A5041144100- Marine Sponges and Natural Products
- Microbial Natural Products and Biosynthesis
- Seaweed-derived Bioactive Compounds
- Bee Products Chemical Analysis
- Plant and animal studies
- Insect and Pesticide Research
- Fungal Biology and Applications
- Insect and Arachnid Ecology and Behavior
- Algal biology and biofuel production
- Phytochemistry Medicinal Plant Applications
- Biochemical and biochemical processes
- Marine and coastal plant biology
- Microbial Metabolic Engineering and Bioproduction
- Plant-Microbe Interactions and Immunity
- Microbial metabolism and enzyme function
- Allelopathy and phytotoxic interactions
- Plant Growth Enhancement Techniques
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Analytical chemistry methods development
- Phytochemistry and Bioactive Compounds
- Psychedelics and Drug Studies
- Biotechnology and Related Fields
- Essential Oils and Antimicrobial Activity
- Enzyme Catalysis and Immobilization
Universidade Federal do Amazonas
2023
Universidade de São Paulo
2009-2019
Universidad de Cádiz
2018
Scripps Institution of Oceanography
2016
University of California, San Diego
2016
Universidade de Ribeirão Preto
2012
Marine environment is one of the most important sources regarding natural products research. Besides, marine microorganisms have been denominated as a talented source for discovery new leads. Although association macroalgae and fungi has described ecological issues, there lack studies about seaweed endophytic fungi. In this context, goal study was to evaluate cytotoxic, antifungal antibacterial activities isolated from Brazilian Bostrychia tenella (J.V. Lamouroux) J. Agardh (Ceramiales,...
Bacterial strains isolated from attine ants showed activity against the insect specialized fungal pathogen Escovopsis and also human protozoan parasite Leishmania donovani. The bioassay guided fractionation of extracts cultures Streptomyces sp. ICBG292, exoskeleton Cyphomyrmex workers, led to isolation Mer-A2026B (1), piericidin-A1 (2) nigericin (3). Nigericin (3) presented high intracellular amastigotes L. donovani (IC50 0.129 ± 0.008 μM). puniceus ICBG378, workers Acromyrmex rugosus...
Marine natural products have currently been recognized as the most promising source of bioactive substances for drug discovery research. In this review, extraordinary metabolites from marine algae species are illustrated, well approaches their isolation and determination biological properties pharmaceutical potential. Furthermore, endophytic microorganisms (from algae) presented a new subject extensive investigation to find novel products, which make them potentially rich innovative candidates.
Terrestrial bacteria, especially actinomycetes, are known to be prolific producers of volatile compounds. We show here that bacteria from ocean sediments can also release complex bouquets volatiles. The actinomycete Salinispora tropica produces cyclohexenyl compounds not previously in nature, such as methyl cyclohex-2-ene-1-carboxylate (9), 2-(cyclohex-2-en-1-yl)acetate (10), (E/Z)-2-(cyclohex-2-en-1-ylidene)acetate (11/12), and related alcohols 8 13. These were identified by GC/MS confirmed...
This study describes the isolation and structural determination of two amides, isolated for first time: N,4-dihydroxy-N-(2'-hydroxyethyl)-benzamide (0.019%) N,4-dihydroxy-N-(2'-hydroxyethyl)-benzeneacetamide (0.023%). These produced by red macroalgae Bostrychia radicans, had their structures assigned NMR spectral data MS analyses. In addition, this chemical led to cholesterol, heptadecane, squalene, trans-phytol, neophytadiene, tetradecanoic hexadecanoic acids, methyl hexadecanoate...
Abstract The biocatalytic reduction of acetophenone derivatives was exploited by using algal biomass from Bostrychia radicans and B. tenella producing exclusively ( S )‐2‐phenylethanols with high enantiomeric excess (>99% ee). Bacterial populations associated were identified as the Bacillus genus. This report deals first investigations involving use marine bacteria algae for derivatives.
Abstract Four endophytic fungi isolated from the marine red alga Bostrychia radicans identified as Botryosphaeria sp. CBMAI 1197, Eutypella 1196, Hidropisphaera 1194 and Xylaria 1195 catalyzed asymmetric bioreduction of fluoroacetophenone derivatives 1-3 to corresponding fluorophenylalcohols 1a-3a. In reduction reactions 2,2,2-trifluoro-1-phenylethanone 1, all produced exclusively (S)-2,2,2-trifluoro- 1-phenylethanol 1a with > 99% ee. The fungus 1197 exhibited best enzymatic potential,...
Brevianamides A and C are isomeric cyclic peptides with several reported biological activities, isolated from diverse microorganisms.Currently, there has been no previous investigation of brevianamide fragmentation utilizing electrospray ionization mass spectrometry (ESI-MS).In this work experiments were carried out in the positive mode using two different spectrometers (low high resolution) an ESI source.Computational chemistry studies helped identify protonation sites based upon atomic...
The plant species Paullinia cupana Kunth (Sapindaceae), commonly known as guarana, originates from the central Amazonian Basin and has a long history of local use for its stimulant properties. It is currently commercialized worldwide health beneficial seeds chemical composition been extensively studied over years. However, chemistry guarana flowers, particularly nectar content, have barely investigated. From an ecological perspective, floral pollen are primary food rewards pollinators. In...