- Bioinformatics and Genomic Networks
- Genomics and Phylogenetic Studies
- Gene expression and cancer classification
- vaccines and immunoinformatics approaches
- RNA and protein synthesis mechanisms
- Antimicrobial Peptides and Activities
University of California, Davis
2024
Nile University
2020
Irber et al., (2024). sourmash v4: A multitool to quickly search, compare, and analyze genomic metagenomic data sets. Journal of Open Source Software, 9(98), 6830, https://doi.org/10.21105/joss.06830
1 Abstract Long-read sequencing (LRS) enables variant calling of high-quality structural variants (SVs). Genotypers SVs utilize these precise call sets to increase the recall and precision genotyping in short-read (SRS) samples. With extensive growth availabilty SRS datasets recent years, we should be able calculate accurate population allele frequencies SV. However, reprocessing hundreds terabytes raw data genotype new is impractical for population-scale studies, a computational challenge...
Codon optimization is primarily used in enhancing the levels of protein expression host species. Each species has its own codon usage bias, which represents codons abundance frequency that Using profile contributes to personalize synthesis DNA vaccines can achieve highly active vectors cells. For optimizing a particular host, genetic code sequence needs correction bias match landscape rather than donating organism profile. In this work, we have applied two approaches for protein-coding...