A5100392831- Antifungal resistance and susceptibility
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- High Altitude and Hypoxia
- Respiratory Support and Mechanisms
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Fungal Infections and Studies
- Cardiovascular and Diving-Related Complications
- Airway Management and Intubation Techniques
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Vitamin C and Antioxidants Research
- Antibiotics Pharmacokinetics and Efficacy
- Hemodynamic Monitoring and Therapy
- Inflammation biomarkers and pathways
- Family and Patient Care in Intensive Care Units
- Nutrition and Health in Aging
- Vestibular and auditory disorders
- Clinical Nutrition and Gastroenterology
- Ion Transport and Channel Regulation
- Ethics in medical practice
- Clusterin in disease pathology
- Health Systems, Economic Evaluations, Quality of Life
- Cell death mechanisms and regulation
China Medical University
2012-2024
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Dalian Institute of Chemical Physics
2021
Chinese Academy of Sciences
2021
Liaoning Cancer Hospital & Institute
2021
Icahn School of Medicine at Mount Sinai
2021
State Key Laboratory of Pollution Control and Resource Reuse
2013
Nanjing University
2013
Air Force Institute of Aviation Medicine Affiliated Hospital
2010-2012
Abstract Background: Ciprofol (HSK3486; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China), developed as a novel 2,6-disubstituted phenol derivative showed similar tolerability and efficacy characteristics propofol when applicated continuous intravenous infusion for 12 h maintenance sedation in previous phase 1 trial. The 2 trial was designed to investigate the safety, efficacy, pharmacokinetic of ciprofol patients undergoing mechanical ventilation. Methods: In this multicenter, open...
ObjectivesTo describe the epidemiology, microbiology and management of invasive Candida infection (ICI) in intensive care units (ICUs) China.
ObjectivesThe objectives of this study were to determine species distribution and in vitro antifungal susceptibility Candida isolates identified the multicentre China-SCAN invasive infection (ICI) intensive care units (ICUs) across China.
Abstract. Being the largest contributor to global source of fossil-fuel CO2 emissions, China's emissions need be accurately quantified and well understood. Previous studies have usually focused on amount national rarely discussed their spatiotemporal distributions, which are also crucial for both carbon flux management. In this study, we calculated from fossil fuel use industrial processes using provincial statistics then mapped those at 0.25° resolution a monthly basis. Several key steps...
In patients hospitalized in intensive care units (ICU), Candida infections are associated with increased morbidity, mortality and costs. However, previous studies reported confused risk factors for catheter-related bloodstream infection (CRCBSI). The objective was to describe the factors, microbiology, management outcomes of CRCBSI China-SCAN population.Patients ≥1 Candida-positive peripheral blood culture were selected from study. Peripheral catheter samples collected isolation. Patients...
Esophageal cancer (EC) is a common malignant disease in eastern countries. However, study of the metabolomic characteristics associated with other biological factors esophageal squamous cell carcinoma (ESCC) limited. Interleukin enhancer binding factor 2 (ILF2) and ILF3, double-stranded RNA-binding proteins, have been reported to contribute occurrence development various types malignancy. Nevertheless, underlying functions ILF2 ILF3 ESCC metabolic reprogramming never reported. This aimed...
To identify the epidemiology, treatments, outcomes, and risk factors for patients with early- or late-onset invasive candidiasis (EOIC LOIC) in intensive care units China. Patients were classified as EOIC (≤10 days) LOIC (>10 according to time from hospital admission IC onset distinct clinical characteristics. There 105 cases 201 this study. was related more severe conditions at ICU prior IC. Significantly, of Candida parapsilosis infection found than those EOIC. The mortality significantly...
TRPV3 is a temperature-sensitive, nonselective cation channel expressed prominently in skin keratinocytes. plays important roles hair morphogenesis and maintenance of epidermal barrier function. Gain-of-function mutations have been found both humans rodents are associated with loss, pruritus, dermatitis. Here, we study the mechanisms acid regulation by using site-directed mutagenesis, fluorescent intracellular calcium measurement, whole-cell patch-clamp recording techniques. We show that,...
Pain relief for patients in the intensive care unit (ICU) can improve treatment outcomes and reduce burden on doctors nurses. This study aims to report clinical analgesic sedative effects of nalbuphine sufentanil ICU patients.This retrospectively analyzed medical records 87 critically ill who received or infusion ICU, including demographic data, diagnosis, Acute Physiology Chronic Health Evaluation (APACHE) II, Critical Care Observation Tool (CPOT), Richmond Agitation-Sedation Scale (RASS),...
1 Department of Critical Care Medicine, Shengjing Hospital China Medical University, Shenyang, China. 2 Emergency, The Fourth Affiliated Drs. Zhao and Wang were responsible for methodology, formal analysis, software, resources, investigation. Dr. Zang was supervision. All the authors participated in draft writing, review, editing. have disclosed that they do not any potential conflicts interest. are co-corresponding authors.
Objective To evaluate the protection performances of a new type oxygen supply system against hypoxia. Methods Totally 6 rounds test were taken in hypobaric chamber and rapid decompression chamber.A dummy was applied tests of:① conventional performance under altitude simulation from ground to 10.0 km; ② pressurized 13.0 17.0 ③ km order ensure safety physiological tests.Four volunteers with individual equipment underwent of:④ continuous for 4.0 h;⑤ at 15.0 ⑥ km. Results The partial pressure...