Scientists are now increasingly interested in the flavonoid molecule naringenin due to broad spectrum of biological roles it conducts. Oximes and hydrazones were created employing derivatives naringenin-active substances 7-piperidinethoxy 7-morpholinethoxy contribute this research. The ability produced compounds bind BSA was determined by molecular docking their potential as medications assessed using various methods. Based on Lipinski's rule five, none hazardous or carcinogenic, blood-brain...

Abstract N , ′‐diethoxy‐4,4′‐azobis(pyridinium) hexafluorophosphate (DEAP) has been synthesized by alkylation of the corresponding ‐oxide and characterized. DEAP exhibits UV induced cis–trans isomerization with absorptions at around λ = 459 360 nm, respectively. The ability ion to act as a photoinitiator for cationic polymerization cyclohexene oxide ‐vinylcarbazole is demonstrated. initiation step involves decay excited state trans form salt homolytic bond rupture nitrogen–oxygen bond. Its...

Naringenin is a naturally occurring flavonoid and due to its broad spectrum of biological activities, including anticancer properties, has attracted scientific attention in recent years. To contribute these studies, we synthesized some new (±)‐naringenin cyclic aminoethyl derivatives, analyzed the cytotoxic anti‐proliferative properties them via 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2 H ‐tetrazolium bromide ( MTT ) assay, mitochondrial apoptosis signaling response gene expressions belong...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic elaboration of diosphenols. Replacement hydroxyl by halogenA. A. Ponaras and Omer ZaimCite this: J. Org. Chem. 1986, 51, 24, 4741–4743Publication Date (Print):November 1, 1986Publication History Published online1 May 2002Published inissue 1 November 1986https://pubs.acs.org/doi/10.1021/jo00374a053https://doi.org/10.1021/jo00374a053research-articleACS PublicationsRequest reuse permissionsArticle Views431Altmetric-Citations14LEARN ABOUT...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic elaboration of diosphenols. Part 3. Replacement enolic oxygen by hydrogenAnthony A. Ponaras, Omer Zaim, Yessica Pazo, and Lena OhannesianCite this: J. Org. Chem. 1988, 53, 5, 1110–1112Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March 1988https://pubs.acs.org/doi/10.1021/jo00240a039https://doi.org/10.1021/jo00240a039research-articleACS PublicationsRequest reuse permissionsArticle...

Abstract Four new macrocyclic compounds with thiophene ( L1 and L2 ) furan L3 L4 rings were synthesized characterized by IR, 1 H NMR, 13 C Q‐TOF spectral data. Macrocyclic amides , tested for ion transportation Na + K ions, also, antimicrobial activities investigated against the Gram‐negative Escherichia coli ATCC 25922, Gram‐positive Staphylococcus aureus 25923, Listeria monocytogenes 19115, Salmonella typhimurium 14028, Bacillus cereus bacteria, Candida albicans 10231 all amides.

Abstract Four novel macrocyclic compounds with furan and thiophene were synthesized, characterized by IR, 1 H NMR, 13 C Q‐TOF spectral data. Antimicrobial activities of these tested against Gram− Escherichia coli ATCC 25922 , E. O157 : H7ATCC 43895 Gram+ Staphylococcus aureus 25923 Listeria monocytogenes 19115 Salmonella typhimurium 14028 Candida albicans 10231 . Macrocyclic thioesters found more efficient selected microorganisms than other compounds, especially the thioester ring notably...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic elaboration of diosphenols. 2. Manifold pathways in the reaction cyclotene dimethylthiocarbamate with halide ionAnthony A. Ponaras and Omer ZaimCite this: J. Org. Chem. 1987, 52, 25, 5630–5633Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/jo00234a025https://doi.org/10.1021/jo00234a025research-articleACS PublicationsRequest reuse...

Abstract magnified image Treatment of pyridine N ‐oxides with dimethylthiocarbamoyl chloride in boiling acetonitrile effects chemoselective deoxygenation to pyridines.

A facile and efficient deoxygenation method for various amine N-oxides to their corresponding amines is described. The experimental procedure quite simple the products are obtained in excellent yields.

2-Azido and 2-thiocyanato-2,3-unsaturated ketones were synthesized by utilizing functionalization of 5- or 6-membered cycloalkane-1,2-diones, namely diosphenols, with dimethylthiocarbomoyl chloride, which activates the system towards reaction nucleophiles in acidic conditions. Replacement enolic oxygen diosphenols azide thiocyanate may be achieved treating their dimethylthiocarbamates sodium potassium boiling acetonitrile/acetic acid.

Several ring expansion products carrying vinylic bromo functionality were synthesized by opening of the geminal dibromobicyclo[n.1.0]alkanes ring. Dibromocarbene was formed from bromoform and potassium tert-butoxide in hexane. Its reaction with various cyclic alkenes resultant dibromobicyclo[n.1.0]alkanes. Then, performed using AgNO_3 solvent systems, such as acetic acid/DMSO, acid/DMF, CH_3OH/acetone, H_2O/DMF.

Cyclic polyethers, commonly known as crown ethers, were first synthesized by Pederson in 1967 [1,2].Crown ethers the synthetic molecules which could, virtue of their ability to assume a conformation resulting an electronrich cavity, function macrocyclic hosts, [3] Prior host/guest chemistry was restricted biologically active with cyclodextrins being most common.The oxygen atoms have been replaced sulfur, [4] nitrogen, [5] and ethyleneoxy units interchanged heterocycle such pyridine, furan,...

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Abstract Melting, recrystallisation and remelting of undrawn drawn linear polyethylene with different molecular weight were studied by differential scanning calorimetry before after oxidation nitric acid.