A5086480161- Frailty in Older Adults
- Nutrition and Health in Aging
- Dementia and Cognitive Impairment Research
- Palliative Care and End-of-Life Issues
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and Mental Health
- Cancer survivorship and care
- Nutritional Studies and Diet
- Health disparities and outcomes
- Long-Term Effects of COVID-19
- Aging, Elder Care, and Social Issues
- Blood Pressure and Hypertension Studies
- Air Quality and Health Impacts
- COVID-19 Pandemic Impacts
- Management and Optimization Techniques
- Quality and Supply Management
- PI3K/AKT/mTOR signaling in cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related cognitive impairment studies
- Political and Economic history of UK and US
- Ophthalmology and Visual Health Research
- Noise Effects and Management
- Hydrogen's biological and therapeutic effects
- Renin-Angiotensin System Studies
- RNA modifications and cancer
University of Southern California
2023-2025
All India Institute of Medical Sciences
2016-2024
Mays Cancer Center at UT Health San Antonio
2023
British Geriatrics Society
2023
KU Leuven
2023
The University of Texas Health Science Center at San Antonio
2023
Tata Memorial Hospital
2023
Abstract Introduction Prior estimates of dementia prevalence in India were based on samples from selected communities, inadequately representing the national and state populations. Methods From Longitudinal Aging Study (LASI) we recruited a sample adults ages 60+ administered rich battery neuropsychological tests an informant interview 2018 through 2020. We obtained clinical consensus rating status for subsample ( N = 2528), fitted logistic model this subsample, then imputed all other LASI...
Introduction Alzheimer’s disease and related dementias can be considered the epidemic of 21st century. Particularly, predicted growth in size elderly populations low-income middle-income countries is expected to produce a dramatic surge dementia prevalence incidence. Although rising burden presents an urgent challenge for India, previous efforts study country have relied on non-representative samples geographically restricted regions. The Harmonised Diagnostic Assessment Dementia...
BACKGROUND/OBJECTIVES To provide high‐quality data on older adults in India that will enable an in‐depth study of late‐life cognition and dementia cross‐country analysis risk factors for cognitive aging dementia. DESIGN The Longitudinal Aging Study (LASI) is a nationally representative survey health, economic, social well‐being the Indian population aged 45 older. Its large sample more than 70,000 represents not only country as whole but also each state. LASI‐Diagnostic Assessment Dementia...
Abstract The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is a nationally representative in-depth study cognitive aging and dementia. We present publicly available dataset harmonized measures 4,096 adults 60 years age older India, collected across 18 states union territories. Blood samples were obtained to carry out whole blood serum-based assays. Results are included venous specimen datafile that can be linked LASI-DAD dataset. A global...
To estimate frailty prevalence and its relationship with the socio-economic regional factors health care outcomes.
Abstract INTRODUCTION As India's population ages, the prevalence of dementia is increasing rapidly, inducing higher need for informal caregivers a complex population. However, effects individuals' cognitive impairment on their caregivers' well‐being in India have not been well studied. METHODS We analyzed data from 4196 informants participants Longitudinal Aging Study India‐Diagnostic Assessment Dementia (LASI‐DAD). Informants' caregiving roles and well‐being, including stress, mental...
OBJECTIVES To assess the prevalence of diagnosed and undiagnosed hypertension their relationship to cognitive function in older adults India. DESIGN Longitudinal Aging Study India–Diagnostic Assessment Dementia (LASI‐DAD), an in‐depth national study late‐life cognition dementia. SETTING Geriatric hospitals respondentsʼ homes across 14 states PARTICIPANTS N = 2,874 individuals aged 60 years from LASI‐DAD. MEASUREMENTS Hypertension was identified by self‐report physician diagnosis or measured...
Cognitive aging is a complex phenomenon, which comprises various cognitive skills, broadly categorized into fluid and crystallized intelligence. Crystallized intelligence (gc) tends to be maintained, as opposed (gf), decline rapidly with age. The association of the two remains matter conjecture requiring further research.
The COVID-19 pandemic had large impacts on mental health; however, most existing evidence is focused the initial lockdown period and high-income contexts. By assessing trajectories of health symptoms in India over 2 years, we aim to understand effect later time periods characteristics a lower-middle income context.
Abstract In this article, the Asian Geriatric Oncology Society provides an overview on how to develop geriatric oncology services in clinical setting. This gives insight into rationale; key stakeholders; four essential components of services; multidisciplinary team and tumor boards; assessment screening protocols; data, research, audit; professional education, development, training; communication, awareness social medial utilization. second part we focus optimizing resource utilization...
Abstract Background: Patients (pts) with non-small-cell lung cancer (NSCLC) who do not achieve pathologic complete response (pCR) after neoadjuvant chemoimmunotherapy and surgery have a worse prognosis than those pCR, escalation of therapy for improved outcomes may be warranted. Pembrolizumab (pembro) is approved in several countries as monotherapy the adjuvant treatment pts NSCLC following pembro plus platinum-based chemotherapy (chemo) resection. V940 (mRNA-4157) novel, mRNA-based,...
The Harmonized Diagnostic Assessment of Dementia for Longitudinal Aging Study in India (LASI–DAD) is a population-representative, prospective cohort study late-life cognition and dementia. It part an ongoing international research collaboration that aims to measure understand cognitive impairment dementia risk by collecting set neuropsychological assessments informant reports, referred as the Cognitive Protocol (HCAP). LASI–DAD provides nationally representative data drawn from subsample...
Since the onset of COVID-19 pandemic, behavioural interventions to reduce disease transmission have been central public health policy worldwide. Sustaining individual protective behaviour is especially important in low-income and middle-income settings, where systems fewer resources access vaccination limited. This study seeks assess time trends India.Nationally representative, panel-based, longitudinal study.We conducted a panel survey Indian households understand how adoption behaviours...
Abstract Background Geriatric syndromes (GS) are multi‐factorial conditions that make older adults vulnerable to morbidities and poor outcomes. The main objective was observe the frequency of GS in patients with COPD. Methods A case‐control study conducted department a tertiary care hospital India evaluate geriatric including falls, cognitive impairment, frailty, functional urinary incontinence, malnutrition, depression COPD controls without factors having significant association occurrence...
ABSTRACT Background: Health-related quality of life (HRQoL) is a major concern for older patients with cancer. The goal cancer care in most maintaining the remaining years rather than prolonging survival. Objectives: We aimed to evaluate quality-of-life (QoL) domains treatment-naïve Materials and Methods: This cross-sectional observational study was done Outpatient Department Geriatric Medicine All India Institute Medical Science, New Delhi, from July 2015 June 2017. Treatment-naïve aged 60...
ABSTRACT Background: Low and middle-income countries like India anticipate rapid population aging increases in dementia burden. In India, screening scales originally developed other contexts need to be assessed for feasibility validity, given the number of different languages varying levels literacy education. Method: Using data from Longitudinal Aging Study India-Diagnostic Assessment Dementia (N = 4,028), we characterize performance Informant Questionnaire on Cognitive Decline Elderly...