RV) hemodynamics, potentially leading to RV remodeling. Despite the current evidence suggesting an association between function higher prevalence of hypertension elderly, limited data exist on age-related differences structure biomechanics. In this work we report our preliminary findings effects healthy structure, function, biomechanical properties. Hemodynamic measurements, biaxial...