A5049114181- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Congenital Heart Disease Studies
- Medical Imaging and Pathology Studies
- Occupational and environmental lung diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MicroRNA in disease regulation
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Ischemia and Reperfusion
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Pleural and Pulmonary Diseases
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Coronary Artery Anomalies
- Vascular Procedures and Complications
- Pulmonary Hypertension Research and Treatments
Macquarie University
2013-2024
St George Hospital
2024
Australian Centre for Heart Health
2023-2024
Monash Health
2023-2024
The University of Adelaide
2024
The Ohio State University Wexner Medical Center
2020-2023
Victorian Heart Hospital
2023
Monash University
2023
Mount Sinai Hospital
2023
The Ohio State University
2020-2022
The presence of cell-free microRNAs (miRNAs) has been detected in a range body fluids. miRNA content plasma/serum particular proposed as potential source novel biomarkers for number diseases. Nevertheless, the quantification miRNAs from plasma or serum is made difficult due to inefficient isolation and lack consensus regarding optimal reference miRNA. effect haemolysis on normalisation not investigated great detail. We found that levels miR-16, commonly used gene, showed little variation...
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers for various diseases. Despite rapid progress this field, there remains lack consensus regarding optimal quantification methods, reference genes, quality control samples. Recent studies shown that hemolysis occurring during blood collection has substantial impact on the microRNA content plasma/serum. To date, only been investigated limited number microRNAs, mainly red cell (RBC)-enriched miRs-16 -451. In...
Fibulin-3 (FBLN3) was recently presented as a promising novel biomarker for malignant pleural mesothelioma (MPM), warranting independent validation studies. ELISA used to measure cellular and secreted FBLN3 in cell lines, plasma of xenograft tumour-bearing mice, from two series MPM non-MPM patients fluid third series. Diagnostic prognostic potential assessed by receiver operating characteristics curve analysis Kaplan–Meier method, respectively. expressed all benign mesothelial lines tested,...
// Marissa Williams 1, * , Michaela B. Kirschner 2, 13, Yuen Yee Cheng 1 Jacky Hanh 3 Jocelyn Weiss 4 Nancy Mugridge Casey M. Wright Anthony Linton 5 Steven C. Kao 6 J. James Edelman 7 Michael P. Vallely 7, 8 Brian McCaughan 9 Wendy Cooper 10 Sonja Klebe 11 Ruby C.Y. Lin 12 Himanshu Brahmbhatt Jennifer MacDiarmid Nico van Zandwijk 2 Glen Reid Asbestos Diseases Research Institute (ADRI), Sydney, Australia Sydney Medical School, The University of Faculty Pharmacy, EnGeneIC Ltd., Lane Cove,...
Purpose To show that the use of a multi‐velocity encoding (VENC) 4D‐flow approach offers significant improvements in characterization complex flow aorta. Four‐dimensional magnetic resonance imaging (MRI) (4D‐flow) can be used to measure patterns and dynamics heart major vessels. The quality information derived from these measures is dependent on accuracy vector field, which limited by vector‐to‐noise ratio. Materials Methods A protocol involving three different VENC values 150, 60, 20 cm/s...
Malignant pleural mesothelioma (MPM) is an aggressive, locally invasive, cancer elicited by asbestos exposure and almost invariably a fatal diagnosis. To date, we are one of the leading laboratory that compared microRNA expression profiles in MPM normal mesothelium samples order to identify dysregulated microRNAs with functional roles mesothelioma. We interrogated significant collection tumors our biobank search for novel therapeutic targets. Utilizing mRNA-microRNA correlations based on...
Rationale: Transbronchial lung cryobiopsy (TBLC) is an emerging technique for interstitial disease diagnosis. Good histopathologic agreement between TBLC and surgical biopsy (SLB) was demonstrated in the COLDICE (Cryobiopsy versus Open Lung Biopsy Diagnosis of Interstitial Disease Alliance) study; however, diagnostic confidence frequently lower than SLB. Objectives: To characterize specific features predictive usual pneumonia (UIP) corresponding SLB to identify clinical indices concordance....